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Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Ambient fine particulate matter (PM<jats:sub>2.5<\/jats:sub>) adversely affects human health and has been linked to a variety of skin disorders. However, little is known about the effects of PM<jats:sub>2.5<\/jats:sub> on psoriasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Beijing Medical Claim Data for Employees database recorded 500,266 outpatient visits for psoriasis during 2010\u20132017. A generalized additive quasi-Poisson model was used to examine the relationship between daily PM<jats:sub>2.5<\/jats:sub> concentrations and outpatient visits for psoriasis with stratification by sex, age, and season.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Short-term exposure to PM<jats:sub>2.5<\/jats:sub> was associated with outpatient visits for psoriasis-related health concerns. A same-day increase of 10 \u03bcg\/m<jats:sup>3<\/jats:sup> in PM<jats:sub>2.5<\/jats:sub> concentrations was associated with a 0.29% (95% confidence interval: 0.26\u20130.32%) increase in daily outpatient visits for psoriasis. Female and older patients appeared to be more sensitive to the effects of PM<jats:sub>2.5<\/jats:sub> (<jats:italic>P<\/jats:italic> &amp;lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Short-term elevations in PM<jats:sub>2.5<\/jats:sub> concentrations may be associated with exacerbations in psoriasis. Further work is warranted to confirm the findings and elucidate the underlying biological mechanisms.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2022.1015197","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T09:33:32Z","timestamp":1665567212000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":23,"title":["Short-term exposure to ambient fine particulate matter and psoriasis: A time-series analysis in Beijing, China"],"prefix":"10.3389","volume":"10","author":[{"given":"Junhui","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruotong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaomei","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonghua","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,10,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1945","DOI":"10.1001\/jama.2020.4006","article-title":"Pathophysiology, clinical presentation, and treatment of psoriasis. 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