{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:18:01Z","timestamp":1790209081224,"version":"4.1.0"},"reference-count":50,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T00:00:00Z","timestamp":1614211200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:p>\n                    Proposed treatments for severe and enduring anorexia nervosa (SE-AN) focus on quality of life, and psychological and social functioning. By de-emphasizing weight restoration as a priority, however, premature diagnosis of SE-AN may reduce potential for recovery. The present study assessed the effect of weight restoration, illness duration, and severity on treatment outcome 6 months after discharge from an intensive, meal-based behavioral treatment program. Participants included hospitalized adult women (\n                    <jats:italic>N<\/jats:italic>\n                    = 191) with AN or underweight other specified feeding and eating disorder (OSFED). Participants were characterized as short-term (ill &amp;lt;7 years;\n                    <jats:italic>n<\/jats:italic>\n                    = 74) or long-term ill (ill \u2265 7 years;\n                    <jats:italic>n<\/jats:italic>\n                    = 117). Compared with short-term ill, long-term ill patients were older, had lower lifetime body mass index (BMI), more prior admissions, and exhibited greater depression and neuroticism. Long-term vs. short-term ill patients gained weight at the same rate (~2 kg\/wk) and were equally likely to be weight restored by discharge (&amp;gt;75% reached BMI \u2265 19 kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    in both groups). At 6-month follow-up (\n                    <jats:italic>n<\/jats:italic>\n                    = 99), both groups had equivalent self-reported BMI, and depression, drive for thinness, body dissatisfaction, and bulimia scores. The only predictor of BMI \u2265 19 kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    at follow-up was discharge BMI. The likelihood of a BMI \u2265 19 kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    at follow-up was 5-fold higher for those with discharge BMI \u2265 19 kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    . Few studies of long-term ill inpatients with AN have examined the impact of full weight restoration on short-term outcomes. This study supports the therapeutically optimistic stance that, regardless of illness duration, hospitalized patients with AN benefit from gaining weight to a BMI \u2265 19 kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    .\n                  <\/jats:p>","DOI":"10.3389\/fpsyt.2021.641861","type":"journal-article","created":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T23:36:00Z","timestamp":1614209760000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":45,"title":["Discharge Body Mass Index, Not Illness Chronicity, Predicts 6-Month Weight Outcome in Patients Hospitalized With Anorexia Nervosa"],"prefix":"10.3389","volume":"12","author":[{"given":"Graham W.","family":"Redgrave","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen C.","family":"Schreyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janelle W.","family":"Coughlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura K.","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allisyn","family":"Pletch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela S.","family":"Guarda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,2,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.physbeh.2007.11.020","article-title":"Treatment of anorexia nervosa: insights and obstacles","volume":"94","author":"Guarda","year":"2008","journal-title":"Physiol Behav."},{"key":"B2","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s40519-016-0264-x","article-title":"A systematic review of the health-related quality of life and economic burdens of anorexia nervosa, bulimia nervosa, and binge eating disorder","volume":"21","author":"Agh","year":"2016","journal-title":"Eat Weight Disord."},{"key":"B3","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1002\/eat.20546","article-title":"A pilot case series using qualitative and quantitative methods: biological, psychological and social outcome in severe and enduring eating disorder (anorexia nervosa)","volume":"41","author":"Arkell","year":"2008","journal-title":"Int J Eat Disord."},{"key":"B4","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1097\/NMD.0000000000001124","article-title":"Managing patients with severe and enduring anorexia nervosa: when is enough, enough?","volume":"208","author":"Yager","year":"2020","journal-title":"J Nerv Ment Dis."},{"key":"B5","doi-asserted-by":"publisher","first-page":"184","DOI":"10.4088\/JCP.15m10393","article-title":"Recovery from anorexia nervosa and bulimia nervosa at 22-year follow-up","volume":"78","author":"Eddy","year":"2017","journal-title":"J Clin Psychiatry."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1002\/eat.22736","article-title":"Long-term outcome of anorexia nervosa: results from a large clinical longitudinal study","volume":"50","author":"Fichter","year":"2017","journal-title":"Int J Eat Disord."},{"key":"B7","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s40337-017-0145-3","article-title":"What happens after treatment? 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