{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:59:14Z","timestamp":1788281954630,"version":"build-2803163510"},"reference-count":102,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Mood disorders are highly prevalent and associated with substantial impairment. This study examines medication adherence (MA), treatment satisfaction (TS), and patient\u2013doctor relationships (PDRs) among adult patients with mood disorders at a Saudi tertiary hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study\u2019s tool employed a questionnaire developed by the researchers, along with the Arabic versions of the Medication Adherence Rating Scale, the Treatment Satisfaction Questionnaire for Medication (TSQM), and the Patient\u2013Doctor Relationship Questionnaire (PDRQ).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the 260 participants, 79.2% demonstrated good MA, 34.23% exhibited low TS, and 62.31% reported good PDRs. Good MA was significantly associated with higher global TSQM scores (adjusted odds ratio [AOR] = 1.04; 95% confidence interval [CI]: 1.02\u20131.06;\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001) and better PDR (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.034). Illness duration was a significant factor associated with MA (AOR = 0.14; 95% CI: 0.02\u20130.86;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.034 for 1\u20135 years compared with &amp;lt; 1 year), TS (AOR = 6.07; 95% CI, 1.80\u201320.48;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.004 for &amp;gt; 10 years compared with &amp;lt; 1 year), and PDR (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.028). Being supported by family and friends \u201cto some extent\u201d was associated with lower TS (AOR = 0.52; 95% CI: 0.30\u20130.92;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.024) and poorer PDR (AOR = 0.37; 95% CI: 0.19\u20130.70;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.002) compared with those receiving more support. Education level was significantly associated with TS, specifically for participants with a bachelor\u2019s degree compared with uneducated participants (AOR = 5.04; 95% CI: 1.73\u201314.66;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.003). MA was significantly related to age (AOR = 29.83; 95% CI: 1.75\u2013508.3;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.019 for &amp;gt; 65 years old compared with 18\u201325 years old) and number of regular medications (AOR = 0.66; 95% CI: 0.44\u20130.99;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.044). A significant relationship was also observed between TS and the perception of having a mental illness and needing treatment (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001). PDR was significantly better among participants did not have to buy their own psychiatric medication compared with those who always purchased them (AOR = 5.04; 95% CI: 1.81\u201314.06;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.002) and among those with a history of using alternative methods compared with those without (AOR = 2.23; 95% CI: 1.21\u20134.11;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings highlight the interconnectedness of MA, TS, and PDR, as well as the influence of several factors. Patient-centered specific strategies are needed to address these factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyt.2025.1695769","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T10:27:06Z","timestamp":1768559226000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Medication adherence, treatment satisfaction, and patient\u2013doctor relationship in patients with mood disorders at a Saudi tertiary care hospital: a cross-sectional study"],"prefix":"10.3389","volume":"16","author":[{"given":"Ahmad H.","family":"Almadani","sequence":"first","affiliation":[{"name":"Department of Psychiatry, College of Medicine, King Saud University","place":["Riyadh, Saudi Arabia"]},{"name":"Department of Psychiatry, King Saud University Medical City, King Saud University","place":["Riyadh, Saudi Arabia"]},{"name":"SABIC Psychological Health Research and Applications Chair 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