{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:15:24Z","timestamp":1788552924748,"version":"build-2803163510"},"reference-count":39,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:00:00Z","timestamp":1662422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Nicotine and cannabis inhalation through vaping or electronic delivery systems has surged among young adults in the United States, particularly during the coronavirus disease pandemic. Tobacco and marijuana use are associated with select adverse mental health outcomes, including symptoms of major depressive disorder and suicidal behaviors. Given the need for addiction specialists to treat problematic substance use with an integrated approach, the association between non-suicidal self-injury (NSSI) and use of e-cigarettes, tobacco, marijuana, and alcohol was examined among a diverse sample of college students.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Healthy Minds Study data from 47,016 weighted observations, collected from college students in the 2018\u20132019 academic year, was used to explore associations between NSSI-related behaviors and past 30-day use of a vaping product (nicotine or marijuana). These relationships were assessed among those using vaping products only, and then among individuals using vaping products and alcohol, conventional cigarettes, and\/or marijuana. Hierarchical logistic regression models estimating the relationship between vaping and NSSI were computed to adjust for the effects of demographic factors, symptomatology of psychiatric disorders, and concurrent use of other substances.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A fifth (22.9%) of respondents disclosed past 12-month NSSI; they were significantly more likely to screen positive for depression or anxiety compared to young adults without NSSI. Rates of using vaping products, conventional cigarettes, marijuana, or other substances were higher among students with NSSI even after controlling for potential cofounders. Additionally, students who used a THC-based liquid in their e-cigarettes were more likely to endorse NSSI in comparison to those who used \u201cjust flavoring.\u201d However, young adults who vaped were less likely to disclose frequent NSSI-related behaviors than their peers who did not vape.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings revealed an association between past 12-month NSSI and past 30-day vaping in a sample of young adults. Further surveillance among college populations and examination of potential sociodemographic confounders is necessary to confirm these findings and advance the substance use and addiction field.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2022.911136","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T05:31:10Z","timestamp":1662442270000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["E-cigarettes and non-suicidal self-injury: Prevalence of risk behavior and variation by substance inhaled"],"prefix":"10.3389","volume":"13","author":[{"given":"Catherine W.","family":"Striley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara K.","family":"Nutley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolin C.","family":"Hoeflich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,9,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1097\/MCP.0000000000000757","article-title":"Vaping epidemic in US teens: problem and solutions","volume":"27","author":"Venkata","year":"2021","journal-title":"Curr Opin Pulm Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1097\/YCO.0000000000000617","article-title":"World vaping update","volume":"33","author":"Striley","year":"2020","journal-title":"Curr Opin Psychiatry."},{"key":"B3","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1080\/08897077.2019.1580241","article-title":"Understanding the implications of the \u201cvaping epidemic\u201d among adolescents and young adults: a call for action","volume":"40","author":"Chadi","year":"2019","journal-title":"Subst Abus."},{"key":"B4","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1080\/07448481.2018.1549557","article-title":"Where college students look for vaping information and what information they believe","volume":"68","author":"Dobbs","year":"2020","journal-title":"J Am Coll Health."},{"key":"B5","doi-asserted-by":"publisher","first-page":"e11953","DOI":"10.2196\/11953","article-title":"The messages presented in electronic cigarette-related social media promotions and discussion: scoping review","volume":"21","author":"McCausland","year":"2019","journal-title":"J Med Internet Res."},{"key":"B6","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1136\/tobaccocontrol-2020-056442","article-title":"Co-optation of harm reduction by Big Tobacco","volume":"30","author":"Dewhirst","year":"2020","journal-title":"Tob Control."},{"key":"B7","doi-asserted-by":"publisher","first-page":"L155","DOI":"10.1152\/ajplung.00110.2019","article-title":"Acute exposure to e-cigarettes causes inflammation and pulmonary endothelial oxidative stress in nonsmoking, healthy young subjects","volume":"317","author":"Chatterjee","year":"2019","journal-title":"Am J Physiol Lung Cell Mol Physiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1093\/cvr\/cvz256","article-title":"Cardiovascular risk of electronic cigarettes: a review of preclinical and clinical studies","volume":"116","author":"Buchanan","year":"2020","journal-title":"Cardiovasc Res."},{"key":"B9","doi-asserted-by":"publisher","first-page":"6349","DOI":"10.1073\/pnas.1920925117","article-title":"Potential for release of pulmonary toxic ketene from vaping pyrolysis of vitamin E acetate","volume":"117","author":"Wu","year":"2020","journal-title":"Proc Natl Acad Sci USA."},{"key":"B10","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.addbeh.2018.10.040","article-title":"E-cigarettes, alcohol use, and mental health: use and perceptions of e-cigarettes among college students, by alcohol use and mental health status","volume":"91","author":"Hefner","year":"2019","journal-title":"Addict Behav."},{"key":"B11","doi-asserted-by":"publisher","first-page":"107500","DOI":"10.1016\/j.drugalcdep.2019.06.005","article-title":"I wake up and hit the JUUL: analyzing Twitter for JUUL nicotine effects and dependence","volume":"204","author":"Sidani","year":"2019","journal-title":"Drug Alcohol Depend."},{"key":"B12","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1136\/tobaccocontrol-2019-055352","article-title":"Perceived addiction to vaping among youth and young adult regular vapers","volume":"30","author":"Camara-Medeiros","year":"2021","journal-title":"Tob Control."},{"key":"B13","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1056\/NEJMc1900830","article-title":"Youth vaping and associated risk behaviors - 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