{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:38:01Z","timestamp":1789180681040,"version":"build-2803163510"},"reference-count":32,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T00:00:00Z","timestamp":1664755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>To date, among individuals meeting ultra-high risk criteria for psychosis, the relationship between the presence of anxiety disorders and the risk of psychotic transition raises several unanswered questions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case description<\/jats:title><jats:p>This case report describes the clinical progression of a 17-year-old male initially presenting anxious symptoms meeting the DSM-V criteria for panic disorder. The patient also reported social withdraw, mild depressive symptoms, insomnia and fatigue. Over a 6 month period, a gradual onset of subthreshold psychotic symptoms suggested a prodromal phase of a psychotic disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Diagnostic assessment and therapeutic intervention<\/jats:title><jats:p>A detailed assessment of UHR criteria for psychosis was performed. The overall level of social and occupational functioning was assessed by the SOFAS, which showed a 35% drop over a 12 months period. The CAARMS, has also been administered. The patient met the diagnostic criteria for UHR, APS group. The care plan included psychiatric follow-up, pharmacologic treatment, individual psychological follow-up and individual and familial psychoeducation. Over a 6 months period, the patient did not experienced a first psychotic episode and presented a partial improvement of psychotic symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The DSM-V categorical approach does not seem to adapt well to early clinical presentations in transitional age youth. A transdiagnostic and dimensional approach allows to better identify at-risk patients of psychiatric disorders and implement early intervention strategies.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2022.990138","type":"journal-article","created":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T10:50:54Z","timestamp":1664794254000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case report: From anxiety disorders to psychosis, a continuum in transitional age youth?"],"prefix":"10.3389","volume":"13","author":[{"given":"Joana","family":"Reis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Marchini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Nicolis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Delvenne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,10,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1038\/s41380-021-01161-7","article-title":"Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies","volume":"27","author":"Solmi","year":"2022","journal-title":"Mol Psychiatry."},{"key":"B2","doi-asserted-by":"crossref","DOI":"10.1017\/9781139839518","volume-title":"Clinical Staging in Psychiatry","author":"McGorry","year":"2019"},{"key":"B3","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1002\/wps.20745","article-title":"Transdiagnostic clinical staging in youth mental health: a first international consensus statement","volume":"19","author":"Shah","year":"2020","journal-title":"World Psychiatry"},{"key":"B4","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1192\/S0007125000292714","article-title":"The epidemiology of early schizophrenia Influence of age and gender on onset and early course","volume":"23","author":"Hafner","year":"1994","journal-title":"Br J Psychiatry."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11920-013-0354-7","article-title":"Anxiety as a core aspect of schizophrenia","volume":"15","author":"Pallanti","year":"2013","journal-title":"Curr Psychiatry."},{"key":"B6","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1093\/schbul\/sbp148","article-title":"How prevalent are anxiety disorders in schizophrenia? 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