{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T20:33:58Z","timestamp":1775075638681,"version":"3.50.1"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T00:00:00Z","timestamp":1640304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:p><jats:bold>Introduction:<\/jats:bold> The burden of personality disorders (PDs) in China is large and the focus on mental health services is increasing. However, there is a lack of sufficient evidence regarding the prevalence of comorbid PD in psychotic and non-psychotic disorders, and whether PDs have different distributions. We aimed to investigate the PD comorbidity distribution pattern between psychotic and non-psychotic disorders using a clinical population-based study.<\/jats:p><jats:p><jats:bold>Materials and Methods:<\/jats:bold> We conducted a cross-sectional study of 1,497 patients in Shanghai. PDs were screened using the Personality Diagnostic Questionnaire Fourth Edition Plus (PDQ-4+). All patients were interviewed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) Axis II (SCID-II). We compared the differences in PD comorbidities classified as the 10 types of PDs in the DSM-IV, in 531 patients with psychosis and 966 patients with non-psychotic disorders.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> More than one-third (37%) of patients with psychotic disorders met the criteria of at least one PD. Approximately half (46%) of patients with non-psychotic disorders met the criteria of at least one PD. Patients with non-psychotic disorders were more likely to meet the criteria of borderline (\u03c7<jats:sup>2<\/jats:sup> = 20.154, <jats:italic>p<\/jats:italic> &amp;lt; 0.001) and obsessive-compulsive PD (\u03c7<jats:sup>2<\/jats:sup> = 21.164, <jats:italic>p<\/jats:italic> &amp;lt; 0.001) diagnoses compared to those with psychotic disorders. In contrast, patients with psychotic disorders were more likely to meet the criteria of paranoid (\u03c7<jats:sup>2<\/jats:sup> = 11.144, <jats:italic>p<\/jats:italic> = 0.001) and schizotypal PD (\u03c7<jats:sup>2<\/jats:sup> = 14.004, <jats:italic>p<\/jats:italic> &amp;lt; 0.001) diagnoses than those with non-psychotic disorders.<\/jats:p><jats:p><jats:bold>Discussion:<\/jats:bold> PD comorbidity is common and comorbidity distribution pattern is varied in patients with psychotic and non-psychotic disorders, implicating the development of specific strategies that could screen and assess PDs in psychiatric clinical practice.<\/jats:p>","DOI":"10.3389\/fpsyt.2021.800047","type":"journal-article","created":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T05:56:47Z","timestamp":1640325407000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Prevalence of Comorbid Personality Disorder in Psychotic and Non-psychotic 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