{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T19:05:31Z","timestamp":1783796731496,"version":"3.55.0"},"reference-count":51,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:p>Severe mental illness (SMI) is used here as a functional and service-relevant category: mental disorders associated with substantial, persistent, or recurrent restrictions in major life activities, role participation, treatment stability, or safety. Psychotherapy in SMI requires more than symptom reduction. Clinicians must repeatedly decide whether to deepen emotional work, downshift to regulation, address avoidance, protect emerging progress, or intervene against shame-driven self-attack. These decisions are clinically central but often remain poorly documented and difficult to supervise, compare, or validate. This Hypothesis &amp;amp; Theory manuscript proposes an SMI-specific clinical translation of the Perceive-Assess-Dose-Safeguard (PAD-S) decision matrix and the related Conflict-Square Algorithm (CSA) as a sparse, human-final decision language for such moments. PAD-S\/CSA organizes session cues into four process nodes: Progression (PRO), Anxiety\/Affect tolerance (ANX), Defense\/Avoidance (DEF), and Superego\/Shame attack (SUP). Each node is linked to tolerance thresholds, calibrated therapist moves, safeguards, and expected functional impact. The framework connects three levels without collapsing them: the International Classification of Diseases, 11th Revision (ICD-11), together with the Clinical Descriptions and Diagnostic Requirements (CDDR), anchors diagnosis and severity context; the International Classification of Functioning, Disability and Health (ICF) and the Mini-ICF-APP rating for activity and participation restrictions in mental disorders anchor activity and participation; PAD-S\/CSA documents session-level process decisions. The manuscript clarifies novelty relative to related PAD-S\/CSA publications, defines SMI operationally, provides plain-language node definitions, gives an SMI-specific adaptation table, illustrates a worked micro-sequence and two brief vignettes, and proposes a staged validation agenda. Digital extensions are framed as optional annotation, summarization, and research support; clinical responsibility remains human-final.<\/jats:p>","DOI":"10.3389\/fpsyt.2026.1689702","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T15:50:03Z","timestamp":1782921003000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["From symptoms to function: the PAD-S decision matrix for severe mental illness\u2014a transdiagnostic clinical translation framework for ICD-11\/ICF-aligned psychotherapy documentation"],"prefix":"10.3389","volume":"17","author":[{"given":"Eik","family":"Niederlohmann","sequence":"first","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy","place":["Kliniken Erlabrunn, Breitenbrunn, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,1]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2026.1749364","article-title":"Perceive-assess-dose-safeguard: a safety-gated state-action grammar for psychotherapy micro-decisions in computational psychiatry","volume":"17","author":"Niederlohmann","year":"2026","journal-title":"Front Psychiatry"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2026.1687372","article-title":"A transdiagnostic conflict-square algorithm: a four-node computational framework for psychotherapy and functional diagnosis","volume":"17","author":"Niederlohmann","year":"2026","journal-title":"Front Psychiatry"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2026.1817747","article-title":"PAD-S\/CSA as a candidate shared representation layer for computational psychotherapy: minimal architecture and a staged validation roadmap","volume":"17","author":"Niederlohmann","year":"2026","journal-title":"Front Psychiatry"},{"key":"B4","volume-title":"Clinical descriptions and diagnostic requirements for ICD-11 mental, behavioural and neurodevelopmental disorders","year":"2024"},{"key":"B5","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/wps.20611","article-title":"Innovations and changes in the ICD-11 classification of mental, behavioural and neurodevelopmental disorders","volume":"18","author":"Reed","year":"2019","journal-title":"World Psychiatry"},{"key":"B6","volume-title":"International classification of functioning, disability and health (ICF)","year":"2001"},{"key":"B7","volume-title":"International Classification of Functioning, Disability and Health (ICF), browser release 2026-01","year":"2026"},{"key":"B8","article-title":"Mental illness: serious mental illness definition","year":""},{"key":"B9","article-title":"Serious mental illness and serious emotional disturbances","year":""},{"key":"B10","volume-title":"Mental disorders. 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