{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T09:31:52Z","timestamp":1766050312779,"version":"3.41.2"},"reference-count":45,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of Hunan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006190","name":"Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006190","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002822","name":"Central South University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002822","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study aimed to investigate the psychometric properties of the Affective Lability Scale-short form (ALS-SF) among Chinese patients with mood disorders, and to compare ALS-SF subscale scores between patients with major depressive disorder (MDD) and patients with bipolar disorder (BD) depression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 344 patients with mood disorders were included in our study. Participants were measured through a set of questionnaires including the Chinese version of ALS-SF, Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder 7-item (GAD-7), and NEO-Five Factor Inventory (NEO-FFI). Exploratory factor analysis and confirmatory factor analysis were applied to examine the psychometric properties of ALS-SF. Besides, correlation and regression analyses were performed to explore the relationship between affective lability and depression, anxiety, and neuroticism. Independent samples <jats:italic>t<\/jats:italic>-tests were used to compare the subscale scores of ALS-SF between the MDD and BD depression groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Results of factor analysis indicated that the model of ALS-SF was consistent with ALS-SF. The ALS-SF showed a solid validity and high internal consistency (Cronbach\u2019s alpha\u2009=\u20090.861). In addition, each subscale of ALS-SF was significantly correlated with PHQ-9, GAD-7, and NEO-FFI neuroticism subscale, except for the anger subscale showed no significant correlation with PHQ-9. Besides, the depression\/elation and anger factor scores in patients with BD depression were higher than in patients with MDD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study suggests that the Chinese version of ALS-SF has good reliability and validity for measuring affective lability in Chinese patients with mood disorders. Assessing affective lability would assist clinicians to distinguish between MDD and BP depression and may decrease the risks of misdiagnosis.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2023.1160791","type":"journal-article","created":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T08:04:38Z","timestamp":1680681878000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Psychometric property study of the Affective Lability Scale-short form in Chinese patients with mood disorders"],"prefix":"10.3389","volume":"14","author":[{"given":"Mohan","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuman","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenwen","family":"Ou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanyi","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaotian","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaqi","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumeng","family":"Ju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,4,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s00787-019-01355-z","article-title":"Affective lability in offspring of parents with major depressive disorder, bipolar disorder and schizophrenia","volume":"29","author":"Zwicker","year":"2020","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1017\/s0033291716003081","article-title":"Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders","volume":"47","author":"Aas","year":"2017","journal-title":"Psychol Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s40345-021-00238-0","article-title":"Characterization of affective lability across subgroups of psychosis spectrum disorders","volume":"9","author":"H\u00f8egh","year":"2021","journal-title":"Int J Bipolar Disord"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/s40345-021-00237-1","article-title":"Affective lability as a prospective predictor of subsequent bipolar disorder diagnosis: a systematic review","volume":"9","author":"Taylor","year":"2021","journal-title":"Int J Bipolar Disord"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1177\/0004867415579920","article-title":"Mood instability as a precursor to depressive illness: a prospective and mediational analysis","volume":"49","author":"Marwaha","year":"2015","journal-title":"Aust N Z J Psychiatry"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1002\/wcs.1177","article-title":"Cognitive aspects of depression","volume":"3","author":"Kircanski","year":"2012","journal-title":"Wiley Interdiscip Rev Cogn Sci"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1146\/annurev.clinpsy.1.102803.143916","article-title":"Cognitive vulnerability to emotional disorders","volume":"1","author":"Mathews","year":"2005","journal-title":"Annu Rev Clin Psychol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1521\/jscp.2006.25.7.726","article-title":"Cognitive vulnerability to unipolar and bipolar mood disorders","volume":"25","author":"Alloy","year":"2006","journal-title":"J Soc Clin Psychol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3389\/fpsyt.2019.00145","article-title":"Emotional biases and recurrence in major depressive disorder. 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