{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T15:00:21Z","timestamp":1776870021744,"version":"3.51.2"},"reference-count":50,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T00:00:00Z","timestamp":1668643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Few studies have assessed trajectories of alcohol use in the general population, and even fewer studies have assessed the impact of brief intervention on the trajectories. Especially for low-risk drinkers, it is unclear what trajectories occur, whether they benefit from intervention, and if so, when and how long. The aims were first, to identify alcohol use trajectories among at-risk and among low-risk drinkers, second, to explore potential effects of brief alcohol intervention and, third, to identify predictors of trajectories.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adults aged 18-64 years were screened for alcohol use at a municipal registration office. Those with alcohol use in the past 12 months (<jats:italic>N<\/jats:italic> = 1646; participation rate: 67%) were randomized to assessment plus computer-generated individualized feedback letters or assessment only. Outcome was drinks\/week assessed at months 3, 6, 12, and 36. Alcohol risk group (at-risk\/low-risk) was determined using the Alcohol Use Disorders Identification Test\u2013Consumption. Latent class growth models were estimated to identify alcohol use trajectories among each alcohol risk group. Sex, age, school education, employment status, self-reported health, and smoking status were tested as predictors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For at-risk drinkers, a <jats:italic>light-stable<\/jats:italic> class (46%), a <jats:italic>medium-stable<\/jats:italic> class (46%), and a <jats:italic>high-decreasing<\/jats:italic> class (8%) emerged. The <jats:italic>light-stable<\/jats:italic> class tended to benefit from intervention after 3 years (Incidence Rate Ratio, IRR=1.96; 95% Confidence Interval, CI: 1.14\u20133.37). Male sex, higher age, more years of school, and current smoking decreased the probability of belonging to the <jats:italic>light-stable<\/jats:italic> class (<jats:italic>p<\/jats:italic>-values&amp;lt;0.05). For low-risk drinkers, a <jats:italic>very light-slightly increasing<\/jats:italic> class (72%) and a <jats:italic>light-increasin<\/jats:italic>g class (28%) emerged. The <jats:italic>very light-slightly increasing<\/jats:italic> class tended to benefit from intervention after 6 months (IRR=1.60; 95% CI: 1.12\u20132.28). Male sex and more years of school increased the probability of belonging to the <jats:italic>light-increasing<\/jats:italic> class (<jats:italic>p<\/jats:italic>-value &amp;lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most at-risk drinkers did not change, whereas the majority of low-risk drinkers increased alcohol use. There may be effects of alcohol feedback, with greater long-term benefits among persons with low drinking amounts. Our findings may help to identify refinements in the development of individualized interventions to reduce alcohol use.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2022.1027837","type":"journal-article","created":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T08:27:49Z","timestamp":1668673669000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Three-year trajectories of alcohol use among at-risk and among low-risk drinkers in a general population sample of adults: A latent class growth analysis of a brief intervention trial"],"prefix":"10.3389","volume":"10","author":[{"given":"Sophie","family":"Baumann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Staudt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennis","family":"Freyer-Adam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Zeiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gallus","family":"Bischof","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"John","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,11,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1954","DOI":"10.3390\/nu14091954","article-title":"Alcohol, drinking pattern, and chronic disease","volume":"14","author":"Barber\u00eda-Latasa","year":"2022","journal-title":"Nutrients."},{"key":"B2","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1016\/S2215-0366(18)30337-7","article-title":"The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"5","author":"Degenhardt","year":"2018","journal-title":"Lancet Psychiatry."},{"key":"B3","unstructured":"Rethinking drinking: Alcohol and your healthNIAAA2016"},{"key":"B4","doi-asserted-by":"publisher","first-page":"17","DOI":"10.7895\/IJADR.V5I2.222AIMS","article-title":"The alcohol use disorders identification test (AUDIT): a review of graded severity algorithms and national adaptations","volume":"5","author":"Babor","year":"2016","journal-title":"Int J Alc Drug Res."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1136\/bmj.319.7224.1523","article-title":"Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factors","volume":"319","author":"Rimm","year":"1999","journal-title":"Bmj."},{"key":"B6","doi-asserted-by":"publisher","first-page":"185","DOI":"10.15288\/jsad.2016.77.185","article-title":"Do \u201cModerate\u201d Drinkers Have Reduced Mortality Risk? A systematic review and meta-analysis of alcohol consumption and all-cause mortality","volume":"77","author":"Stockwell","year":"2016","journal-title":"J Stud Alcohol Drugs."},{"key":"B7","doi-asserted-by":"publisher","first-page":"e1003819","DOI":"10.1371\/journal.pmed.1003819","article-title":"Alcohol abstinence and mortality in a general population sample of adults in Germany: a cohort study","volume":"18","author":"John","year":"2021","journal-title":"PLoS Med."},{"key":"B8","doi-asserted-by":"publisher","first-page":"j2353","DOI":"10.1136\/bmj.j2353","article-title":"Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study","volume":"357","author":"Topiwala","year":"2017","journal-title":"BMJ."