{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:27:22Z","timestamp":1787027242732,"version":"build-2736575974"},"reference-count":68,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:00:00Z","timestamp":1670457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Medication adherence in HIV-infected pregnant women remains suboptimal. This systematic review and meta-analysis aimed to evaluate the effectiveness of interventions on improving antiretroviral adherence targeting among HIV-infected pregnant women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Five databases were screened to identify quasi-experimental studies and randomized controlled trials. The risk ratios (\n                      <jats:italic>RR)<\/jats:italic>\n                      and confidential intervals (\n                      <jats:italic>CI<\/jats:italic>\n                      ) were extracted to estimate the improvement in antiretroviral adherence after interventions compared with control conditions. This study was registered with PROSPERO, number CRD42021256317.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nine studies were included in the review, totaling 2,900 participants. Three interventions had significance: enhanced standard of care (eSOC, RR 1.14, 95%CI 1.07\u20131.22, Z = 3.79,\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.01), eSOC with supporter (RR 1.12, 95%CI 1.04\u20131.20, Z = 2.97,\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.01) and device reminder (RR 1.33, 95%CI 1.04\u20131.72, Z = 2.23,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.03).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The study supported the eSOC and the device reminder as effective intervention strategies for improving HIV medication adherence. Based on the current findings, the study called for more efforts to improve antiretroviral care for pregnant women through involving multicenter, large-sample, and high-quality research and combining the device reminder with other intervention methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Systematic review registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link>https:\/\/www.crd.york.ac.uk\/prospero\/display_record.php?ID=CRD42021256317<\/jats:ext-link>\n                      , identifier CRD42021256317.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2022.1056915","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T08:44:36Z","timestamp":1670489076000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Interventions to improve antiretroviral adherence in HIV-infected pregnant women: A systematic review and meta-analysis"],"prefix":"10.3389","volume":"10","author":[{"given":"Jie","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyi","family":"Yun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhan","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peige","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,12,8]]},"reference":[{"key":"B1","unstructured":""},{"key":"B2","unstructured":"Global AIDS Update"},{"key":"B3","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/s00737-019-00955-7","article-title":"The effect of male involvement and a prevention of mother-to-child transmission (PMTCT) intervention on depressive symptoms in perinatal HIV-infected rural South African women","volume":"23","author":"Peltzer","year":"2020","journal-title":"Arch Womens Ment Health."},{"key":"B4","doi-asserted-by":"publisher","first-page":"S240","DOI":"10.1097\/QAI.0000000000001370","article-title":"Building health system capacity through implementation research: experience of INSPIRE-a multi-country PMTCT implementation research project","volume":"75","author":"Newman","year":"2017","journal-title":"J Acquir Immune Defic Syndr."},{"key":"B5","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1111\/tmi.12881","article-title":"Uptake and performance of prevention of mother-to-child transmission and early infant diagnosis in pregnant HIV-infected women and their exposed infants at seven health centres in Addis Ababa, Ethiopia","volume":"22","author":"Girma","year":"2017","journal-title":"Trop Med Int Health."},{"key":"B6","doi-asserted-by":"publisher","first-page":"e123","DOI":"10.1097\/QAI.0000000000000760","article-title":"Implementation and operational research: integration of PMTCT and antenatal services improves combination antiretroviral therapy uptake for HIV-positive pregnant women in southern zambia: a prototype for option B+?","volume":"70","author":"Herlihy","year":"2015","journal-title":"J Acquir Immune Defic Syndr."