{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:26:44Z","timestamp":1790908004244,"version":"4.1.0"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T00:00:00Z","timestamp":1647475200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:p>Patients treated in the intensive care unit (ICU) are closely monitored and receive intensive treatment. Such aggressive monitoring and treatment will generate high-granularity data from both electronic healthcare records and nursing charts. These data not only provide infrastructure for daily clinical practice but also can help to inform clinical studies. It is technically challenging to integrate and cleanse medical data from a variety of sources. Although there are several open-access critical care databases from western countries, there is a lack of this kind of database for Chinese adult patients. We established a critical care database involving patients with infection. A large proportion of these patients have sepsis and\/or septic shock. High-granularity data comprising laboratory findings, baseline characteristics, medications, international statistical classification of diseases (ICD) code, nursing charts, and follow-up results were integrated to generate a comprehensive database. The database can be utilized for a variety of clinical studies. The dataset is fully accessible at PhysioNet(<jats:ext-link>https:\/\/physionet.org\/content\/icu-infection-zigong-fourth\/1.0\/<\/jats:ext-link>).<\/jats:p>","DOI":"10.3389\/fpubh.2022.852410","type":"journal-article","created":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T08:56:48Z","timestamp":1647507408000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":25,"title":["Critical Care Database Comprising Patients With Infection"],"prefix":"10.3389","volume":"10","author":[{"given":"Ping","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanfang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rangui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuli","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,3,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1186\/s12879-021-06527-4","article-title":"Nosocomial sepsis and drug susceptibility pattern among patients admitted to adult intensive care unit of Ayder Comprehensive Specialized Hospital, Northern Ethiopia","volume":"21","author":"Dawit","year":"2021","journal-title":"BMC Infect Dis."},{"key":"B2","doi-asserted-by":"publisher","first-page":"8557","DOI":"10.21037\/apm-21-833","article-title":"Secondary infection in severe and critical COVID-19 patients in China: a multicenter retrospective study","volume":"10","author":"Sang","year":"2021","journal-title":"Ann Palliat Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1186\/s40560-020-00465-0","article-title":"Epidemiology of sepsis and septic shock in intensive care units between sepsis-2 and sepsis-3 populations: sepsis prognostication in intensive care unit and emergency room (SPICE-ICU)","volume":"8","author":"Abe","year":"2020","journal-title":"J Intensive Care."},{"key":"B4","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1136\/emermed-2018-208032","article-title":"Prolonged length of stay in the emergency department and increased risk of hospital mortality in patients with sepsis requiring ICU admission","volume":"36","author":"Zhang","year":"2019","journal-title":"Emerg Med J."},{"key":"B5","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.ejim.2011.06.016","article-title":"An observational study on bloodstream extended-spectrum beta-lactamase infection in critical care unit: incidence, risk factors and its impact on outcome","volume":"23","author":"Nasa","year":"2012","journal-title":"Eur J Intern Med."},{"key":"B6","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1111\/myc.12956","article-title":"Individual risk factors and critical care unit effects on Invasive Candida Infection occurring in critical care units in the UK: a multilevel model","volume":"62","author":"Patterson","year":"2019","journal-title":"Mycoses."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1007\/s00134-020-06106-2","article-title":"Epidemiology and burden of sepsis acquired in hospitals and intensive care units: a systematic review and meta-analysis","volume":"46","author":"Markwart","year":"2020","journal-title":"Intensive Care Med."},{"key":"B8","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The third international consensus definitions for sepsis and septic shock (sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA."},{"key":"B9","doi-asserted-by":"publisher","first-page":"ofy313","DOI":"10.1093\/ofid\/ofy313","article-title":"Sepsis in intensive care unit patients: worldwide data from the intensive care over nations audit","volume":"5","author":"Sakr","year":"2018","journal-title":"Open Forum Infect Dis"},{"key":"B10","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1513\/AnnalsATS.201411-498BC","article-title":"Trends in sepsis and infection sources in the United States. 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