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Both improved their depressive symptoms 4 weeks after the transplantation. Effects lasted up to 8 weeks in one patient. Gastrointestinal symptoms, constipation in particular, were reflected in microbiome changes and improved in one patient. This report suggests further FMT studies in depression could be worth pursuing and adds to awareness as well as safety assurance, both crucial in determining the potential of FMT in depression treatment.<\/jats:p>","DOI":"10.3389\/fpsyt.2022.815422","type":"journal-article","created":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T09:33:15Z","timestamp":1645090395000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":125,"title":["Fecal Microbiota Transplantation (FMT) as an Adjunctive Therapy for Depression\u2014Case Report"],"prefix":"10.3389","volume":"13","author":[{"given":"Jessica P. 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