{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:12:40Z","timestamp":1793707960308,"version":"4.6.1"},"reference-count":114,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    The EQ-5D-5L is a generic preference-based questionnaire developed by the EuroQol Group to measure health-related quality of life (HRQoL) in 2005. Since its development, it has been increasingly applied in populations with various diseases and has been found to have good reliability and sensitivity. This study aimed to summarize the health utility elicited from EQ-5D-5L for patients with different diseases in cross-sectional studies worldwide.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    Web of Science, MEDLINE, EMBASE, and the Cochrane Library were searched from January 1, 2012, to October 31, 2019. Cross-sectional studies reporting utility values measured with the EQ-5D-5L in patients with any specific disease were eligible. The language was limited to English. Reference lists of the retrieved studies were manually searched to identify more studies that met the inclusion criteria. Methodological quality was assessed with the Agency for Health Research and Quality (AHRQ) checklist. In addition, meta-analyses were performed for utility values of any specific disease reported in three or more studies.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    In total, 9,400 records were identified, and 98 studies met the inclusion criteria. In the included studies, 50 different diseases and 98,085 patients were analyzed. Thirty-five studies involving seven different diseases were included in meta-analyses. The health utility ranged from 0.31 to 0.99 for diabetes mellitus [meta-analysis random-effect model (REM): 0.83, (95% CI = 0.77\u20130.90); fixed-effect model (FEM): 0.93 (95% CI = 0.93\u20130.93)]; from 0.62 to 0.90 for neoplasms [REM: 0.75 (95% CI = 0.68\u20130.82); FEM: 0.80 (95% CI = 0.78\u20130.81)]; from 0.56 to 0.85 for cardiovascular disease [REM: 0.77 (95% CI = 0.75\u20130.79); FEM: 0.76 (95% CI = 0.75\u20130.76)]; from 0.31 to 0.78 for multiple sclerosis [REM: 0.56 (95% CI = 0.47\u20130.66); FEM: 0.67 (95% CI = 0.66\u20130.68)]; from 0.68 to 0.79 for chronic obstructive pulmonary disease [REM: 0.75 (95% CI = 0.71\u20130.80); FEM: 0.76 (95% CI = 0.75\u20130.77)] from 0.65 to 0.90 for HIV infection [REM: 0.84 (95% CI = 0.80\u20130.88); FEM: 0.81 (95% CI = 0.80\u20130.82)]; from 0.37 to 0.89 for chronic kidney disease [REM: 0.70 (95% CI = 0.48\u20130.92; FEM: 0.76 (95% CI = 0.74\u20130.78)].\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    EQ-5D-5L is one of the most widely used preference-based measures of HRQoL in patients with different diseases worldwide. The variation of utility values for the same disease was influenced by the characteristics of patients, the living environment, and the EQ-5D-5L value set.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Systematic Review Registration<\/jats:bold>\n                    :\n                    <jats:ext-link>https:\/\/www.crd.york.ac.uk\/PROSPERO\/<\/jats:ext-link>\n                    , identifier CRD42020158694.\n                  <\/jats:p>","DOI":"10.3389\/fpubh.2021.675523","type":"journal-article","created":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T01:05:12Z","timestamp":1624928712000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":220,"title":["Health-Related Quality of Life in Patients With Different Diseases Measured With the EQ-5D-5L: A Systematic Review"],"prefix":"10.3389","volume":"9","author":[{"given":"Ting","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijing","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingjun","family":"Rui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aixia","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,6,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.jval.2019.01.004","article-title":"Identification, review, and use of health state utilities in cost-effectiveness models: an ISPOR good practices for outcomes research task force report","volume":"22","author":"Brazier","year":"2019","journal-title":"Value Health."},{"key":"B2","doi-asserted-by":"publisher","first-page":"337","DOI":"10.3109\/07853890109002087","article-title":"EQ-5D: a measure of health status from the EuroQol Group","volume":"33","author":"Rabin","year":"2001","journal-title":"Ann Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/S0167-6296(01)00130-8","article-title":"The estimation of a preference-based measure of health from the SF-36","volume":"21","author":"Brazier","year":"2002","journal-title":"J Health Econ."},{"key":"B4","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/1477-7525-1-54","article-title":"The Health Utilities Index (HUI): concepts, measurement properties and applications","volume":"1","author":"Horsman","year":"2003","journal-title":"Health Qual Life Outcomes."