{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T17:46:52Z","timestamp":1791654412272,"version":"4.3.4"},"reference-count":95,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T00:00:00Z","timestamp":1699488000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Postpartum depression (PPD) is a prevalent mental health condition affecting women globally within the first year following childbirth. Substance use during pregnancy has been associated with an increased risk of developing PPD, but the evidence remains inconclusive. This meta-analysis aims to comprehensively assess the effects of different substances on PPD risk, exploring potential modifiers and confounding factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To examine the proportion of PPD among substance users during pregnancy, compared to non-users, and investigate the specific risk associated with different substances (tobacco, alcohol, and non-specified substance use\/multiple substance use).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic literature search was conducted from inception to November 2022 using the Web of Science database (Clarivate Analytics), incorporating Web of Science Core Collection, the BIOSIS Citation Index, the KCI-Korean Journal Database, MEDLINE<jats:sup>\u00ae<\/jats:sup>, the Russian Science Citation Index, the SciELO Citation Index, and the Cochrane Central Register of Reviews, and Ovid\/PsycINFO databases. Inclusion criteria comprised original studies with pregnant women, using validated depression scales and substance use reporting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 26 included studies, encompassing 514,441 women, the pooled prevalence of PPD among substance users during pregnancy was 29% (95% CI 25\u201333). Meta-analyzes revealed an overall odds ratio (OR) of 3.67 (95% CI 2.31\u20135.85, <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.01) indicating a significantly higher risk of PPD among substance users compared to non-users. Subgroup analyzes demonstrated a higher risk for women with non-specified or multiple substance use (OR 4.67, 95% CI 2.59\u20138.41; <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.01) and tobacco use (OR 4.01, 95% CI 2.23\u20137.20; <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.01). Alcohol use showed a trend toward higher risk that did not reach statistical significance (OR 1.88, 95% CI 1.00\u20133.55; <jats:italic>p<\/jats:italic>\u2009=\u20090.051).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This meta-analysis provides evidence of an increased risk of PPD among pregnant substance users, particularly those using multiple substances or tobacco. However, caution is needed in interpreting the association with alcohol use due to its non-significant result.<\/jats:p><\/jats:sec><jats:sec><jats:title>Systematic review registration<\/jats:title><jats:p>This study protocol was registered at <jats:ext-link>PROSPERO<\/jats:ext-link> (registration number: CCRD42022375500).<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2023.1264998","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T04:32:20Z","timestamp":1699849940000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":31,"title":["Substance use during pregnancy and risk of postpartum depression: a systematic review and meta-analysis"],"prefix":"10.3389","volume":"14","author":[{"given":"Malein","family":"Pacho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Aymerich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borja","family":"Pedruzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Salazar de 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substance use disorders in pregnancy","year":"2014"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/j.jogn.2021.02.008","article-title":"Scoping review of the associations between perinatal substance use and perinatal depression and anxiety","volume":"50","author":"Pentecost","year":"2021","journal-title":"J Obstet Gynecol Neonatal Nurs"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e30898","DOI":"10.7759\/cureus.30898","article-title":"Risk factors of postpartum depression","volume":"14","author":"Agrawal","year":"2022","journal-title":"Cureus"},{"key":"ref10","volume-title":"Substance use in pregnancy","author":"Prince","year":"2023"},{"key":"ref11","year":"2022"},{"key":"ref12","year":"2014"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s40352-015-0015-5","article-title":"Pregnant women and substance use: fear, stigma, and barriers to 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Practical meta-analysis","author":"Lipsey","year":"2001"},{"key":"ref36","volume-title":"R: A language and environment for statistical computing","year":"2022"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1192\/bjp.150.6.782","article-title":"Detection of postnatal depression","volume":"150","author":"Cox","year":"1987","journal-title":"Br J Psychiatry"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1097\/01.MLR.0000093487.78664.3C","article-title":"The patient health Questionnaire-2","volume":"41","author":"Kroenke","year":"2003","journal-title":"Med Care"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.jad.2022.07.065","article-title":"Association between pre-pregnancy tobacco smoking and postpartum depression: a nationwide cohort study","volume":"316","author":"Yook","year":"2022","journal-title":"J Affect 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Scand"},{"key":"ref49","first-page":"193","article-title":"Risk factors for postpartum depression: a retrospective investigation at 4-weeks postnatal and a review of the literature","volume":"106","author":"McCoy","year":"2006","journal-title":"J Am Osteopath Assoc"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1186\/s12884-018-2072-y","article-title":"Magnitude of postpartum depression and associated factors among women in Mizan Aman town, bench Maji zone, Southwest Ethiopia","volume":"18","author":"Toru","year":"2018","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3389\/fpubh.2022.882205","article-title":"Magnitude and determinant factors of postpartum depression among mothers attending their postnatal and vaccination Services at Public Health Institutions of Addis Ababa, Ethiopia","volume":"10","author":"Wake","year":"2022","journal-title":"Front Public 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Psychiatry"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/s12884-022-04392-w","article-title":"Effects of family relationship and social support on the mental health of Chinese postpartum women","volume":"22","author":"Qi","year":"2022","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"109","DOI":"10.2174\/1745017901814010109","article-title":"Domestic violence as a risk factor for postpartum depression among Ethiopian women: facility based study","volume":"14","author":"Adamu","year":"2018","journal-title":"Clin Pract Epidemiol Ment Health"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.eurpsy.2018.10.005","article-title":"Maternal violence experiences and risk of postpartum depression: a meta-analysis of cohort studies","volume":"55","author":"Zhang","year":"2019","journal-title":"Eur 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