{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T23:50:28Z","timestamp":1789516228279,"version":"build-2803163510"},"reference-count":43,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T00:00:00Z","timestamp":1739145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Many adolescents with non suicidal self injury disorder have suicidal ideation. However, the specific characteristics of adolescents with NSSI-D that contribute to high suicide risk remain unclear. This study observes the association between depressive and anxiety symptoms and suicide risk among adolescents with non suicidal self injury disorder, and explores the mechanism underlying the high risk of suicide in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Adolescents with non suicidal self injury disorder and their parents from a psychiatric outpatient clinic were selected to conduct paper questionnaires to measure their sociodemographic conditions. The Mini International Neuropsychiatric Interviews\u2019 Suicidality Module(MINISM) was used to assess suicide risk of participants. The Self-Rating Depression Scale(SDS), Self-Rating Anxiety Scale(SAS), and Piers-Harris Children\u2019s Self-Concept Scale(PHCSS) were used to measure depressive and anxiety symptoms, and self-concept of adolescents with non suicidal self injury disorder. According to the high suicide risk cutoff value of MINISM, the sample was divided into high suicide risk group and non-high suicide risk group. We performed descriptive and correlation statistical and network analysis to study the types of depressive and anxiety symptoms associated with suicide risk and the mechanism underlying suicide risk among non suicidal self injury disorder adolescents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 112 non suicidal self injury disorder adolescent participants were included in this study. Severe depressive symptoms(OR=8.205, 95%CI=3.454-19.490) and severe anxiety symptoms(OR=3.926, 95%CI=1.613-9.554) are associated with a high risk of suicide. The father\u2019s college\/university education(p&amp;lt;0.01) is associated with severe anxiety symptoms, and low self-concept(p&amp;lt;0.01) is associated with severe depressive symptoms. Network analysis suggests the centrality of anxiety symptoms and father\u2019s education level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of statistical analysis suggest that severe depressive symptoms are related to the high risk of suicide (based on MINISM) in adolescents with NSSI-D statistical significantly, and anxiety symptoms and low self-concept are associated with depressive symptoms in NSSI-D adolescents. Interventions targeting anxiety symptoms in adolescents with NSSI-D may help reduce their suicide risk.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2025.1546039","type":"journal-article","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T06:50:43Z","timestamp":1739170243000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Association analysis of suicide risk assessed with Mini International Neuropsychiatric Interviews\u2019 Suicidality Module in adolescents with non suicidal self injury disorder"],"prefix":"10.3389","volume":"16","author":[{"given":"Shuo","family":"Geng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lele","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueping","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingdong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyu","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,2,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1007\/s11920-017-0767-9","article-title":"Non-suicidal self-injury in adolescence","volume":"19","author":"Brown","year":"2017","journal-title":"Curr Psychiatry Rep"},{"key":"B2","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: Dsm-5","author":"Association","year":"2013"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2012.05.003","article-title":"Examining the link between nonsuicidal self-injury and suicidal behavior: a review of the literature and an integrated model","volume":"32","author":"Hamza","year":"2012","journal-title":"Clin Psychol Rev"},{"key":"B4","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/s13034-015-0062-7","article-title":"The DSM-5 diagnosis of nonsuicidal self-injury disorder: a review of the empirical literature","volume":"9","author":"Zetterqvist","year":"2015","journal-title":"Child Adolesc Psychiatry Ment Health"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2018.06.033","article-title":"The associations between non-suicidal self-injury and first onset suicidal thoughts and behaviors","volume":"239","author":"Kiekens","year":"2018","journal-title":"J Affect Disord"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1177\/13591045231169087","article-title":"Risk factors and protective factors for nonsuicidal self-injury in adolescents: A hospital- and school-based case-control study","volume":"28","author":"Geng","year":"2023","journal-title":"Clin Child Psychol Psychiatry"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2022.03.021","article-title":"Age and gender effects on non-suicidal self-injury, and their interplay with psychological distress","volume":"306","author":"Wilkinson","year":"2022","journal-title":"J Affect