{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:06:13Z","timestamp":1791558373978,"version":"4.3.4"},"reference-count":59,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:p>\n                    The postpartum period is notorious for rapid and profound changes for birthing individuals and their families. Significant shifts to hormonal and physical health, routines and family roles, and the salience of personal and community risk factors all contribute to potential psychiatric and psychological distress for parents, sometimes diagnosed as a postpartum mood or anxiety disorder (PMAD). Existing pharmacologic treatment modalities for PMADs do not comprehensively address the profound shifts of the postpartum period, often inadequate at reaching peak therapeutic efficacy in a shorter time frame, in patient accessibility, or offering sustained benefit. Ketamine assisted psychotherapy (KAP), is increasingly recognized as a therapeutic option for a range of psychiatric disorders and has been explored as a modality to\n                    <jats:italic>prevent<\/jats:italic>\n                    PMADs when used during Cesarean births. This retrospective case series examines three cases where ketamine assisted psychotherapy (KAP) was introduced during the first two years postpartum as part of a comprehensive treatment plan for PMADs. This study describes the utility of ketamine assisted psychotherapy to the postpartum individual, and offers perspective on the impact of psychedelic insights through treatment of PMAD symptoms\n                  <\/jats:p>","DOI":"10.3389\/fpsyt.2025.1661604","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T16:14:34Z","timestamp":1769098474000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Ketamine assisted psychotherapy in postpartum mood and anxiety disorders: a limited case series"],"prefix":"10.3389","volume":"16","author":[{"given":"Alka","family":"Christnacht","sequence":"first","affiliation":[{"name":"College of Nursing, Seattle University","place":["Seattle, WA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therry Rose","family":"Eparwa","sequence":"additional","affiliation":[{"name":"College of Nursing, Seattle University","place":["Seattle, WA, United States"]},{"name":"Advanced Integrative Medical Science Institute (AIMS) Institute","place":["Seattle, WA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Whinkin","sequence":"additional","affiliation":[{"name":"Advanced Integrative Medical Science Institute (AIMS) Institute","place":["Seattle, WA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Advanced Integrative Medical Science Institute (AIMS) Institute","place":["Seattle, WA, United States"]},{"name":"University of Washington, Department of Geography","place":["Seattle, WA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"B1","volume-title":"Diagnostic and statistical manual of mental disorders","year":"2022"},{"key":"B2","unstructured":"Postpartum depression\n          \n          2024"},{"key":"B3","unstructured":"Overview: Postnatal depression\n          \n          2022"},{"key":"B4","unstructured":"Rich\n              M\n            \n          \n          UNICEF\n          What is postpartum depression?"},{"key":"B5","unstructured":"Launch of the WHO guide for integration of perinatal mental health in maternal and child health services\n          \n          2022"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-022-01334-3","article-title":"Suicide and maternal mortality","volume":"24","author":"Chin","year":"2022","journal-title":"Curr Psychiatry Rep"},{"key":"B7","volume-title":"Pregnancy-related deaths: data from maternal mortality review committees in 36 US states, 2017\u20132019","author":"Trost","year":"2022"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1177\/1745506519844044","article-title":"Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes","volume":"15","author":"Slomian","year":"2019","journal-title":"Women\u2019s Health"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jad.2018.12.132","article-title":"Trajectories of maternal distress and risk of child developmental delays: Findings from the All Our Families (AOF) pregnancy cohort","volume":"248","author":"Mughal","year":"2019","journal-title":"J Affect Disord"},{"key":"B10","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1046\/j.1365-2648.2003.02857.x","article-title":"Paternal postpartum depression, its relationship to maternal postpartum depression, and implications for family health","volume":"45","author":"Goodman","year":"2004","journal-title":"J Adv Nurs"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3109\/01612840.2012.673054","article-title":"Postpartum depression is a family affair: Addressing the impact on mothers, fathers, and children","volume":"33","author":"Letourneau","year":"2012","journal-title":"Issues Ment Health Nurs"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.30898","article-title":"Risk factors of postpartum depression","volume":"14","author":"Agrawal","year":"2022","journal-title":"Cureus"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2021.09.099","article-title":"The development and application of a prediction model for postpartum depression: Optimizing risk assessment and prevention in the clinic","volume":"296","author":"Yang","year":"2022","journal-title":"J Affect Disord"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1176\/appi.focus.20190045","article-title":"Is postpartum depression different from depression occurring outside of the perinatal period? 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