{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:23:35Z","timestamp":1790695415243,"version":"4.1.0"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:p>Diminished interest is a core feature of apathy that shows high prevalence in people with Mild and Major Neurocognitive disorders (NCD). In the clinical setting, apathy is mainly assessed using clinical scales and questionnaires, but new technologies are starting to be employed to complement classical instruments. Here, we explored the performance of the \u201cInterest game,\u201d a ludic application that assesses personal interests, in discriminating between persons with and without diminished interest based on the Apathy Diagnostic Criteria. Two hundred and twenty-seven elderly participants (56 healthy controls, 118 persons with mild-NCD, and 53 with major-NCD) completed the Interest game and were assessed by clinicians concerning the presence and the severity of apathy. Results showed that the application scores varied with the presence of apathy, the type of disorder, and the education level. Cutoff scores calculated for persons with Mild-NCD resulted in a sensitivity of 0.68 and a specificity of 0.65 for the main score index, suggesting the interest of employing this application in the clinical setting to complement the classical assessment.<\/jats:p>","DOI":"10.3389\/fpsyt.2023.1126479","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T01:48:10Z","timestamp":1679276890000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Cutoff scores for the \u201cInterest game\u201d, an application for the assessment of diminished interest in neurocognitive disorders"],"prefix":"10.3389","volume":"14","author":[{"given":"Valeria","family":"Manera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxane","family":"Fabre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyne","family":"Daumas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radia","family":"Zeghari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Derreumaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magali","family":"Payne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine","family":"Lemaire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Sacco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Auriane","family":"Gros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Robert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,3,20]]},"reference":[{"key":"ref1","volume-title":"Diagnostic and statistical manual of mental disorders: DSM-5","year":"2013"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"929","DOI":"10.3233\/JAD-160979","article-title":"The mild behavioral impairment checklist (MBI-C): a rating scale for neuropsychiatric symptoms in pre-dementia populations","volume":"56","author":"Ismail","year":"2017","journal-title":"JAD"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1038\/s41583-018-0029-9","article-title":"Neuroscience of apathy and anhedonia: a transdiagnostic approach","volume":"19","author":"Husain","year":"2018","journal-title":"Nat Rev Neurosci"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1093\/cercor\/bhj043","article-title":"Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits","volume":"16","author":"Levy","year":"1991","journal-title":"Cereb Cortex"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1176\/ajp.147.1.22","article-title":"Differential diagnosis and classification of apathy","volume":"147","author":"Marin","year":"1990","journal-title":"Am J Psychiatry"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.eurpsy.2008.09.001","article-title":"Proposed diagnostic criteria for apathy in Alzheimer\u2019s disease and other neuropsychiatric disorders","volume":"24","author":"Robert","year":"2009","journal-title":"Eur Psychiatry"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1017\/S1041610200006918","article-title":"Apathy and withdrawal","volume":"12","author":"Starkstein","year":"2000","journal-title":"Int Psychogeriatr"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1136\/jnnp.2007.136895","article-title":"The nosological position of apathy in clinical practice","volume":"79","author":"Starkstein","year":"2008","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.cortex.2020.04.001","article-title":"Definition: apathy","volume":"128","author":"Chong","year":"2020","journal-title":"Cortex"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1892","DOI":"10.1002\/alz.12358","article-title":"Diagnostic criteria for apathy in neurocognitive disorders","volume":"17","author":"Miller","year":"2021","journal-title":"Alzheimer\u2019s Dement"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.eurpsy.2018.07.008","article-title":"Is it time to revise the diagnostic criteria for apathy in brain disorders? 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