},{"key":"B5","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1016\/j.jval.2012.05.003","article-title":"Using health state utility values in models exploring the cost-effectiveness of health technologies","volume":"15","author":"Ara","year":"2012","journal-title":"Value Health."},{"key":"B6","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/j.jval.2016.06.001","article-title":"Estimating health-state utility for economic models in clinical studies: an ISPOR good research practices task force report","volume":"19","author":"Wolowacz","year":"2016","journal-title":"Value Health."},{"key":"B7","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1007\/s40273-014-0136-z","article-title":"Estimating QALY gains in applied studies: a review of cost-utility analyses published in 2010","volume":"32","author":"Wisl\u00f8ff","year":"2014","journal-title":"Pharmacoeconomics."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1007\/s11136-011-9903-x","article-title":"Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L)","volume":"20","author":"Herdman","year":"2011","journal-title":"Qual Life Res."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1007\/s11136-011-0018-1","article-title":"Comparing the psychometric properties of the EQ-5D-3L and EQ-5D-5L in cancer patients in Korea","volume":"21","author":"Kim","year":"2012","journal-title":"Qual Life Res."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1007\/s11136-012-0318-0","article-title":"Comparing the performance of the standard EQ-5D 3L with the new version EQ-5D 5L in patients with chronic hepatic diseases","volume":"22","author":"Scalone","year":"2013","journal-title":"Qual Life Res."},{"key":"B11","unstructured":"EQ-5D-5L User Guide2019"},{"key":"B12","unstructured":"EuroQolGroup\n          EQ-5D-5L Valuation: Standard Value Sets"},{"key":"B13","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1016\/j.jval.2012.02.008","article-title":"Interim scoring for the EQ-5D-5L: mapping the EQ-5D-5L to EQ-5D-3L value sets","volume":"15","author":"van Hout","year":"2012","journal-title":"Value Health."},{"key":"B14","doi-asserted-by":"publisher","first-page":"92","DOI":"10.22159\/ijap.2018.v10s1.19","article-title":"Cross-sectional study of association between glycemic control and quality of life among diabetic patients","volume":"10","author":"Natasya","year":"2018","journal-title":"Int J Pharmaceut"},{"key":"B15","doi-asserted-by":"publisher","first-page":"35","DOI":"10.2147\/DMSO.S154304","article-title":"Decreased health-related quality of life in patients with diabetic foot problems","volume":"11","author":"Sothornwit","year":"2018","journal-title":"Diabetes Metab Syndr Obes"},{"key":"B16","doi-asserted-by":"publisher","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med."},{"key":"B17","unstructured":"Methods guide for effectiveness and comparative effectiveness reviewsMethods Guide for Effectiveness and Comparative Effectiveness Reviews2008"},{"key":"B18","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1007\/s11136-018-1876-6","article-title":"Diabetic retinopathy and health-related quality of life among Chinese with known type 2 diabetes mellitus","volume":"27","author":"Pan","year":"2018","journal-title":"Qual Life Res."},{"key":"B19","doi-asserted-by":"publisher","first-page":"1801","DOI":"10.1007\/s11136-018-1840-5","article-title":"Do country-specific preference weights matter in the choice of mapping algorithms? The case of mapping the Diabetes-39 onto eight country-specific EQ-5D-5L value sets","volume":"27","author":"Lamu","year":"2018","journal-title":"Qual Life Res."},{"key":"B20","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1007\/s41669-017-0056-x","article-title":"Evaluation of health status of type 2 diabetes outpatients receiving care in a tertiary hospital in Nigeria","volume":"2","author":"Adibe","year":"2018","journal-title":"Pharmacoecon Open."},{"key":"B21","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1007\/s11136-019-02105-z","article-title":"Health-related quality of life in Indonesian type 2 diabetes mellitus outpatients measured with the Bahasa version of EQ-5D","volume":"28","author":"Arifin","year":"2019","journal-title":"Qual Life Res."},{"key":"B22","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/j.jdiacomp.2018.01.005","article-title":"Measurement of psychological adjustment to diabetes with the diabetes acceptance scale","volume":"32","author":"Schmitt","year":"2018","journal-title":"J Diabetes Complications."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.3305\/nh.2015.32.4.9605","article-title":"Normative values of EQ-5D-5L for diabetes patients from Spain","volume":"32","author":"Collado Mateo","year":"2015","journal-title":"Nutr Hosp."