{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T20:28:15Z","timestamp":1784147295408,"version":"3.55.0"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T00:00:00Z","timestamp":1725235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Autistic traits (AT) seem to be particularly frequent among patients with borderline personality disorder (BPD). Moreover, the autism spectrum is considered a vulnerability factor for the development of post-traumatic stress disorder (PTSD) symptoms, increasing the vulnerability of BPD subjects toward the development of a stress-related disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The study aimed to investigate the association between AT and trauma-related symptoms in a clinical sample of patients with BPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 48 patients with a clinical diagnosis of BPD and 52 healthy control (HC) subjects were recruited and assessed with the Adult Autism Subthreshold Spectrum Self-Report (AdAS Spectrum) questionnaire and the Trauma and Loss Spectrum\u2014Self-Report questionnaire (TALS-SR). The BPD group was divided into two subgroups: BPD with a symptomatological diagnosis of PTSD (pBPD = 25) and BPD not diagnosed with PTSD (No-pBPD = 23).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The clinical sample scored significantly higher in almost all AdAS domains. Moreover, pBPD groups reported higher AdAS and TALS-SR scores in the total and in various domains than the No-pBPD group, which scored higher in several domains than HC. AdAS <jats:italic>Restricted interests and rumination<\/jats:italic> domain scores were positive predictors of BPD presence independently from PTSD, while <jats:italic>Inflexibility and adherence to routine<\/jats:italic> domain was a negative predictor. Finally, AdAS <jats:italic>Hyper\/hyporeactivity to sensory stimuli<\/jats:italic> domain was a positive predictor only for inclusion in the pBPD group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study confirmed the existence of a statistically significant relationship between the autism spectrum and BPD, while BPD subjects diagnosed with PTSD seem to show a higher autism spectrum burden.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2024.1443365","type":"journal-article","created":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T04:39:58Z","timestamp":1725251998000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Autistic traits as predictors of post-traumatic stress symptoms among patients with borderline personality disorder"],"prefix":"10.3389","volume":"15","author":[{"given":"Barbara","family":"Carpita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Bonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Schifanella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetta","family":"Nardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Amatori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Massimetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan Mirko","family":"Cremone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Pini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Dell\u2019Osso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,9,2]]},"reference":[{"key":"B1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR Fifth edition, text revision)","year":"2022"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2006.09.019","article-title":"DSM-IV personality disorders in the National Comorbidity Survey Replication","volume":"62","author":"Lenzenweger","year":"2007","journal-title":"Biol Psychiatry"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.0589","article-title":"Borderline personality disorder: A review","volume":"329","author":"Leichsenring","year":"2023","journal-title":"JAMA"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1111\/inm.12737","article-title":"Borderline Personality Disorder: To diagnose or not to diagnose? 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