},{"key":"B7","doi-asserted-by":"publisher","first-page":"17994","DOI":"10.7448\/IAS.16.1.17994","article-title":"Frequency and factors associated with adherence to and completion of combination antiretroviral therapy for prevention of mother to child transmission in western Kenya","volume":"16","author":"Ayuo","year":"2013","journal-title":"J Int AIDS Soc."},{"key":"B8","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1111\/j.1749-6632.2000.tb05498.x","article-title":"Antiretroviral pharmacology in pregnant women and their newborns","volume":"918","author":"Mirochnick","year":"2000","journal-title":"Ann N Y Acad Sci."},{"key":"B9","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1097\/00006250-200002000-00001","article-title":"Adherence to antiretroviral therapy by pregnant women infected with human immunodeficiency virus: a pharmacy claims-based analysis","volume":"95","author":"Laine","year":"2000","journal-title":"Obstet Gynecol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1093\/cid\/ciw500","article-title":"Adherence to antiretroviral therapy during and after pregnancy: cohort study on women receiving care in malawi's option B plus program","volume":"63","author":"Haas","year":"2016","journal-title":"Clin Infect Dis."},{"key":"B11","doi-asserted-by":"publisher","first-page":"2039","DOI":"10.1097\/QAD.0b013e328359590f","article-title":"Adherence to antiretroviral therapy during and after pregnancy in low-income, middle-income, and high-income countries: a systematic review and meta-analysis","volume":"26","author":"Nachega","year":"2012","journal-title":"Aids."},{"key":"B12","doi-asserted-by":"publisher","first-page":"E25","DOI":"10.1016\/j.ajic.2015.10.034","article-title":"Antiretroviral therapy among pregnant and postpartum women in China: a systematic review and meta-analysis","volume":"44","author":"Zhou","year":"2016","journal-title":"Am J Infect Control."},{"key":"B13","doi-asserted-by":"publisher","first-page":"958","DOI":"10.1080\/09540120701767208","article-title":"Adherence to antiretroviral treatment among pregnant and postpartum HIV-infected women","volume":"20","author":"Mellins","year":"2008","journal-title":"AIDS Care - Psychol Socio-Med Asp."},{"key":"B14","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1097\/QAI.0b013e31817bbe80","article-title":"Adherence to antiretrovirals among US women during and after pregnancy","volume":"48","author":"Bardeguez","year":"2008","journal-title":"JAIDS."},{"key":"B15","unstructured":"Compliance of antiviral treatment and its correlation with pregnant outcomes in pregnant women with HIV infection in Hangzhou1\n            Li.C\n            Yujuan.Z\n            Jiannv.H\n            Chengjing.T\n            Ying.ZS\n            Qiuquan.J\n          Chin J Clini Infect Dis2020"},{"key":"B16","doi-asserted-by":"publisher","first-page":"4154","DOI":"10.1007\/s10461-021-03283-z","article-title":"\u201cI found out I was pregnant, and I started feeling stressed\u201d: a longitudinal qualitative perspective of mental health experiences among perinatal women living with HIV","volume":"25","author":"Tuthill","year":"2021","journal-title":"AIDS Behav."},{"key":"B17","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1007\/s00737-018-0904-4","article-title":"The prevalence and determinants of depression among HIV-positive perinatal women receiving antiretroviral therapy in India","volume":"22","author":"Sarna","year":"2019","journal-title":"Arch Womens Mental Health."},{"key":"B18","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1186\/s12879-018-3087-8","article-title":"Factors affecting adherence to antiretroviral therapy among pregnant women in the Eastern Cape, South Africa","volume":"18","author":"Adeniyi","year":"2018","journal-title":"BMC Infect Dis"},{"key":"B19","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1007\/s10461-015-1209-5","article-title":"Psychosocial characteristics associated with both antiretroviral therapy adherence and risk behaviors in women living with HIV","volume":"20","author":"Holstad","year":"2016","journal-title":"AIDS Behav."},{"key":"B20","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1371\/journal.pone.0181730","article-title":"Demographic, clinical and behavioural determinants of HIV serostatus nondisclosure to sex partners among HIV-infected pregnant women in the Eastern Cape, South Africa","volume":"12","author":"Adeniyi","year":"2017","journal-title":"PLoS ONE"},{"key":"B21","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1371\/journal.pmed.1003650","article-title":"SMS messaging to improve retention and viral suppression in prevention of mother-to-child HIV transmission (PMTCT) programs in Kenya: a 3-arm randomized clinical trial","volume":"18","author":"Kinuthia","year":"2021","journal-title":"PLoS Med"},{"key":"B22","doi-asserted-by":"publisher","first-page":"S124","DOI":"10.1097\/QAI.0000000000001062","article-title":"Conditional cash transfers to increase retention in PMTCT care, antiretroviral adherence, and postpartum virological suppression: a randomized controlled trial","volume":"72","author":"Yotebieng","year":"2016","journal-title":"JAIDS."