},{"key":"B24","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/s12882-018-0849-x","article-title":"Quality of life in hemodialysis diabetic patients: a multicenter cross-sectional study from Palestine","volume":"19","author":"Khatib","year":"2018","journal-title":"BMC Nephrol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.jcte.2015.03.002","article-title":"Relationship of treatment satisfaction to health-related quality of life among Palestinian patients with type 2 diabetes mellitus: findings from a cross-sectional study","volume":"2","author":"Zyoud","year":"2015","journal-title":"J Clin Transl Endocrinol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1093\/intqhc\/mzx067","article-title":"The relationship between shared decision-making and health-related quality of life among patients in Hong Kong SAR, China","volume":"29","author":"Xu","year":"2017","journal-title":"Int J Qual Health Care."},{"key":"B27","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1177\/0272989X15606903","article-title":"Valuing health-related quality of life in type 2 diabetes patients in China","volume":"36","author":"Pan","year":"2016","journal-title":"Med Decis Making."},{"key":"B28","doi-asserted-by":"publisher","first-page":"e022711","DOI":"10.1136\/bmjopen-2018-022711","article-title":"Assessing health-related quality of life of patients with colorectal cancer using EQ-5D-5L: a cross-sectional study in Heilongjiang of China","volume":"8","author":"Huang","year":"2018","journal-title":"BMJ Open."},{"key":"B29","doi-asserted-by":"publisher","first-page":"e012952","DOI":"10.1136\/bmjopen-2016-012952","article-title":"Effect of investigation intensity and treatment differences on prostate cancer survivor's physical symptoms, psychological well-being and health-related quality of life: a two country cross-sectional study","volume":"6","author":"Gavin","year":"2016","journal-title":"BMJ Open."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1016\/j.jval.2015.08.012","article-title":"Health-related quality of life and health utilities in metastatic castrate-resistant prostate cancer: A Survey capturing experiences from a diverse sample of UK patients","volume":"18","author":"Lloyd","year":"2015","journal-title":"Value Health."},{"key":"B31","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1111\/jdv.14703","article-title":"Patient-reported health outcomes in patients with non-melanoma skin cancer and actinic keratosis: results from a large-scale observational study analysing effects of diagnoses and disease progression","volume":"32","author":"Philipp-Dormston","year":"2018","journal-title":"J Eur Acad Dermatol Venereol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1001\/jamaoto.2015.1314","article-title":"Comparison of health state utility measures in patients with head and neck cancer","volume":"141","author":"Noel","year":"2015","journal-title":"JAMA Otolaryngol Head Neck Surg."},{"key":"B33","doi-asserted-by":"publisher","first-page":"e4","DOI":"10.2196\/ijmr.9325","article-title":"The patient perspective on the impact of tenosynovial giant cell tumors on daily living: crowdsourcing study on physical function and quality of life","volume":"7","author":"Mastboom","year":"2018","journal-title":"Interact J Med Res."},{"key":"B34","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1111\/ene.13786","article-title":"Patient-reported outcomes are worse for progressive-onset multiple sclerosis than relapse-onset multiple sclerosis, particularly early in the disease process","volume":"26","author":"Zhang","year":"2019","journal-title":"Eur J Neurol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"261","DOI":"10.17712\/nsj.2017.4.20170273","article-title":"Quality of life among multiple sclerosis patients in Saudi Arabia","volume":"22","author":"Algahtani","year":"2017","journal-title":"Neurosciences"},{"key":"B36","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.1177\/1352458512474860","article-title":"Relating health-related quality of life to disability progression in multiple sclerosis, using the 5-level EQ-5D","volume":"19","author":"Fogarty","year":"2013","journal-title":"Mult Scler."},{"key":"B37","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1080\/13696998.2018.1427100","article-title":"Societal costs of multiple sclerosis in Ireland","volume":"21","author":"Carney","year":"2018","journal-title":"J Med Econ."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1080\/13696998.2017.1373653","article-title":"The burden of multiple sclerosis in Japan","volume":"20","author":"Nohara","year":"2017","journal-title":"J Med Econ."