Disord"},{"key":"B8","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1186\/s12888-022-03763-z","article-title":"Non suicidal self injury and suicidal behavior among adolescents: co-occurrence and associated risk factors","volume":"22","author":"Poudel","year":"2022","journal-title":"BMC Psychiatry"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(19)30030-6","article-title":"Predictors of future suicide attempt among adolescents with suicidal thoughts or non-suicidal self-harm: a population-based birth cohort study","volume":"6","author":"Mars","year":"2019","journal-title":"Lancet Psychiatry"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1177\/0020764015579739","article-title":"Nonsuicidal self-injury in Indian adolescents: Nonexistent or unacknowledged","volume":"61","author":"Aggarwal","year":"2015","journal-title":"Int J Soc Psychiatry"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1002\/pchj.v11.2","article-title":"Association between depressive symptoms and suicidal risk: Based on self-reported and clinical-interview measurements from a network perspective","volume":"11","author":"Shen","year":"2022","journal-title":"Psych J"},{"key":"B12","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1186\/s12888-021-03392-y","article-title":"Prevalence and risk factors for non-suicidal self-injury among patients with depression or bipolar disorder in China","volume":"21","author":"Wang","year":"2021","journal-title":"BMC Psychiatry"},{"key":"B13","doi-asserted-by":"publisher","first-page":"e12450","DOI":"10.1111\/appy.12450","article-title":"Suicide prevention in psychiatric patients","volume":"13","author":"Wasserman","year":"2021","journal-title":"Asia Pac Psychiatry"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2022.1256","article-title":"Prevalence and correlates of suicide and nonsuicidal self-injury in children: A systematic review and meta-analysis","volume":"79","author":"Liu","year":"2022","journal-title":"JAMA Psychiatry"},{"key":"B15","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s13034-015-0051-x","article-title":"Parenting behavior in families of female adolescents with nonsuicidal self-injury in comparison to a clinical and a nonclinical control group","volume":"9","author":"Tschan","year":"2015","journal-title":"Child Adolesc Psychiatry Ment Health"},{"key":"B16","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1111\/j.1467-8721.2009.01613.x","article-title":"Why do people hurt themselves? New insights into the nature and functions of self-injury","volume":"18","author":"Nock","year":"2009","journal-title":"Curr Dir Psychol Sci"},{"key":"B17","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1177\/1529100620920576","article-title":"Education and cognitive functioning across the life span","volume":"21","author":"L\u00f6vd\u00e9n","year":"2020","journal-title":"Psychol Sci Public Interest"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2012.10.012","article-title":"Adverse childhood experiences and their impact on frequency, severity, and the individual function of nonsuicidal self-injury in youth","volume":"206","author":"Kaess","year":"2013","journal-title":"Psychiatry Res"},{"key":"B19","doi-asserted-by":"publisher","first-page":"e0213700","DOI":"10.1371\/journal.pone.0213700","article-title":"Socioeconomic status, stressful life situations and mental health problems in children and adolescents: Results of the German BELLA cohort-study","volume":"14","author":"Reiss","year":"2019","journal-title":"PloS One"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.adolescence.2009.10.012","article-title":"Brief report: the association between non-suicidal self-injury, self-concept and acquaintance with self-injurious peers in a sample of adolescents","volume":"33","author":"Claes","year":"2010","journal-title":"J Adolesc"},{"key":"B21","doi-asserted-by":"publisher","first-page":"17:329","DOI":"10.1186\/s12888-017-1489-6","article-title":"Screening for anxiety and depression: reassessing the utility of the Zung scales","author":"Dunstan","year":"2017","journal-title":"BMC Psychiatry"},{"key":"B22","doi-asserted-by":"publisher","first-page":"e0135386","DOI":"10.1371\/journal.pone.0135386","article-title":"The multimedia piers-harris children\u2019s self-concept scale 2: its psychometric properties, equivalence with the paper-and-pencil version, and respondent preferences","volume":"10","author":"Flahive M hsin","year":"2015","journal-title":"PloS One"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1109\/TPAMI.2022.3225073","article-title":"One-hot graph encoder embedding","volume":"45","author":"Shen","year":"2023","journal-title":"IEEE Trans Pattern Anal Mach Intell"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1111\/biom.12653","article-title":"Pearson\u2019s chi-square test and rank correlation inferences for clustered data","volume":"73","author":"Shih","year":"2017","journal-title":"Biometrics"},{"key":"B25","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.cpr.2015.02.009","article-title":"Gender differences in the prevalence of nonsuicidal self-injury: A meta-analysis","volume":"38","author":"Bresin","year":"2015","journal-title":"Clin Psychol Rev"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1196\/nyas.2008.1124.issue-1","article-title":"The