},{"key":"B23","doi-asserted-by":"publisher","first-page":"E125","DOI":"10.1097\/QAI.0b013e3182987ce6","article-title":"Noninferiority of a task-shifting HIV care and treatment model using peer counselors and nurses among ugandan women initiated on art: evidence from a randomized trial","volume":"63","author":"Kiweewa","year":"2013","journal-title":"JAIDS."},{"key":"B24","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1037\/a0028208","article-title":"Cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected injection drug users: a randomized controlled trial","volume":"80","author":"Safren","year":"2012","journal-title":"J Consult Clin Psychol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.ijid.2018.07.004","article-title":"meta-analysis of effectiveness of interventions to improve adherence in pregnant women receiving antiretroviral therapy in sub-Saharan Africa","volume":"74","author":"Omonaiye","year":"2018","journal-title":"Int J Infect Dis."},{"key":"B26","doi-asserted-by":"publisher","first-page":"3140","DOI":"10.1007\/s10461-019-02634-1","article-title":"VITAL start: video-based intervention to inspire treatment adherence for life-pilot of a novel video-based approach to HIV counseling for pregnant women living with HIV","volume":"23","author":"Kim","year":"2019","journal-title":"AIDS Behav."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1016\/S0149-2918(99)80026-5","article-title":"Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice","volume":"21","author":"Farmer","year":"1999","journal-title":"Clin Ther"},{"key":"B28","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s11904-020-00502-5","article-title":"Approaches to objectively measure antiretroviral medication adherence and drive adherence interventions","volume":"17","author":"Spinelli","year":"2020","journal-title":"Curr HIV\/AIDS Rep."},{"key":"B29","doi-asserted-by":"publisher","first-page":"687","DOI":"10.2147\/HIV.S261420","article-title":"Alarm Clock-Based reminder for improving low adherence on option B plus antiretroviral therapy among HIV positive pregnant and lactating mothers in Northern Ethiopia","volume":"12","author":"Gebretsadik","year":"2020","journal-title":"HIV AIDS-Res Palliative Care."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1080\/09540121.2017.1308464","article-title":"Role of male partner involvement in ART retention and adherence in Malawi's Option B plus program","volume":"29","author":"Wesevich","year":"2017","journal-title":"AIDS Care - Psychol Socio-Med Asp."},{"key":"B31","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1097\/00126334-200306010-00016","article-title":"Assessment of adherence to antiviral therapy in HIV-infected children using the Medication Event Monitoring System, pharmacy refill, provider assessment, caregiver self-report, and appointment keeping","volume":"33","author":"Farley","year":"2003","journal-title":"J Acquir Immune Defic Syndr."},{"key":"B32","unstructured":"90-90-90: An Ambitious Treatment Target To Help End The Aids Epidemic"},{"key":"B33","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.ijsu.2010.02.007","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"8","author":"Moher","year":"2010","journal-title":"Int J Surg."},{"key":"B34","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1056\/NEJMra050100","article-title":"Drug therapy - adherence to medication","volume":"353","author":"Osterberg","year":"2005","journal-title":"N Engl J Med."},{"key":"B35","doi-asserted-by":"publisher","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration's tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ (Clinical research ed)."},{"key":"B36","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.jclinepi.2010.04.026","article-title":"GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables","volume":"64","author":"Guyatt","year":"2011","journal-title":"J Clin Epidemiol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.jclinepi.2010.07.015","article-title":"GRADE guidelines: 3 rating the quality of evidence","volume":"64","author":"Balshem","year":"2011","journal-title":"J Clin Epidemiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jdent.2017.11.007","article-title":"In-office dental bleaching with light vs without light: a systematic review and meta-analysis","volume":"70","author":"Maran","year":"2018","journal-title":"J Dentistry."