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This property has also prompted the use of ECT in managing status epilepticus (SE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>We report two distinct cases of prolonged seizures during ECT that persisted for more than 5 min despite administration of propofol and lorazepam, ultimately meeting criteria for status epilepticus (SE). The first case involved an 80-year old woman with severe psychotic depression starting ECT, while the second case involved a 30-year old man receiving maintenance ECT for difficult-to-treat schizophrenic psychosis. In both cases, SE was promptly terminated by restimulation, defined as an additional stimulus delivered within the same ECT session. After epilepsy and intracranial pathology were ruled out, ECT was safely resumed in both patients after switching from etomidate to propofol induction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Status epilepticus after ECT can be resolved by restimulation when standard interventions are unsuccessful, thereby avoiding potential neurological complications. We provide an overview of the mechanism and current clinical evidence supporting this strategy, and propose an amended clinical practice protocol for SE after ECT.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2025.1576374","type":"journal-article","created":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T12:23:37Z","timestamp":1748521417000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Restimulation could stop status epilepticus after electroconvulsive therapy: 2 case reports"],"prefix":"10.3389","volume":"16","author":[{"given":"Michael","family":"Pinchuk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaat","family":"Hebbrecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Sienaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabet","family":"Boon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filip","family":"Bouckaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,5,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1192\/bjp.2017.28","article-title":"Prediction of electroconvulsive therapy response and remission in major depression: Meta-analysis","volume":"212","author":"Van Diermen","year":"2018","journal-title":"Br J Psychiatry"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1017\/neu.2018.32","article-title":"ECT in schizophrenia: A review of the evidence","volume":"31","author":"Grover","year":"2019","journal-title":"Acta Neuropsychiatr"},{"key":"B3","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/S0140-6736(03)12705-5","article-title":"Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis","volume":"361","year":"2003","journal-title":"Lancet"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2009.01.023","article-title":"The origins of electroconvulsive therapy: Prof. Bini\u2019s first report on ECT","volume":"120","author":"Faedda","year":"2010","journal-title":"J Affect Disord"},{"key":"B5","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/j.1600-0447.1960.tb08347.x","article-title":"Experimental studies of the mode of action of electroconvulsive therapy: Introduction","volume":"35","author":"Ottosson","year":"1960","journal-title":"Acta Psychiatr Scand Suppl"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2007.00971.x","article-title":"Electroconvulsive therapy in melancholia: The role of hippocampal neurogenesis","volume":"115","author":"Bolwig","year":"2007","journal-title":"Acta Psychiatr Scand"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1177\/070674371105600104","article-title":"How does electroconvulsive therapy work? 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