{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:20:09Z","timestamp":1756462809323,"version":"3.41.2"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T00:00:00Z","timestamp":1641254400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:p>Cancer research is deficient in Colombia and efforts and resources diverted due to the COVID-19 pandemic could worsen the situation. We explore the impact of the pandemic on cancer research funding, output, and conduct. We sought information at national level and used the experience of an academic reference center to contrast the impact at institutional level. We searched databases and official documents of national governmental institutions, trial registries, hospital registries, and the Web of Science. We interviewed principal investigators (PIs) to retrieve information on the conduct of cancer research. A decline in resource availability and new proposals was observed at the national level with a shift to COVID-19 related research. However, at institutional level there was no decline in the number of cancer research proposals. The predominance of observational studies as opposed to the preponderance of clinical trials and basic science in high-income countries may be related to the lower impact at institutional level. Nevertheless, we found difficulties similar to previous reports for conducting research during the pandemic. PIs reported long recovery times and a great impact on research other than clinical trials, such as observational and qualitative studies. No significant impact on research output was observed. Alternatives to ensure research continuity such as telemedicine and remote data collection have scarcely been implemented given limited access and low technology literacy. In this middle-income setting the situation shows a notable dependency of international collaborations to develop research on COVID-19 and cancer and to overcome challenges for cancer research during the pandemic.<\/jats:p>","DOI":"10.3389\/fpubh.2021.750755","type":"journal-article","created":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T08:05:02Z","timestamp":1641283502000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Cancer Research in the Time of COVID-19: A Colombian Narrative"],"prefix":"10.3389","volume":"9","author":[{"given":"Ra\u00fal","family":"Murillo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ginna","family":"Fern\u00e1ndez-Deaza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Zuluaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grant","family":"Lewison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Usgame-Zubieta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iv\u00e1n Dar\u00edo","family":"Usgame-Zubieta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Margarita","family":"Manrique","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,1,4]]},"reference":[{"key":"B1","unstructured":"2021"},{"key":"B2","doi-asserted-by":"publisher","first-page":"s21","DOI":"10.5530\/jscires.10.1s.19","article-title":"Cancer research in Latin America, 2014\u20132019, and its disease burden","volume":"10","author":"Lewison","year":"2021","journal-title":"J Scientometr Res"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1200\/JGO.19.00164","article-title":"Scientific productivity and cancer-related mortality: a case study of a positive association in colombia","volume":"5","author":"Bravo-Linares","year":"2019","journal-title":"J Glob Oncol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.rccan.2016.11.002","article-title":"Productividad cient\u00edfica de las l\u00edneas de investigaci\u00f3n y su contribuci\u00f3n para el control del c\u00e1ncer en Colombia","volume":"20","author":"Serrano","year":"2016","journal-title":"Rev Colomb Cancerol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"e9560","DOI":"10.1590\/1414-431x20199560","article-title":"The contribution of Latin American research to HPV epidemiology and natural history knowledge","volume":"53","author":"Sichero","year":"2020","journal-title":"Brazilian J Med Biol Res."},{"key":"B6","doi-asserted-by":"publisher","first-page":"S121","DOI":"10.1016\/j.canep.2016.07.015","article-title":"Cervical cancer in Central and South America: burden of disease and status of disease control","volume":"44","author":"Murillo","year":"2016","journal-title":"Cancer Epidemiol."