{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:15:24Z","timestamp":1789539324886,"version":"build-2803163510"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>When the coronavirus disease 2019 (COVID-19) erupted in Yangzhou, China, at the end of July 2021, medical workers in Yangzhou immediately joined the frontline for the fight against the pandemic. This study aimed to identify the mental health and fatigue experienced by the medical workers in Yangzhou during the COVID-19 outbreak.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 233 medical workers who participated in the front-line work for more than 1 month through the questionnaire, including doctors, nurses, medical technicians and medical students. The generalized anxiety disorder-7 (GAD-7), patient health questionnaire-9 (PHQ-9), and Fatigue self-assessment scale (FSAS) were administered to the participants and their responses were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 233 eligible questionnaires were received. Among them, 130 people (57.08%) were probably anxious and 141 (60.52%) people were clinically depressed. Poor sleep was considered an independent risk factor for anxiety (OR = 7.164, 95% CI: 3.365 15.251, <jats:italic>p<\/jats:italic> = 0.000) and depression (OR = 6.899, 95% CI: 3.392 14.030, <jats:italic>p<\/jats:italic> = 0.000). A high PHQ-9 score was considered an independent risk factor for general fatigue (OR = 1.697, 95% CI: 1.481 1.944, <jats:italic>p<\/jats:italic> = 0.000). Mental fatigue (OR = 1.092, 95% CI: 1.027 1.161, <jats:italic>p<\/jats:italic> = 0.005) and fatigue response to sleep\/rest (OR = 1.043, 95% CI: 1.011 1.076 <jats:italic>p<\/jats:italic> = 0.008) were considered independent risk factors for general fatigue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Poor quality of sleep led to probable anxiety, depression, and general fatigue. Mental fatigue and fatigue response to sleep\/rest were independent risk factors for depression, which merits attention for battling COVID-19.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2022.1018069","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T07:12:51Z","timestamp":1665990771000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Mental health and fatigue status of the medical workforce during the COVID-19 outbreak in the Yangzhou city, China"],"prefix":"10.3389","volume":"13","author":[{"given":"Xiaojia","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunlong","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peipei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingzhu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoxiang","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e1099","DOI":"10.1016\/S2214-109X(22)00233-9","article-title":"Covid-19 in the 47 countries of the WHO African region: a modelling analysis of past trends and future patterns.","volume":"10","author":"Cabore","year":"2022","journal-title":"Lancet Glob Health."},{"key":"B2","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.cmi.2021.10.005","article-title":"Comparing covid-19 vaccines for their characteristics, effificacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative review.","volume":"28","author":"Fiolet","year":"2022","journal-title":"Clin Microbiol Infect."},{"key":"B3","doi-asserted-by":"publisher","first-page":"18754","DOI":"10.18632\/aging.103732","article-title":"Neurological manifestations in covid-19 and its possible mechanism.","volume":"12","author":"Tang","year":"2020","journal-title":"Aging."},{"key":"B4","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1038\/s41586-020-2012-7","article-title":"A pneumonia outbreak associated with a new coronavirus of probable bat origin.","volume":"579","author":"Zhou","year":"2020","journal-title":"Nature."},{"key":"B5","year":"2022","journal-title":"Covid-19 Situation Updates."},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000026520","article-title":"The correlation between mental health status, sleep quality, and inflflammatory markers, virus negative conversion time among patients confifirmed with 2019-nCoV during the covid-19 outbreak in China.","volume":"100","author":"Li","year":"2021","journal-title":"Medicine."},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17051729","article-title":"Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (covid-19) epidemic among the general population in China.","volume":"17","author":"Wang","year":"2020","journal-title":"Int J Env Res Pub He."},{"key":"B8","doi-asserted-by":"crossref","DOI":"10.1016\/S2215-0366(20)30047-X","article-title":"The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus.","volume":"7","author":"Kang","year":"2020","journal-title":"Lancet Psychiatry."},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.14607","article-title":"Evaluation of the mental health of health professionals in the covid-19 era. 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