},{"key":"B39","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.msard.2018.07.013","article-title":"The disease burden of Multiple sclerosis from the individual and population perspective: which symptoms matter most?","volume":"25","author":"Barin","year":"2018","journal-title":"Mult Scler Relat Disord."},{"key":"B40","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.resuscitation.2014.12.021","article-title":"Cognitive function and health-related quality of life four years after cardiac arrest","volume":"89","author":"Buanes","year":"2015","journal-title":"Resuscitation."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jpsychores.2017.01.003","article-title":"DenHeart: differences in physical and mental health across cardiac diagnoses at hospital discharge","volume":"94","author":"Berg","year":"2017","journal-title":"J Psychosom Res."},{"key":"B42","doi-asserted-by":"publisher","first-page":"30","DOI":"10.5837\/bjc.2017.007","article-title":"Impact of HF on HRQoL in patients and their caregivers in England: results from the ASSESS study","volume":"24","author":"Squire","year":"2017","journal-title":"Br J Cardiol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/j.rec.2016.10.004","article-title":"Iron deficiency is a determinant of functional capacity and health-related quality of life 30 days after an acute coronary syndrome","volume":"70","author":"Mero\u00f1o","year":"2017","journal-title":"Rev Esp Cardiol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"2643814","DOI":"10.1155\/2018\/2643814","article-title":"Socioeconomic inequalities in health-related quality of life among patients with cardiovascular diseases in Vietnam","volume":"2018","author":"Tran","year":"2018","journal-title":"Biomed Res Int."},{"key":"B45","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/j.amjcard.2018.05.015","article-title":"The disease burden of atrial fibrillation in China from a national cross-sectional survey","volume":"122","author":"Wang","year":"2018","journal-title":"Am J Cardiol"},{"key":"B46","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1177\/2047487315604837","article-title":"Validity and reliability of the HeartQoL questionnaire in a large sample of stable coronary patients: The EUROASPIRE IV Study of the European Society of Cardiology","volume":"23","author":"De Smedt","year":"2016","journal-title":"Eur J Prev Cardiol."},{"key":"B47","first-page":"1046","article-title":"A cross-sectional assessment of health-related quality of life among patients with chronic obstructive pulmonary disease","volume":"46","author":"Garcia-Gordillo","year":"2017","journal-title":"Iran J Public Health."},{"key":"B48","doi-asserted-by":"publisher","first-page":"2629","DOI":"10.2147\/COPD.S167476","article-title":"COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan","volume":"13","author":"Igarashi","year":"2018","journal-title":"Int J Chron Obstruct Pulmon Dis."},{"key":"B49","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1186\/1471-2288-14-78","article-title":"Measuring health-related quality of life in chronic obstructive pulmonary disease: properties of the EQ-5D-5L and PROMIS-43 short form","volume":"14","author":"Lin","year":"2014","journal-title":"BMC Med Res Methodol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1136\/thoraxjnl-2015-207782","article-title":"The EQ-5D-5L health status questionnaire in COPD: validity, responsiveness and minimum important difference","volume":"71","author":"Nolan","year":"2016","journal-title":"Thorax."},{"key":"B51","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.vhri.2016.05.001","article-title":"Health-related quality of life of patients with HIV\/AIDS in Bogot\u00e1, Colombia","volume":"11","author":"Keaei","year":"2016","journal-title":"Value Health Reg Issues."},{"key":"B52","doi-asserted-by":"publisher","first-page":"e020688","DOI":"10.1136\/bmjopen-2017-020688","article-title":"Physical activity among HIV-positive patients receiving antiretroviral therapy in Hanoi and Nam Dinh, Vietnam: a cross-sectional study","volume":"8","author":"Dang","year":"2018","journal-title":"BMJ Open."},{"key":"B53","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1186\/1477-7525-10-132","article-title":"Quality of life profile and psychometric properties of the EQ-5D-5L in HIV\/AIDS patients","volume":"10","author":"Tran","year":"2012","journal-title":"Health Qual Life Outcomes."},{"key":"B54","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1080\/14737167.2017.1246185","article-title":"The impact of comorbidities on costs, utilities and health-related quality of life among HIV patients in a clinical setting in Bogot\u00e1","volume":"17","author":"Van Duin","year":"2017","journal-title":"Expert Rev Pharmacoecon Outcomes Res."