},{"key":"B39","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1136\/jech.52.6.377","article-title":"The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions","volume":"52","author":"Downs","year":"1998","journal-title":"J Clin Epidemiol."},{"key":"B40","unstructured":"Application of meta-regression and subgroup analyses of heterogeneity disposal in meta-analysis497501\n            ShiX-Q\n            WangZ-Z\n          18956686Zhonghua Liu Xing Bing Xue Za Zhi.292008"},{"key":"B41","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1371\/journal.pone.0181919","article-title":"Short-term effectiveness of a community health worker intervention for HIV-infected pregnant women in Tanzania to improve treatment adherence and retention in care: a cluster-randomized trial","volume":"12","author":"Nance","year":"2017","journal-title":"PLoS ONE"},{"key":"B42","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1177\/2325957413488203","article-title":"Improving PMTCT uptake in rural South Africa","volume":"13","author":"Weiss","year":"2014","journal-title":"J Int Assoc Provid AIDS Care."},{"key":"B43","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1097\/QAI.0b013e318262514f","article-title":"CD4, Viral load response, and adherence among antiretroviral-naive breast-feeding women receiving triple antiretroviral prophylaxis for prevention of mother-to-child transmission of HIV in Kisumu, Kenya","volume":"61","author":"Okonji","year":"2012","journal-title":"JAIDS."},{"key":"B44","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1080\/09540121.2010.516341","article-title":"Challenges in PMTCT antiretroviral adherence in northern KwaZulu-Natal, South Africa","volume":"23","author":"Mepham","year":"2011","journal-title":"AIDS Care - Psychol Socio-Med Asp."},{"key":"B45","doi-asserted-by":"publisher","first-page":"E85","DOI":"10.1097\/QAI.0b013e31821acc6e","article-title":"Improved detection of incident HIV infection and uptake of PMTCT services in labor and delivery in a high HIV prevalence setting","volume":"57","author":"Kieffer","year":"2011","journal-title":"JAIDS."},{"key":"B46","doi-asserted-by":"publisher","first-page":"148","DOI":"10.13419\/j.cnki.aids.2020.02.10","article-title":"Application of intelligent electronic medicine kits in medication compliance of HIV infected pregnant women with HAART","volume":"2","author":"Cheng","year":"2020","journal-title":"Chin J Aids & STD."},{"key":"B47","doi-asserted-by":"publisher","first-page":"E31","DOI":"10.1016\/S2352-3018(16)30206-5","article-title":"Interventions to improve adherence to antiretroviral therapy: a systematic review and network meta-analysis","volume":"4","author":"Kanters","year":"2017","journal-title":"Lancet Hiv."},{"key":"B48","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/s11904-019-00478-x","article-title":"Optimizing treatment for adults with HIV\/AIDS in China: successes over two decades and remaining challenges","volume":"17","author":"Cao","year":"2020","journal-title":"Curr HIV\/AIDS Rep."},{"key":"B49","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1097\/QAI.0000000000001026","article-title":"Attrition and opportunities along the HIV care continuum: findings from a population-based sample, North West Province, South Africa","volume":"73","author":"Lippman","year":"2016","journal-title":"J Acquir Immune Defic Syndr."},{"key":"B50","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1007\/s11764-017-0665-5","article-title":"Tai Chi and Qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis","volume":"12","author":"Wayne","year":"2018","journal-title":"J Can Survivorship."},{"key":"B51","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.clinthera.2005.02.010","article-title":"Impact of an adherence clinic on behavioral outcomes and virologic response in the treatment of HIV infection: a prospective, randomized, controlled pilot study","volume":"27","author":"Rathbun","year":"2005","journal-title":"Clin Ther."},{"key":"B52","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1093\/jpepsy\/jss132","article-title":"Motivational enhancement system for adherence (MESA): pilot randomized trial of a brief computer-delivered prevention intervention for youth initiating antiretroviral treatment","volume":"38","author":"Naar-King","year":"2013","journal-title":"J Pediatr Psychol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1080\/09540120701593489","article-title":"Using motivational interviewing to promote adherence to antiretroviral medications: a randomized controlled study","volume":"20","author":"DiIorio","year":"2008","journal-title":"AIDS Care - Psychol Socio-Med Asp."