{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T21:23:22Z","timestamp":1768512202127,"version":"3.49.0"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore the mediating mechanism of intrusive rumination between social support and non-suicidal self-injury (NSSI) behavior in patients with depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with depression admitted to our hospital from September 2023 to February 2024 were selected as the study subjects. A questionnaire survey was conducted using the General Information Questionnaire, Intrusive Rumination Scale, Perceived Social Support Scale, and Ottawa Self-Injury Inventory (OSI). Pearson correlation analysis and structural equation modeling (SEM) were used to test the mediating effect.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The scores for intrusive rumination, total social support, and NSSI behavior in 120 depressed patients were (15.71 \u00b1 2.13), (47.85 \u00b1 4.69), and (16.35 \u00b1 2.65), respectively. NSSI behavior was negatively correlated with the total social support score and its three dimensions (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.05), and positively correlated with the total intrusive rumination score (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.05). Intrusive rumination showed a mediating effect of 27.40% between social support and NSSI behavior.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Social support can influence NSSI behavior in depressed patients by regulating intrusive rumination. It is crucial to emphasize the assessment of intrusive rumination in clinical practice to reduce the occurrence of NSSI behavior.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyt.2025.1733769","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T06:27:59Z","timestamp":1768458479000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of the mediating effect of invasive ruminative contemplation on the relationship between social support and non-suicidal self-injury behavior in depressed patients"],"prefix":"10.3389","volume":"16","author":[{"given":"Mei","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Tao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ni","family":"Tao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-clinpsy-072220-021440","article-title":"Major depression and its recurrences: life course matters","volume":"9","author":"Monroe","year":"2022","journal-title":"Annu Rev Clin Psychol"},{"key":"B2","article-title":"The current situation and epidemiological characteristics of depression and anxiety of middle school students in hunan province","volume":"31","author":"Liu","year":"2023","journal-title":"Chin J Clin Psychol"},{"key":"B3","first-page":"281","article-title":"Mediating effect of rumination thinking between childhood maltreatment and depressive symptoms in patients with major depressive disorder","volume":"51","author":"Xing","year":"2022","journal-title":"Chongqing Med"},{"key":"B4","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/s12905-025-03580-y","article-title":"The mediating effect of intrusive rumination on the relationship between illness uncertainty and fear of cancer recurrence in breast cancer survivors","volume":"25","author":"T\u00fcrkel","year":"2025","journal-title":"BMC Womens Health"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.21037\/jgo-22-884","article-title":"Impact of caregiver burden on caregiver mental health in patients with esophageal cancer: chain mediating effects of benefit finding and rumination, a cross-sectional study","volume":"13","author":"Wen","year":"2022","journal-title":"J Gastrointest Oncol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/j.jad.2022.04.124","article-title":"The relationship between family functioning and non-suicidal self-injury in adolescents: A structural equation modeling analysis","volume":"15","author":"Wang","year":"2022","journal-title":"J Affect Disord"},{"key":"B7","article-title":"A systematic review of non-suicidal self-injury in adolescents with depression","volume":"29","author":"Li","year":"2020","journal-title":"Chin J Behav Med Brain Sci"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1111\/sltb.12747","article-title":"Examining decentering as a moderator in the relation between non-suicidal self-injury and suicide ideation via cognitive-affective factors","volume":"51","author":"Rosario-Williams","year":"2021","journal-title":"Suicide Life Threat Behav"},{"key":"B9","article-title":"Mediating effect of social support on depression and non-suicidal self-injury among medical students","volume":"40","author":"Huang","year":"2023","journal-title":"J Of Guangxi Med Univ"},{"key":"B10","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1186\/s12888-023-04754-4","article-title":"The role of depressive symptoms and social support in the association of internet addiction with non-suicidal self-injury among adolescents: a cohort study in China","volume":"23","author":"Ma","year":"2023","journal-title":". 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