},{"key":"B55","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1007\/s10198-014-0664-7","article-title":"Comparison of the preference-based EQ-5D-5L and SF-6D in patients with end-stage renal disease (ESRD)","volume":"16","author":"Yang","year":"2015","journal-title":"Eur J Health Econ."},{"key":"B56","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/j.transproceed.2019.01.049","article-title":"Estimating the net utility gains among donors and recipients of adult living donor kidney transplant","volume":"51","author":"Hiragi","year":"2019","journal-title":"Transplant Proc."},{"key":"B57","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1186\/s12882-016-0257-z","article-title":"Factors affecting quality of life in patients on haemodialysis: a cross-sectional study from Palestine","volume":"17","author":"Zyoud","year":"2016","journal-title":"BMC Nephrol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"3336","DOI":"10.1111\/hex.12324","article-title":"Relationship of treatment satisfaction to health-related quality of life: findings from a cross-sectional survey among hypertensive patients in Palestine","volume":"18","author":"Al-Jabi","year":"2015","journal-title":"Health Expect."},{"key":"B59","doi-asserted-by":"publisher","first-page":"2778","DOI":"10.1016\/j.injury.2017.10.032","article-title":"Plating for midshaft clavicular fractures: the impact on quality of life and functional outcome","volume":"48","author":"van der Linde","year":"2017","journal-title":"Injury."},{"key":"B60","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1007\/s00068-014-0488-2","article-title":"Decreased muscle strength is associated with impaired long-term functional outcome after intramedullary nailing of femoral shaft fracture","volume":"41","author":"Larsen","year":"2015","journal-title":"Eur J Trauma Emerg Surg."},{"key":"B61","doi-asserted-by":"publisher","first-page":"317","DOI":"10.3349\/ymj.2018.59.2.317","article-title":"Prevalence of frailty in patients with osteoporotic vertebral compression fracture and its association with numbers of fractures","volume":"59","author":"Kim","year":"2018","journal-title":"Yonsei Med J."},{"key":"B62","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1111\/jir.12288","article-title":"Economic burden and health-related quality of life associated with Prader-Willi syndrome in France","volume":"60","author":"Chevreul","year":"2016","journal-title":"J Intellect Disabil Res."},{"key":"B63","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s10198-016-0788-z","article-title":"Social\/economic costs and health-related quality of life in patients with Prader-Willi syndrome in Europe","volume":"17","author":"L\u00f3pez-Bastida","year":"2016","journal-title":"Eur J Health Econ."},{"key":"B64","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1136\/flgastro-2013-100409","article-title":"Disease status, patient quality of life and healthcare resource use for ulcerative colitis in the UK: an observational study","volume":"5","author":"Vaizey","year":"2014","journal-title":"Frontline Gastroenterol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/j.crohns.2013.11.017","article-title":"Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: a cross-sectional, observational study","volume":"8","author":"Gibson","year":"2014","journal-title":"J Crohns Colitis."},{"key":"B66","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1007\/s00403-017-1743-2","article-title":"Assessment of the psychometric properties of the EQ-5D-3L and EQ-5D-5L instruments in psoriasis","volume":"309","author":"Yfantopoulos","year":"2017","journal-title":"Arch Dermatol Res."},{"key":"B67","doi-asserted-by":"publisher","first-page":"e7840","DOI":"10.1097\/MD.0000000000007840","article-title":"Does the choice of tariff matter?: a comparison of EQ-5D-5L utility scores using Chinese, UK, and Japanese tariffs on patients with psoriasis vulgaris in Central South China","volume":"96","author":"Zhao","year":"2017","journal-title":"Medicine."},{"key":"B68","doi-asserted-by":"publisher","first-page":"3077","DOI":"10.1007\/s10067-018-4125-z","article-title":"Association of neuropathic-like pain characteristics with clinical and radiographic features in patients with ankylosing spondylitis","volume":"37","author":"Choi","year":"2018","journal-title":"Clin Rheumatol."},{"key":"B69","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1097\/RHU.0000000000000750","article-title":"Relationship between health-related quality of life and patient acceptable symptom state with disease activity and functional status in patients with ankylosing spondylitis in Thailand","volume":"25","author":"Chiowchanwisawakit","year":"2019","journal-title":"J Clin Rheumatol"},{"key":"B70","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.jns.2015.08.010","article-title":"Convergent validation of EQ-5D-5L in patients with Parkinson's disease","volume":"358","author":"Alvarado-Bola\u00f1os","year":"2015","journal-title":"J Neurol Sci."