},{"key":"B54","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.13419\/j.cnki.aids.2020.11.12","article-title":"Social support status and its correlation with medication adherence in pregnant women with HIV\/AIDS","volume":"26","author":"Ying","year":"2020","journal-title":"Chin JAids & STD."},{"key":"B55","doi-asserted-by":"publisher","first-page":"775","DOI":"10.2147\/PPA.S61248","article-title":"The effect of medical device dose-memory functions on patients' adherence to treatment, confidence, and disease self-management","volume":"8","author":"Hall","year":"2014","journal-title":"Patient Prefer Adherence."},{"key":"B56","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1097\/QAI.0000000000000651","article-title":"Improving adherence to antiretroviral therapy with triggered real-time text message reminders: the china adherence through technology study","volume":"69","author":"Sabin","year":"2015","journal-title":"JAIDS."},{"key":"B57","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1002\/jia2.25198","article-title":"Internalized HIV stigma, ART initiation and HIV-1 RNA suppression in South Africa: exploring avoidant coping as a longitudinal mediator","volume":"21","author":"Earnshaw","year":"2018","journal-title":"J Int AIDS Soc"},{"key":"B58","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/s12911-015-0193-z","article-title":"Willingness to receive text message medication reminders among patients on antiretroviral treatment in North West Ethiopia: A cross-sectional study","volume":"15","author":"Kebede","year":"2015","journal-title":"BMC Medical Inform Decis Mak"},{"key":"B59","unstructured":"Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach 2016"},{"key":"B60","doi-asserted-by":"publisher","first-page":"1998","DOI":"10.1007\/s10461-018-2341-9","article-title":"A systematic review and meta-analysis of antiretroviral therapy (ART) adherence interventions for women living with HIV","volume":"23","author":"Pellowski","year":"2019","journal-title":"AIDS Behav."},{"key":"B61","unstructured":"Psychological experience of pregnant women infected with HIV- a qualitative study33614\n            LiuJ\n            XueY\n            GaoM\n            GuoL\n          24902487Chin J Modern Nurs.262014"},{"key":"B62","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1111\/hiv.12577","article-title":"National audit of perinatal HIV infections in the UK, 2006-2013: what lessons can be learnt?","volume":"19","author":"Peters","year":"2018","journal-title":"HIV Med."},{"key":"B63","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1046\/j.1365-2710.2001.00363.x","article-title":"Patient adherence to treatment: three decades of research. A comprehensive review","volume":"26","author":"Vermeire","year":"2001","journal-title":"J Clin Pharm Ther."},{"key":"B64","doi-asserted-by":"publisher","first-page":"2066","DOI":"10.1016\/j.clinthera.2004.12.018","article-title":"Adherence to a fixed-dose combination of rosiglitazone maleate\/metformin hydrochloride in subjects with type 2 diabetes mellitus: a retrospective database analysis","volume":"26","author":"Vanderpoel","year":"2004","journal-title":"Clin Ther."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1093\/jac\/dks011","article-title":"Use of dried blood spots for the determination of plasma concentrations of nevirapine and efavirenz","volume":"67","author":"Kromdijk","year":"2012","journal-title":"J Antimicrob Chemother."},{"key":"B66","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1002\/pds.1230","article-title":"Methods for evaluation of medication adherence and persistence using automated databases","volume":"15","author":"Andrade","year":"2006","journal-title":"Pharmacoepidemiol Drug Saf."},{"key":"B67","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1331\/JAPhA.2011.09154","article-title":"Selection of a validated scale for measuring medication adherence","volume":"51","author":"Lavsa","year":"2011","journal-title":"J Am Pharm Assoc."},{"key":"B68","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.brat.2018.02.004","article-title":"meta-analysis of dropout rates in acceptance and commitment therapy","volume":"104","author":"Ong","year":"2018","journal-title":"Behav Res Ther."}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2022.1056915\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T08:44:43Z","timestamp":1670489083000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2022.1056915\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,8]]},"references-count":68,"alternative-id":["10.3389\/fpubh.2022.1056915"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2022.1056915","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,8]]},"article-number":"1056915"}}