{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T18:23:37Z","timestamp":1785781417682,"version":"3.56.0"},"reference-count":60,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T00:00:00Z","timestamp":1611100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Previous studies have indicated that childhood maltreatment (CM) may potentially influence the clinical symptomatology of obsessive-compulsive disorder (OCD). Here, we aimed to quantify the relationship between CM and obsessive-compulsive symptoms (OCS) and depressive symptoms in OCD through a meta-analysis.<\/jats:p><jats:p><jats:bold>Method:<\/jats:bold> We searched PubMed, Embase, Cochrane Library, and PsycARTICLES databases for articles reporting the association between CM and OCD on April 15, 2020. Random-effect models were used to quantify the relationship between CM and the severity of OCS and depressive symptoms in OCD.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Ten records with 1,611 OCD patients were included in the meta-analysis. The results revealed that CM is positively correlated with the severity of OCS [<jats:italic>r<\/jats:italic> = 0.10, 95%Confidence Interval (CI): 0.01\u20130.19, <jats:italic>P<\/jats:italic> = 0.04] as well as depressive symptoms in OCD (<jats:italic>r<\/jats:italic> = 0.15, 95%CI: 0.07\u20130.24, <jats:italic>P<\/jats:italic> = 0.0002). For the subtypes of CM, childhood emotional abuse (CEA) and childhood sexual abuse (CSA) was related with the severity of OCS (<jats:italic>r<\/jats:italic> = 0.11, 95%CI: 0.03\u20130.19, <jats:italic>P<\/jats:italic> = 0.009) and obsession (<jats:italic>r<\/jats:italic> = 0.13, 95%CI: 0.03\u20130.23, <jats:italic>P<\/jats:italic> = 0.01), respectively.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Our meta-analysis indicates that OCD patients who suffered more CM may exhibit more severe OCS and depressive symptoms.<\/jats:p>","DOI":"10.3389\/fpsyt.2020.612586","type":"journal-article","created":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T06:08:15Z","timestamp":1611122895000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":32,"title":["Association Between Childhood Maltreatment and Symptoms of Obsessive-Compulsive Disorder: A 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