},{"key":"B71","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1007\/s11136-013-0569-4","article-title":"Validation and comparison of 15-D and EQ-5D-5L instruments in a Spanish Parkinson's disease population sample","volume":"23","author":"Garc\u00eda-Gordillo","year":"2014","journal-title":"Qual Life Res."},{"key":"B72","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/s12955-015-0274-9","article-title":"Impact of overactive bladder on quality of life and resource use: results from Korean Burden of Incontinence Study (KOBIS)","volume":"13","author":"Lee","year":"2015","journal-title":"Health Qual Life Outcomes."},{"key":"B73","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/2051415817710111","article-title":"The impact of age, gender and severity of overactive bladder wet on quality of life, productivity, treatment patterns and satisfaction","volume":"10","author":"Lloyd","year":"2017","journal-title":"J Clin Urol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"447","DOI":"10.2500\/aap.2017.38.4087","article-title":"Health-related quality of life in relation to disease activity in adults with hereditary angioedema in Sweden","volume":"38","author":"Nordenfelt","year":"2017","journal-title":"Allergy Asthma Proc."},{"key":"B75","doi-asserted-by":"publisher","first-page":"185","DOI":"10.2500\/aap.2014.35.3738","article-title":"Quantifying the burden of disease and perceived health state in patients with hereditary angioedema in Sweden","volume":"35","author":"Nordenfelt","year":"2014","journal-title":"Allergy Asthma Proc."},{"key":"B76","doi-asserted-by":"publisher","first-page":"2481","DOI":"10.1007\/s11136-016-1297-3","article-title":"Health state descriptions, valuations and individuals' capacity to walk: a comparative evaluation of preference-based instruments in the context of spinal cord injury","volume":"25","author":"Whitehurst","year":"2016","journal-title":"Qual Life Res."},{"key":"B77","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.socscimed.2018.07.041","article-title":"Using path analysis to investigate the relationships between standardized instruments that measure health-related quality of life, capability well-being and subjective well-being: an application in the context of spinal cord injury","volume":"213","author":"Engel","year":"2018","journal-title":"Soc Sci Med."},{"key":"B78","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1111\/ejh.13055","article-title":"Impact of hemophilia B on quality of life in affected men, women, and caregivers-Assessment of patient-reported outcomes in the B-HERO-S study","volume":"100","author":"Buckner","year":"2018","journal-title":"Eur J Haematol."},{"key":"B79","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1111\/hae.13377","article-title":"Impact of pain and functional impairment in US adults with haemophilia: patient-reported outcomes and musculoskeletal evaluation in the pain, functional impairment and quality of life (P-FiQ) study","volume":"24","author":"Kempton","year":"2018","journal-title":"Haemophilia."},{"key":"B80","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.ejpsy.2017.11.001","article-title":"Determinants of quality of life in Spanish outpatients with schizophrenia spectrum disorders","volume":"32","author":"Arraras","year":"2017","journal-title":"Eur J Psychiat."},{"key":"B81","doi-asserted-by":"publisher","first-page":"5","DOI":"10.15557\/PiPK.2018.0001","article-title":"Quality of life in institutionalized patients with schizophrenia","volume":"18","author":"Kitic","year":"2018","journal-title":"Psychiatr Psychol Klin."},{"key":"B82","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/s12955-015-0295-4","article-title":"Health related quality of life in patients with actinic keratosis\u2013an observational study of patients treated in dermatology specialist care in Denmark","volume":"13","author":"Tennvall","year":"2015","journal-title":"Health Qual Life Outcomes."},{"key":"B83","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1016\/j.jval.2017.09.017","article-title":"Development of methods for the mapping of utilities using mixture models: mapping the AQLQ-S to the EQ-5D-5L and the HUI3 in patients with asthma","volume":"21","author":"Gray","year":"2018","journal-title":"Value Health."},{"key":"B84","doi-asserted-by":"publisher","first-page":"e0202624","DOI":"10.1371\/journal.pone.0202624","article-title":"Impact of asthma on women and men: comparison with the general population using the EQ-5D-5L questionnaire","volume":"13","author":"Hernandez","year":"2018","journal-title":"PLoS ONE."