adolescent brain","volume":"1124","author":"Casey","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"B27","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3758\/s13428-017-0862-1","article-title":"Estimating psychological networks and their accuracy: A tutorial paper","volume":"50","author":"Epskamp","year":"2018","journal-title":"Behav Res"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1037\/met0000555","article-title":"A general Monte Carlo method for sample size analysis in the context of network models","author":"Constantin","year":"2023","journal-title":"psychol Methods"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1080\/00029890.1992.11995869","article-title":"Two notes on notation","volume":"99","author":"Knuth","year":"1992","journal-title":"Am Math Monthly"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.2c00526","article-title":"Sequential properties representation scheme for recurrent neural network-based prediction of therapeutic peptides","volume":"62","author":"Otovi\u0107","year":"2022","journal-title":"J Chem Inf Model"},{"key":"B31","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/1471-2288-9-56","article-title":"Bias in odds ratios by logistic regression modelling and sample size","volume":"9","author":"Nemes","year":"2009","journal-title":"BMC Med Res Methodol"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2015.05.066","article-title":"Examining the unique relations between anxiety sensitivity factors and suicidal ideation and past suicide attempts","volume":"228","author":"Allan","year":"2015","journal-title":"Psychiatry Res"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1037\/ccp0000342","article-title":"Anxiety sensitivity and suicidal ideation\/suicide risk: A meta-analysis","volume":"86","author":"Stanley","year":"2018","journal-title":"J Consult Clin Psychol"},{"key":"B34","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s11920-018-0893-z","article-title":"Psychological pain, depression, and suicide: recent evidences and future directions","volume":"20","author":"Conejero","year":"2018","journal-title":"Curr Psychiatry Rep"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.2018.27","article-title":"Depression and hopelessness as risk factors for suicide ideation, attempts and death: meta-analysis of longitudinal studies","volume":"212","author":"Ribeiro","year":"2018","journal-title":"Br J Psychiatry"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.17324","article-title":"Prevalence of depression, depressive symptoms, and suicidal ideation among medical students: A systematic review and meta-analysis","volume":"316","author":"Rotenstein","year":"2016","journal-title":"JAMA"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1007\/s10508-022-02316-5","article-title":"Internalized homophobia and suicide ideation among sexual minority adults: the serial mediation of core self-evaluations and depression","volume":"51","author":"Munn","year":"2022","journal-title":"Arch Sex Behav"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1002\/pchj.v11.6","article-title":"Relationship of explicit\/implicit self-esteem discrepancies, suicide ideation, and suicide risk in patients with major depressive disorder","volume":"11","author":"Yin","year":"2022","journal-title":"Psych J"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1002\/cpp.2593","article-title":"The relationship between self-criticism and suicide probability","volume":"28","author":"O\u2019Neill","year":"2021","journal-title":"Clin Psychol Psychother"},{"key":"B40","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1186\/s40359-024-01729-2","article-title":"Network analysis of the relationship between non-suicidal self-injury, depression, and childhood trauma in adolescents","volume":"12","author":"Lei","year":"2024","journal-title":"BMC Psychol"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-012-0130-x","article-title":"The influence of parental education on child mental health in Spain","volume":"22","author":"Sonego","year":"2013","journal-title":"Qual Life Res"},{"key":"B42","doi-asserted-by":"publisher","first-page":"e19","DOI":"10.1017\/S204579602200004X","article-title":"Parental education and youth suicidal behaviours: a systematic review and meta-analysis","volume":"31","author":"Chen","year":"2022","journal-title":"Epidemiol Psychiatr Sci"},{"key":"B43","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1111\/j.1651-2227.1988.tb10860.x","article-title":"Father\u2019s influence in the development of infant\u2019s relationships","volume":"344","author":"Pruett","year":"1988","journal-title":"Acta Paediatr Scand Suppl"}],"container-title":["Frontiers in Psychiatry"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyt.2025.1546039\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T06:50:46Z","timestamp":1739170246000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyt.2025.1546039\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,10]]},"references-count":43,"alternative-id":["10.3389\/fpsyt.2025.1546039"],"URL":"https:\/\/doi.org\/10.3389\/fpsyt.2025.1546039","relation":{},"ISSN":["1664-0640"],"issn-type":[{"value":"1664-0640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,10]]},"article-number":"1546039"}}