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1016\/S0140-6736(18)30134-X","article-title":"Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies","volume":"391","author":"Wood","year":"2018","journal-title":"Lancet."},{"key":"B10","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1016\/j.canep.2015.06.001","article-title":"European code against cancer 4th edition: 12 ways to reduce your cancer risk","volume":"39","author":"Schuz","year":"2015","journal-title":"Cancer Epidemiol."},{"key":"B11","unstructured":"Recommendations and public health and policy implications2018"},{"key":"B12","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.drugalcdep.2018.06.031","article-title":"Short-term stability of different drinking patterns over the course of four weeks among adults. A latent transition analysis","volume":"191","author":"Staudt","year":"2018","journal-title":"Drug Alcohol Depend."},{"key":"B13","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/S2215-0366(17)30130-X","article-title":"Change in non-abstinent WHO drinking risk levels and alcohol dependence: a 3 year follow-up study in the US general population","volume":"4","author":"Hasin","year":"2017","journal-title":"Lancet Psychiatry."},{"key":"B14","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1080\/14659891.2018.1497101","article-title":"Transitions to and from at-risk alcohol use in adults in the United States","volume":"24","author":"Saitz","year":"2019","journal-title":"J Subst Use."},{"key":"B15","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.drugalcdep.2014.11.020","article-title":"The impact of a stage tailored intervention on alcohol use trajectories among those who do not intend to change","volume":"147","author":"Baumann","year":"2015","journal-title":"Drug Alcohol Depend."},{"key":"B16","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1093\/biostatistics\/3.4.459","article-title":"General growth mixture modeling for randomized preventive interventions","volume":"3","author":"Muth\u00e9n","year":"2002","journal-title":"Biostatistics."},{"key":"B17","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.drugalcdep.2017.01.040","article-title":"Who benefits from computer-based brief alcohol intervention? Day-to-day drinking patterns as a moderator of intervention efficacy","volume":"175","author":"Baumann","year":"2017","journal-title":"Drug Alcohol Depend."},{"key":"B18","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1186\/s12889-018-5774-1","article-title":"Proactive expert system intervention to prevent or quit at-risk alcohol use (PRINT): study protocol of a randomized controlled trial","volume":"18","author":"Baumann","year":"2018","journal-title":"BMC Public Health."},{"key":"B19","doi-asserted-by":"publisher","first-page":"2056","DOI":"10.1111\/add.15412","article-title":"Effects of a brief alcohol intervention addressing the full spectrum of drinking in an adult general population sample: a randomized controlled trial","volume":"116","author":"Baumann","year":"2021","journal-title":"Addiction."},{"key":"B20","doi-asserted-by":"publisher","first-page":"e33345","DOI":"10.2196\/33345","article-title":"The moderating effect of educational background on the efficacy of a computer-based brief intervention addressing the full spectrum of alcohol use: randomized controlled trial","volume":"8","author":"Staudt","year":"2022","journal-title":"JMIR Pub Health Surveill."},{"key":"B21","first-page":"155","article-title":"The expert test and report on alcohol (EXTRA): development and evaluation of a computerized software program for problem drinkers","volume-title":"New Research on Alcoholism","author":"Bischof","year":"2007"},{"key":"B22","doi-asserted-by":"publisher","first-page":"38","DOI":"10.4278\/0890-1171-12.1.38","article-title":"The transtheoretical model of health behavior change","volume":"12","author":"Prochaska","year":"1997","journal-title":"Am J Health Promot."},{"key":"B23","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1037\/a0029368","article-title":"How well do TTM measures work among a sample of individuals with unhealthy alcohol use that is characterized by low readiness to change?","volume":"27","author":"Baumann","year":"2013","journal-title":"Psychol Addict Behav."},{"key":"B24","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1111\/j.1360-0443.1993.tb02093.x","article-title":"de la Fuente JR, Grant M. Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption\u2014II","volume":"88","author":"Saunders","year":"1993","journal-title":"Addiction."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1001\/archinte.158.16.1789","article-title":"The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking","volume":"158","author":"Bush","year":"1998","journal-title":"Arch Intern Med."},{"key":"B26","volume-title":"Mplus User's Guide. 8th Edn.","author":"Muth\u00e9n","year":"1998"},{"key":"B27","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/978-1-4612-1694-0_15","article-title":"Information Theory and an extension of the maximum likelihood principle","volume-title":"Selected Papers Hirotugu Akaike.","author":"Akaike","year":"1998"},{"key":"B28","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1214\/aos\/1176344136","article-title":"Estimating dimension of a model","volume":"6","author":"Schwarz","year":"1978","journal-title":"Ann Stat."},{"key":"B29","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/BF02294360","article-title":"Application of model-selection criteria to some problems in multivariate analysis","volume":"52","author":"Sclove","year":"1987","journal-title":"Psychometrika."},{"key":"B30","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1093\/biomet\/88.3.767","article-title":"Testing the number of components in a normal mixture","volume":"88","author":"Lo","year":"2001","journal-title":"Biometrika."