{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:04:43Z","timestamp":1789538683976,"version":"build-2803163510"},"reference-count":31,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Depression and perceived stress are prevalent mental health problems worldwide, closely associated with physical health. Prior studies have suggested that both weight gain and loss may increase the odds of depression and stress, highlighting the need for clarification using national data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from the Korea National Health and Nutrition Examination Survey in 2014, 2016, 2018, and 2020 were used. The final analytic sample included 21,599 adults aged \u226519 years. We identified weight change over the past year and categorized it into seven groups (\u226510 kg loss, 6\u2013&amp;lt;10\u00a0kg loss, 3\u2013&amp;lt;6\u00a0kg loss, no weight change, 3\u2013&amp;lt;6\u00a0kg gain, 6\u2013&amp;lt;10\u00a0kg gain, and \u226510 kg gain). We analyzed the odds of depressive symptoms, self-reported physician diagnosis of depression, and perceived stress according to the change in weight.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Higher odds of depressive symptoms, self-reported physician diagnosis of depression, and perceived stress were observed at both substantial weight loss and weight gain. Compared with participants reporting no weight change, the adjusted odds ratios (95% CIs) for weight loss \u226510 kg were 3.51 (2.30\u20135.34), 1.99 (1.17\u20133.78), and 1.83 (1.34\u20132.48) for depressive symptoms, self-reported physician diagnosis of depression, and perceived stress, respectively. The corresponding estimates for weight gain \u226510 kg were 3.82 (2.72\u20135.36), 2.80 (1.89\u20134.14), and 2.28 (1.82\u20132.85), respectively. No significant interactions were observed between weight change and sex, age, body mass index, or weight control status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Substantial weight loss and weight gain were associated with elevated odds of adverse mental health outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpsyt.2026.1941947","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:31:32Z","timestamp":1789536692000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations of weight change with perceived stress and depression: a nationwide population-based study"],"prefix":"10.3389","volume":"17","author":[{"given":"Yujin","family":"Bae","sequence":"first","affiliation":[{"name":"Department of Psychology, Ewha Womans University","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye-Seul","family":"Song","sequence":"additional","affiliation":[{"name":"Big Data Center, Doheon Institute for Digital Innovation in Medicine, Hallym University Medical Center, Anyang","place":["Gyeonggi-do, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Hee","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital","place":["Anyang, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Ju","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital","place":["Anyang, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyewon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, College of Medicine, Hallym University, Hallym University Sacred Heart Hospital","place":["Anyang, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"B1","volume-title":"Depression and Other Common Mental Disorders: Global Health Estimates","year":"2017"},{"key":"B2","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1001\/archpsyc.62.6.593","article-title":"Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication","volume":"62","author":"Kessler","year":"2005","journal-title":"Arch Gen Psychiatry"},{"key":"B3","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1017\/S0033291709991036","article-title":"How common are common mental disorders? 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