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Psychiatry"],"abstract":"<jats:p>Pornography addiction and sexual dysfunction are increasingly prevalent in young men. Previous studies suggest that prenatal androgen exposure plays a role in addiction and sexual functionality. Here, we tested whether lower second-to-fourth finger length ratio (2D:4D) and later age at spermarche, both putative indicators of higher androgen levels <jats:italic>in utero<\/jats:italic>, correlate with online sexual compulsivity (OSC scale of ISST), erectile function (IIEF-5), and ejaculatory control (PEPA) in 4,370 young men (age IQR: 25\u201326 years) of the Cohort Study on Substance Use Risk Factors. Statistical analyses revealed that lower 2D:4D correlated with higher scores on the OSC scale. Moreover, higher age at spermarche correlated with higher OSC scores and decreased erectile function. Interestingly, OSC severity, but not the frequency of pornography use, correlated negatively with erectile function and ejaculatory control. This is the first study to associate two independent proxies of prenatal testosterone level with OSC. These findings provide novel insight into intrauterine predisposition of sexual behavior and related sexual function in adulthood.<\/jats:p>","DOI":"10.3389\/fpsyt.2021.517411","type":"journal-article","created":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T05:06:27Z","timestamp":1617685587000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Markers of Prenatal Androgen Exposure Correlate With Online Sexual Compulsivity and Erectile Function in Young Men"],"prefix":"10.3389","volume":"12","author":[{"given":"Verena N.","family":"Buchholz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christiane","family":"M\u00fchle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Cohort Study on Substance Use Risk Factors","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Kornhuber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Lenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,4,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1556\/2006.7.2018.109","article-title":"The dark side of internet: preliminary evidence for the associations of dark personality traits with specific online activities and problematic internet use","volume":"7","author":"Kircaburun","year":"2018","journal-title":"J Behav Addict"},{"key":"B2","doi-asserted-by":"publisher","first-page":"91","DOI":"10.3390\/jcm8010091","article-title":"Online porn addiction: what we know and what we don't-a systematic review","volume":"8","author":"de Alarcon","year":"2019","journal-title":"J Clin Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3390\/bs6030017","article-title":"Is internet pornography causing sexual dysfunctions? 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