{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T06:06:46Z","timestamp":1784700406728,"version":"3.55.0"},"reference-count":51,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the relationships among perceived risk of recurrence, attitudes toward seeking professional psychological help, negative emotions, and family care in patients with ischemic stroke, and to test a moderated mediation model. The findings aim to provide a scientific basis for optimizing clinical psychological interventions and family support strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional survey was conducted among 311 patients with ischemic stroke recruited from three tertiary hospitals in Sichuan Province, China. Data were collected using validated scales measuring perceived recurrence risk, help-seeking attitudes, negative emotions, and family care. Mediation and moderated mediation analyses were performed using SPSS 27.0 and PROCESS macro (Models 4 and 58), with 5, 000 bootstrap resamples to estimate 95% confidence intervals (CIs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Perceived recurrence risk was positively associated with negative emotions (\n                      <jats:italic>\u03b2 = 0.350, p &amp;lt; 0.001<\/jats:italic>\n                      ). Attitudes toward seeking professional psychological help partially mediated this association, with a significant indirect effect (\n                      <jats:italic>effect = 0.131, 95% CI: 0.082\u20130.192<\/jats:italic>\n                      ), accounting for 40.68% of the total effect. Family care moderated both paths of the mediation model. In the first stage, family care moderated the association between perceived recurrence risk and help-seeking attitudes (\n                      <jats:italic>\u03b2 = 0.043, p = 0.001<\/jats:italic>\n                      ), such that higher family care weakened the negative association. In the second stage, family care moderated the association between help-seeking attitudes and negative emotions (\n                      <jats:italic>\u03b2 = \u22120.075, p = 0.008<\/jats:italic>\n                      ), indicating that higher family care strengthened the protective association between help-seeking attitudes and lower negative emotions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Perceived recurrence risk, help-seeking attitudes, and negative emotions are significantly associated in patients with ischemic stroke. Help-seeking attitudes partially explain this association, while family care plays a significant moderating role in both stages. These findings highlight the importance of psychological and family-centered support in stroke rehabilitation. However, causal interpretations should be made cautiously due to the cross-sectional design.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyt.2026.1865589","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T05:53:43Z","timestamp":1784699623000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Mechanisms underlying the association between perceived recurrence risk and negative emotions in patients with ischemic stroke: a cross-sectional study"],"prefix":"10.3389","volume":"17","author":[{"given":"Renlong","family":"Liang","sequence":"first","affiliation":[{"name":"Department of Neurology, Deyang Hospital Affiliated Hospital of Chengdu University of Traditional Chinese Medicine","place":["Deyang, Sichuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuyan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Nursing, Deyang People\u2019s Hospital","place":["Deyang, Sichuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Jian","sequence":"additional","affiliation":[{"name":"Department of Neurology, Deyang Hospital Affiliated Hospital of Chengdu University of Traditional Chinese Medicine","place":["Deyang, Sichuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Neurology, Deyang Hospital Affiliated Hospital of Chengdu University of Traditional Chinese Medicine","place":["Deyang, Sichuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Neurology, Deyang Hospital Affiliated Hospital of Chengdu University of Traditional Chinese Medicine","place":["Deyang, Sichuan, 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