},{"key":"B85","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1002\/hep.30031","article-title":"The impact of autoimmune hepatitis and its treatment on health utility","volume":"68","author":"Wong","year":"2018","journal-title":"Hepatology."},{"key":"B86","doi-asserted-by":"publisher","first-page":"61","DOI":"10.3389\/fmed.2019.00061","article-title":"The patient perspectives on future therapeutic options in nash and patient needs","volume":"6","author":"Cook","year":"2019","journal-title":"Front Med."},{"key":"B87","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/j.jval.2016.05.008","article-title":"Which questionnaire should be used to measure quality-of-life utilities in patients with acute leukemia? An evaluation of the validity and interpretability of the EQ-5D-5L and preference-based questionnaires derived from the EORTC QLQ-C30","volume":"19","author":"van","year":"2016","journal-title":"Value Health."},{"key":"B88","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/1750-1172-9-32","article-title":"Burden of disease in patients with Morquio A syndrome: results from an international patient-reported outcomes survey","volume":"9","author":"Hendriksz","year":"2014","journal-title":"Orphanet J Rare Dis."},{"key":"B89","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1080\/13696998.2016.1211136","article-title":"Assessing the impact of nocturia on health-related quality-of-life and utility: results of an observational survey in adults","volume":"19","author":"Andersson","year":"2016","journal-title":"J Med Econ."},{"key":"B90","doi-asserted-by":"publisher","first-page":"129","DOI":"10.7224\/1537-2073.2017-076","article-title":"Assessment of patients with neuromyelitis optica spectrum disorder using the EQ-5D","volume":"21","author":"Mealy","year":"2019","journal-title":"Int J MS Care."},{"key":"B91","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1002\/acr.23468","article-title":"Association of comorbidities in spondyloarthritis with poor function, work disability, and quality of life: results from the assessment of spondyloarthritis international society comorbidities in spondyloarthritis study","volume":"70","author":"Nikiphorou","year":"2018","journal-title":"Arthritis Care Res."},{"key":"B92","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1016\/j.dld.2016.01.011","article-title":"Burden of disease and patient-reported outcomes in patients with moderate to severe ulcerative colitis in the last 12 months - Multicenter European cohort study","volume":"48","author":"Van Assche","year":"2016","journal-title":"Dig Liver Dis."},{"key":"B93","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.eurger.2015.12.011","article-title":"Burden-of-illness of Dutch community-dwelling older adults with sarcopenia: health related outcomes and costs","volume":"7","author":"Mijnarends","year":"2016","journal-title":"Eur Geriatr Med."},{"key":"B94","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.3390\/ijerph15061174","article-title":"Cost-of-illness and the health-related quality of life of patients in the dengue fever outbreak in Hanoi in 2017","volume":"15","author":"Tran","year":"2018","journal-title":"Int J Environ Res Public Health."},{"key":"B95","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/j.jcf.2014.11.006","article-title":"Costs and health-related quality of life of patients with cystic fibrosis and their carers in France","volume":"14","author":"Chevreul","year":"2015","journal-title":"J Cyst Fibros"},{"key":"B96","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1186\/s12955-017-0690-0","article-title":"Fibromyalgia and quality of life: mapping the revised fibromyalgia impact questionnaire to the preference-based instruments","volume":"15","author":"Collado-Mateo","year":"2017","journal-title":"Health Qual Life Outcomes"},{"key":"B97","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1111\/jir.12215","article-title":"Fragile X syndrome: economic burden and health-related quality of life of patients and caregivers in France","volume":"59","author":"Chevreul","year":"2015","journal-title":"J Intellect Disabil Res."},{"key":"B98","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1186\/s12891-017-1595-0","article-title":"Generalised joint hypermobility and shoulder joint hypermobility, - risk of upper body musculoskeletal symptoms and reduced quality of life in the general population","volume":"18","author":"Juul-Kristensen","year":"2017","journal-title":"BMC Musculoskelet Disord."},{"key":"B99","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1111\/coa.12903","article-title":"Health utility reporting in chronic rhinosinusitis patients","volume":"43","author":"Bewick","year":"2018","journal-title":"Clin Otolaryngol."