},{"key":"B31","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1007\/BF01246098","article-title":"An entropy criterion for assessing the number of clusters in a mixture model","volume":"13","author":"Celeux","year":"1996","journal-title":"J Classif."},{"key":"B32","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1037\/1082-989X.4.2.139","article-title":"Analyzing developmental trajectories: A semiparametric, group-based approach","volume":"4","author":"Nagin","year":"1999","journal-title":"Psychol Methods."},{"key":"B33","doi-asserted-by":"publisher","first-page":"6774","DOI":"10.1080\/03610926.2015.1134575","article-title":"Relative effect sizes for measures of risk","volume":"46","author":"Olivier","year":"2017","journal-title":"Commun Stat Theor Methods."},{"key":"B34","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1093\/eurpub\/ckaa195","article-title":"Brief alcohol intervention at a municipal registry office: reach and retention","volume":"31","author":"Enders","year":"2021","journal-title":"Eur J Public Health."},{"key":"B35","first-page":"36","article-title":"Suchtstoffe, Suchtformen und ihre Auswirkungen: Alkohol","author":"John","year":"2019","journal-title":"DHS Jahrbuch Sucht"},{"key":"B36","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1081\/JA-120002803","article-title":"comparison of drinking patterns and alcohol-use-related problems in the United States and Germany, 1995","volume":"37","author":"Bloomfield","year":"2002","journal-title":"Subst Use Misuse."},{"key":"B37","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1177\/009145090202900306","article-title":"Attitudes toward alcohol policy in six EU countries","volume":"29","author":"Hemstr\u00f6m","year":"2002","journal-title":"Contemp Drug Probl."},{"key":"B38","doi-asserted-by":"publisher","first-page":"475","DOI":"10.15288\/jsa.2000.61.475","article-title":"Typologies of the cultural position of drinking","volume":"61","author":"Room","year":"2000","journal-title":"J Stud Alcohol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1111\/j.1530-0277.2009.00905.x","article-title":"Predicting treatment seekers' readiness to change their drinking behavior in the COMBINE study","volume":"33","author":"DiClemente","year":"2009","journal-title":"Alcohol Clin Exp Res."},{"key":"B40","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.drugalcdep.2013.11.017","article-title":"Regression to the mean and alcohol consumption: A cohort study exploring implications for the interpretation of change in control groups in brief intervention trials","volume":"135","author":"McCambridge","year":"2014","journal-title":"Drug Alcohol Depend."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1111\/acer.14340","article-title":"Stability of at-risk alcohol use screening in a general population sample","volume":"44","author":"Staudt","year":"2020","journal-title":"Alcohol Clin Exp Res."},{"key":"B42","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.jclinepi.2020.03.014","article-title":"Asking questions changes health-related behavior: an updated systematic review and meta-analysis","volume":"123","author":"Miles","year":"2020","journal-title":"J Clin Epidemiol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"e23748","DOI":"10.1371\/journal.pone.0023748","article-title":"Can simply answering research questions change behaviour? Systematic review and meta analyses of brief alcohol intervention trials","volume":"6","author":"McCambridge","year":"2011","journal-title":"PLoS ONE."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1111\/add.12677","article-title":"Does stage tailoring matter in brief alcohol interventions for job-seekers? A randomized controlled trial","volume":"109","author":"Freyer-Adam","year":"2014","journal-title":"Addiction."},{"key":"B45","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1037\/hea0000556","article-title":"In-person alcohol counseling versus computer-generated Feedback: results from a randomized controlled trial","volume":"37","author":"Freyer-Adam","year":"2018","journal-title":"Health Psychol."},{"key":"B46","doi-asserted-by":"publisher","first-page":"e0209442","DOI":"10.1371\/journal.pone.0209442","article-title":"Associations between socio-economic factors and alcohol consumption: a population survey of adults in England","volume":"14","author":"Beard","year":"2019","journal-title":"PLoS ONE."},{"key":"B47","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1111\/add.15261","article-title":"Latent alcohol use patterns and their link to depressive symptomatology in medical care patients","volume":"116","author":"Guertler","year":"2021","journal-title":"Addiction."},{"key":"B48","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.genhosppsych.2012.08.002","article-title":"Gender-specific predictors of risky alcohol use among general hospital inpatients","volume":"35","author":"Schnuerer","year":"2013","journal-title":"Gen Hosp Psychiatry."},{"key":"B49","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12916-015-0273-z","article-title":"Life course trajectories of alcohol consumption in the United Kingdom using longitudinal data from nine cohort studies","volume":"13","author":"Britton","year":"2015","journal-title":"BMC Med."},{"key":"B50","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1093\/eurpub\/ckp079","article-title":"Changes in alcohol consumption and drinking patterns during 11 years of follow-up among ageing men: the FinDrink study","volume":"20","author":"Ilomaki","year":"2010","journal-title":"Eur J Public Health."}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2022.1027837\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T08:27:55Z","timestamp":1668673675000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2022.1027837\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,17]]},"references-count":50,"alternative-id":["10.3389\/fpubh.2022.1027837"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2022.1027837","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,17]]},"article-number":"1027837"}}