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The transmission of monkeypox occurs from infected animals to humans or through direct contact (sexual or skin-to-skin), respiratory droplets, and clothing such as towels. The incidence of monkeypox is rising drastically over the world. This short communication discusses the causes of the rising monkeypox cases and emphasizes strategies to prevent the spread of the virus.<\/jats:p>","DOI":"10.3389\/fpubh.2022.1082586","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T18:25:31Z","timestamp":1672943131000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Human monkeypox \u2014 After 40 years, an unintended consequence of smallpox eradication"],"prefix":"10.3389","volume":"10","author":[{"given":"Hussain Haider","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Khizer","family":"Molani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naqiha","family":"Shabbir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,1,5]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"198932","DOI":"10.1016\/j.virusres.2022.198932","article-title":"The virology of human monkeypox virus (hMPXV): A brief overview","volume":"322","author":"Lansiaux","year":"2022","journal-title":"Virus Res."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e26531","DOI":"10.7759\/cureus.26531","article-title":"Monkeypox: A comprehensive review of transmission, pathogenesis, and manifestation","volume":"14","author":"Kaler","year":"2022","journal-title":"Cureus."},{"key":"B3","doi-asserted-by":"publisher","first-page":"e0010141","DOI":"10.1371\/journal.pntd.0010141","article-title":"The changing epidemiology of human monkeypox-A potential threat? 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