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Four electronic databases were searched from December 1, 2019 to February 8, 2022 for relevant articles. Data synthesis, subgroup analysis, and sensitivity analysis were performed on the included studies. <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> and Q tests were applied to evaluate heterogeneity across studies. The risk of publication bias was assessed and visualized using a funnel plot. A total of 45 studies consisting of 2,655 patients with no symptoms at the screening point were included. Pooled results showed that in China, 65% of initial no-symptoms COVID-19 patients did not present any COVID-19-related symptom during follow-up or by end of disease course (asymptomatic infections). High proportions of initial no-symptoms COVID-19 patients (76%) and patients with asymptomatic infection (55%) had abnormal CT features at the screening point. High proportion of patients with asymptomatic infection had been detected Ig G<jats:sup>+<\/jats:sup> (72%) and\/or Ig M<jats:sup>+<\/jats:sup> (57%) at the screening point. The chest CT scan and SARS-CoV-2-specific antibody testing could serve as effective supplementary methods to identify asymptomatic cases in the early stage of SARS-CoV-2 infection. However, the chest CT scan and the SARS-CoV-2-specific IgM and IgG testing should not replace reverse transcription\u2013polymerase chain reaction (RT-PCR) for screening in asymptomatic patients. The combination of repeated RT-PCR, chest CT scans, and the SARS-CoV-2-specific IgM and IgG testing should be performed for those highly suspected SARS-CoV-2 infections.<\/jats:p><jats:sec><jats:title>Systematic Review Registration<\/jats:title><jats:p><jats:ext-link>https:\/\/www.crd.york.ac.uk\/PROSPERO\/#recordDetails<\/jats:ext-link>, identifier: CRD 42021261130.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2022.808471","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T05:08:50Z","timestamp":1648703330000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Epidemiological, Radiographical, and Laboratorial Characteristics of Chinese Asymptomatic Cases With COVID-19: A Systematic Review and Meta-Analysis"],"prefix":"10.3389","volume":"10","author":[{"given":"Haohao","family":"Yan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yudan","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenbin","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,3,31]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"E001","DOI":"10.3760\/cma.j.cn112137-20200205-00199","article-title":"Interpretation of \u201cGuidelines for the Diagnosis and Treatment of Novel Coronavirus (2019-nCoV) Infection by the National Health Commission (Trial Version 5)\u201d","volume":"100","author":"Lin","year":"2020","journal-title":"Zhonghua Yi Xue Za Zhi."},{"key":"B2","doi-asserted-by":"publisher","first-page":"101673","DOI":"10.1016\/j.tmaid.2020.101673","article-title":"Detection and analysis of nucleic acid in various biological samples of COVID-19 patients","volume":"37","author":"Wu","year":"2020","journal-title":"Travel Med Infect Dis."},{"key":"B3","doi-asserted-by":"publisher","first-page":"101668","DOI":"10.1016\/j.tmaid.2020.101668","article-title":"False negative rate of COVID-19 is eliminated by using nasal swab test","volume":"37","author":"Xie","year":"2020","journal-title":"Travel Med Infect Dis."},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-020-00822-x","article-title":"Covert coronavirus infections could be seeding new outbreaks","author":"Qiu","year":"2020","journal-title":"Nature."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1757","DOI":"10.1093\/infdis\/jiaa077","article-title":"A Familial Cluster of Infection Associated With the 2019 Novel Coronavirus Indicating Possible Person-to-Person Transmission During the Incubation Period","volume":"221","author":"Yu","year":"2020","journal-title":"J Infect Dis."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1056\/NEJMc2001573","article-title":"A Locally Transmitted Case of SARS-CoV-2 Infection in Taiwan","volume":"382","author":"Liu","year":"2020","journal-title":"N Engl J Med."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.1001\/jama.2020.2565","article-title":"Presumed Asymptomatic Carrier Transmission of COVID-19","volume":"323","author":"Bai","year":"2020","journal-title":"JAMA."},{"key":"B8","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1056\/NEJMc2001468","article-title":"Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany","volume":"382","author":"Rothe","year":"2020","journal-title":"N Engl J Med."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1056\/NEJMc2001737","article-title":"SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients","volume":"382","author":"Zou","year":"2020","journal-title":"N Engl J Med."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1101\/2020.03.18.20037994","article-title":"Investigating the Impact of Asymptomatic Carriers on COVID-19 Transmission","author":"Aguilar","year":"2020","journal-title":"medRxiv [Preprint]"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e0240205","DOI":"10.1371\/journal.pone.0240205","article-title":"What do we know about SARS-CoV-2 transmission? 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