{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:45:11Z","timestamp":1789706711320,"version":"4.0.1"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study investigated the effectiveness of a digital therapeutic intervention for individuals with alcohol use problems. Digital interventions are increasingly considered viable alternatives or complements to traditional face-to-face treatments, especially in improving accessibility and adherence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 30 outpatients were recruited and randomly assigned to either a digital intervention group or a face-to-face cognitive behavioral therapy (CBT) control group. After excluding two dropouts, data from 28 participants were analyzed. The digital intervention group received a 12-week mobile application-based CBT program, which included 84 video-based CBT sessions. The control group received an 8-session standardized face-to-face CBT program over the same period. Both groups were also provided with a mobile application that included a diary feature for tracking alcohol consumption, cravings, and mood. Assessments were conducted at baseline, mid-treatment (week 4), and post-treatment (week 12) to evaluate risky drinking, craving, readiness for change, depression, anxiety, and alcohol-related symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The primary outcome, abstinence rate during weeks 9\u201312, was significantly higher in the digital intervention group (73.3%) compared to the control group (30.8%). Regarding secondary outcomes, the digital group showed significantly greater reductions in risky drinking, craving, and anxiety levels compared to the control group. However, no significant group differences were found for other outcome variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>These findings suggest that digital CBT-based interventions can be an effective alternative to face-to-face CBT for reducing alcohol use and related symptoms. The study highlights the potential of digital therapeutics in addiction treatment, while acknowledging limitations such as small sample size and short follow-up period. Future research should explore long-term effects and broader clinical applicability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical trial registration<\/jats:title><jats:p><jats:uri>https:\/\/cris.nih.go.kr\/cris\/search\/detailSearch.do?seq=29717&amp;amp;status=5&amp;amp;seq_group=29562&amp;amp;search_page=M<\/jats:uri>, identifier KCT0010289.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2025.1486338","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T05:25:27Z","timestamp":1749446727000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["The effects of cognitive behavioral therapy-based digital therapeutic intervention on patients with alcohol use disorder"],"prefix":"10.3389","volume":"16","author":[{"given":"Song-Hee","family":"Lim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Kyoung","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moo Eob","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-hyun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Kyu","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,6,9]]},"reference":[{"key":"B1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"2013"},{"key":"B2","volume-title":"Global Status Report on Alcohol and Health 2018","year":"2018"},{"key":"B3","doi-asserted-by":"publisher","first-page":"652","DOI":"10.3350\/cmh.2020.0160","article-title":"Global and regional impacts of alcohol use on public health: Emphasis on alcohol policies","volume":"26","author":"Park","year":"2020","journal-title":"Clin Mol Hepatology"},{"key":"B4","volume-title":"Title of the Report or Document","year":"2019"},{"key":"B5","doi-asserted-by":"publisher","first-page":"13","DOI":"10.12934\/jkpmhn.2011.20.1.13","article-title":"Effects of women-focused relapse prevention program on abstinence self-efficacy and depression in alcoholic women","volume":"20","author":"Bong","year":"2011","journal-title":"J Korean Acad Psychiatr Ment Health Nurs"},{"key":"B6","volume-title":"Tackling Harmful Alcohol Use: Economics and Public Health Policy","year":"2015"},{"key":"B7","unstructured":"Moon\n              IS\n            \n          \n          Seoul, Korea\n          Konyang University\n          The Effects of Stress Coping Style and Depression on Drinking Behavior of Undergraduate Students (Master\u2019s thesis)\n          \n          2008"},{"key":"B8","first-page":"61","article-title":"A study on the relationship between the factors and frequency of alcoholism relapse focusing on the moderating effect of gender","volume":"42","author":"Shon","year":"2014","journal-title":"Ment Health Soc Work"},{"key":"B9","article-title":"Clinical variables affecting relapse of alcoholism","volume":"33","author":"Kim","year":"1994","journal-title":"J Korean Neuropsychiatr Assoc"},{"key":"B10","article-title":"Cognitive and behavior therapies","volume-title":"Substance Abuse: A Comprehensive Textbook","author":"Bruce","year":"1997"},{"key":"B11","volume-title":"Textbook of Substance Abuse Treatment","author":"Galanter","year":"1999"},{"key":"B12","article-title":"Relapse prevention","volume-title":"Textbook of Substance Abuse Treatment","author":"Marlatt","year":"1999"},{"key":"B13","first-page":"7","volume-title":"Group Treatment for Substance Abuse: A Stages-of-Change Therapy Manual","author":"Velasquez","year":"2001"},{"key":"B14","volume-title":"Motivational Interviewing","author":"William","year":"1991"},{"key":"B15","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3109\/10826084.2011.521069","article-title":"Cognitive function and treatment response in a randomized clinical trial of computer-based training in cognitive-behavioral therapy","volume":"46","author":"Carroll","year":"2011","journal-title":"Subst Use Misuse"},{"key":"B16","doi-asserted-by":"crossref","DOI":"10.4306\/jknpa.2019.58.3.173","article-title":"Motivational enhancement therapy and cognitive behavioral therapy for alcohol use disorders","volume":"58","author":"Lee","year":"2019","journal-title":"J Korean Neuropsychiatr Assoc"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2010.03214.x","article-title":"Can stand-alone computer-based interventions reduce alcohol consumption","volume":"106","author":"Khadjesari","year":"2011","journal-title":"A systematic review. 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