},{"key":"B7","unstructured":"Seroprevalencia de SARS-Cov-2 durante la epidemia en Colombia: estudio pa\u00eds"},{"key":"B8","unstructured":"La ciencia en cifras"},{"key":"B9","unstructured":"Clinical Trials [Database]: January 2019 - June 2021"},{"key":"B10","unstructured":"Resoluci\u00f3n 730 de 2020: por la cual se establecen disposiciones para la aprobaci\u00f3n de los protocolos de investigaci\u00f3n cl\u00ednica con medicamentos, en el marco de la emergencia sanitria generada por el Covid-19"},{"key":"B11","unstructured":"Circular externa 1000-174-20. July 2020"},{"key":"B12","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/s40487-020-00124-2","article-title":"Cancer treatment and research during the COVID-19 pandemic: experience of the first 6 months","volume":"8","author":"de las Heras","year":"2020","journal-title":"Oncol Ther"},{"key":"B13","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1001\/jama.2020.9286","article-title":"Conducting clinical research during the COVID-19 pandemic: protecting scientific integrity","volume":"324","author":"Fleming","year":"2020","journal-title":"JAMA."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1935","DOI":"10.1001\/jama.2021.4609","article-title":"Remote research and clinical trial integrity during and after the coronavirus pandemic","volume":"325","author":"McDermott","year":"2021","journal-title":"JAMA."},{"year":"2018","key":"B15","article-title":"Boletin Trimestral De Las TIC, Julio de 2018"},{"key":"B16","doi-asserted-by":"publisher","first-page":"7311","DOI":"10.1245\/s10434-021-10406-2","article-title":"Impact of the COVID-19 pandemic on cancer clinical trials","volume":"28","author":"Boughey","year":"2021","journal-title":"Ann Surg Oncol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1407","DOI":"10.1007\/s11606-020-06455-0","article-title":"Team science, population health, and COVID-19: lessons learned adapting a population health research team to COVID-19","volume":"36","author":"Egede","year":"2021","journal-title":"J Gen Intern Med."},{"key":"B18","doi-asserted-by":"publisher","first-page":"102245","DOI":"10.1016\/j.ajp.2020.102245","article-title":"How COVID-19 may impact mental health research conduct, interpretation and priorities?","volume":"54","author":"Siddharth","year":"2020","journal-title":"Asian J Psychiatr"},{"key":"B19","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/j.ccell.2020.04.003","article-title":"Cancer research after COVID-19: where do we go from here?","volume":"37","author":"Colbert","year":"2020","journal-title":"Cancer Cell."},{"key":"B20","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1038\/s41568-021-00333-5","article-title":"Impact of COVID-19 on in vivo work and patient sample availability for cancer research","volume":"21","author":"Mulholland","year":"2021","journal-title":"Nat Rev Cancer."},{"key":"B21","doi-asserted-by":"publisher","first-page":"e2036353","DOI":"10.1001\/jamanetworkopen.2020.36353","article-title":"Trends in oncology clinical trials launched before and during the COVID-19 pandemic","volume":"4","author":"Lamont","year":"2021","journal-title":"JAMA Netw Open."},{"key":"B22","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1038\/d41573-021-00086-8","article-title":"COVID-19 impact on oncology clinical trials: a 1-year analysis","volume":"20","author":"Upadhaya","year":"2021","journal-title":"Nat Rev."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.3332\/ecancer.2021.1264","article-title":"Global cancer research in the era of COVID-19: a bibliometric analysis","volume":"15","author":"Van Hemelrijck","year":"2021","journal-title":"Ecancermedicalscience"},{"key":"B24","doi-asserted-by":"publisher","first-page":"102047","DOI":"10.1016\/j.ctrv.2020.102047","article-title":"Oncology clinical trials during the COVID-19 outbreak: lessons learnt during the crisis and future opportunities","volume":"88","author":"Fontana","year":"2020","journal-title":"Cancer Treat Rev"},{"key":"B25","doi-asserted-by":"publisher","first-page":"115","DOI":"10.4103\/picr.PICR_177_20","article-title":"Challenges and opportunities for sponsors in conducting clinical trials during a pandemic","volume":"11","author":"Davis","year":"2020","journal-title":"Perspect Clin Res."},{"key":"B26","unstructured":"2020"}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2021.750755\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T08:05:10Z","timestamp":1641283510000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2021.750755\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,4]]},"references-count":26,"alternative-id":["10.3389\/fpubh.2021.750755"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2021.750755","relation":{},"ISSN":["2296-2565"],"issn-type":[{"type":"electronic","value":"2296-2565"}],"subject":[],"published":{"date-parts":[[2022,1,4]]},"article-number":"750755"}}