},{"key":"B100","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/s13023-016-0538-4","article-title":"Health-related quality of life and a cost-utility simulation of adults in the UK with osteogenesis imperfecta, X-linked hypophosphatemia and fibrous dysplasia","volume":"11","author":"Forestier-Zhang","year":"2016","journal-title":"Orphanet J Rare Dis."},{"key":"B101","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s41927-019-0080-9","article-title":"Health-related quality of life in patients with rheumatoid arthritis","volume":"3","author":"Katchamart","year":"2019","journal-title":"BMC Rheumatol."},{"key":"B102","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1007\/s10067-019-04485-6","article-title":"Health-related quality of life in patients with systemic lupus erythematosus: a Spanish study based on patient reports","volume":"38","author":"Rom\u00e1n Ivorra","year":"2019","journal-title":"Clin Rheumatol."},{"key":"B103","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s11136-015-1065-9","article-title":"How does the EQ-5D perform when measuring quality of life in dementia against two other dementia-specific outcome measures?","volume":"25","author":"Aguirre","year":"2016","journal-title":"Qual Life Res."},{"key":"B104","doi-asserted-by":"publisher","first-page":"e0175847","DOI":"10.1371\/journal.pone.0175847","article-title":"Mapping the SRS-22r questionnaire onto the EQ-5D-5L utility score in patients with adolescent idiopathic scoliosis","volume":"12","author":"Wong","year":"2017","journal-title":"PLoS ONE."},{"key":"B105","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.sjpain.2015.12.007","article-title":"Opioid-induced constipation, use of laxatives, and health-related quality of life","volume":"11","author":"Christensen","year":"2016","journal-title":"Scand J Pain."},{"key":"B106","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1186\/s10194-018-0907-6","article-title":"Patients' perspective on the burden of migraine in Europe: a cross-sectional analysis of survey data in France, Germany, Italy, Spain, and the United Kingdom","volume":"19","author":"Vo","year":"2018","journal-title":"J Headache Pain."},{"key":"B107","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1080\/02699052.2019.1607557","article-title":"Prevalence of post-concussion-like symptoms in the general population in Italy, The Netherlands and the United Kingdom","volume":"33","author":"Voormolen","year":"2019","journal-title":"Brain Inj."},{"key":"B108","doi-asserted-by":"publisher","first-page":"E42","DOI":"10.1097\/NCC.0000000000000411","article-title":"Psychometric properties of the Chinese version of the acceptance of Chronic Health Conditions (Stoma) Scale for patients with stoma","volume":"40","author":"Lim","year":"2017","journal-title":"Cancer Nurs."},{"key":"B109","doi-asserted-by":"publisher","first-page":"145","DOI":"10.2147\/PROM.S101595","article-title":"Quality of life and use of health care resources among patients with chronic depression","volume":"7","author":"Villoro","year":"2016","journal-title":"Patient Relat Outcome Meas."},{"key":"B110","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1111\/eos.12290","article-title":"The burden of disease of dental anxiety: generic and disease-specific quality of life in patients with and without extreme levels of dental anxiety","volume":"124","author":"Vermaire","year":"2016","journal-title":"Eur J Oral Sci."},{"key":"B111","doi-asserted-by":"publisher","first-page":"1648","DOI":"10.1002\/bjs.10598","article-title":"Truncal varicose vein diameter and patient-reported outcome measures","volume":"104","author":"Lane","year":"2017","journal-title":"Br J Surg."},{"key":"B112","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1007\/s11136-018-2003-4","article-title":"Validity of the EQ-5D-5L and EQ-5D-3L in patients with Crohn's disease","volume":"28","author":"Rencz","year":"2019","journal-title":"Qual Life Res."},{"key":"B113","doi-asserted-by":"publisher","first-page":"238","DOI":"10.3109\/03009742.2014.976653","article-title":"The economic burden and health-related quality of life associated with systemic sclerosis in France","volume":"44","author":"Chevreul","year":"2015","journal-title":"Scand J Rheumatol"},{"key":"B114","unstructured":"Position Statement on Use of the EQ-5D-5L Value Set for England (updated October 2019)"}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2021.675523\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T01:05:18Z","timestamp":1624928718000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2021.675523\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,29]]},"references-count":114,"alternative-id":["10.3389\/fpubh.2021.675523"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2021.675523","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,29]]},"article-number":"675523"}}