{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:27:19Z","timestamp":1787027239498,"version":"build-2736575974"},"reference-count":66,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T00:00:00Z","timestamp":1691107200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"\n Background<\/jats:title>\n Knowledge about patient characteristics predicting treatment dropout for post-traumatic stress disorder (PTSD) is scarce, whereas more understanding about this topic may give direction to address this important issue.<\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n \n Data were obtained from a randomized controlled trial in which a phase-based treatment condition (Eye Movement Desensitization and Reprocessing [EMDR] therapy preceded by Skills Training in Affect and Interpersonal Regulation [STAIR];\n n<\/jats:italic>\n \u2009=\u200957) was compared with a direct trauma-focused treatment (EMDR therapy only;\n n<\/jats:italic>\n \u2009=\u200964) in people with a PTSD due to childhood abuse. All pre-treatment variables included in the trial were examined as possible predictors for dropout using machine learning techniques.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n For the dropout prediction, a model was developed using Elastic Net Regularization. The ENR model correctly predicted dropout in 81.6% of all individuals. Males, with a low education level, suicidal thoughts, problems in emotion regulation, high levels of general psychopathology and not using benzodiazepine medication at screening proved to have higher scores on dropout.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Our results provide directions for the development of future programs in addition to PTSD treatment or for the adaptation of current treatments, aiming to reduce treatment dropout among patients with PTSD due to childhood abuse.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fpsyt.2023.1194669","type":"journal-article","created":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T07:34:52Z","timestamp":1691134492000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Predictors of treatment dropout in patients with posttraumatic stress disorder due to childhood abuse1"],"prefix":"10.3389","volume":"14","author":[{"given":"Susanne","family":"Bremer-Hoeve","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noortje I.","family":"van Vliet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne C.","family":"van Bronswijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafaele J.C.","family":"Huntjens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad","family":"de Jongh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten K.","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,8,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1111\/j.1600-0047.2004.00329.x","article-title":"Disability and quality of life impact of mental disorders in Europe: results from the European study of the epidemiology of mental disorders (ESEMeD) project","volume":"420","author":"Alonso","year":"2004","journal-title":"Acta Psychiatr Scand"},{"key":"ref2","first-page":"4","article-title":"Posttraumatic stress disorder: the burden to the individual and to society","volume":"61","author":"Kessler","year":"2000","journal-title":"J Clin Psychiatry"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1016\/j.comppsych.2012.02.009","article-title":"A meta-analysis of the association between posttraumatic stress disorder and suicidality: the role of comorbid depression","volume":"53","author":"Panagioti","year":"2012","journal-title":"Compr Psychiatry"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1097\/PSY.0b013e31803146d8","article-title":"Physical and mental comorbidity, disability, and suicidal behavior associated with posttraumatic stress disorder in a large community sample","volume":"69","author":"Sareen","year":"2007","journal-title":"Psychosom Med"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1017\/S0033291720000070","article-title":"Psychological treatments for post-traumatic stress disorder in adults: a network meta-analysis","volume":"50","author":"Mavranezouli","year":"2020","journal-title":"Psychol Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"100093","DOI":"10.1016\/j.jadr.2021.100093","article-title":"Dropout from guideline-recommended psychological treatments for posttraumatic stress disorder: a systematic review and meta-analysis","volume":"4","author":"Varker","year":"2021","journal-title":"J Affective Disorders Reports"},{"key":"ref7","first-page":"39","article-title":"Prognosis of PTSD in treated vs","volume":"12","author":"Usman","year":"2015","journal-title":"Non-Treated Groups J Pakistan Psychiatric Soc"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1818965","DOI":"10.1080\/20008198.2020.1818965","article-title":"Evidence of distinct profiles of ICD-11 post-traumatic stress disorder (PTSD) and complex PTSD in a south African sample","volume":"11","author":"Rink","year":"2020","journal-title":"Eur J Psychotraumatol"},{"key":"ref9","volume-title":"The ICD-11 for mortality and morbidity statistics. 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