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Public Health"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The Qinghai-Tibet Plateau is considered the most plague-heavy region in China, and skinning and eating marmots (<jats:italic>Marmota himalayana<\/jats:italic>) are understood to be the main exposure factors to plague. <jats:italic>Yersinia pestis<\/jats:italic> is relatively inactive during marmots' hibernation period. However, this case report shows plague infection risk is not reduced but rather increased during the marmot hibernation period if plague exposure is not brought under control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>The patient was a 45-year-old man who presented with high fever, swelling of axillary lymph nodes, and existing hand wounds on his right side. <jats:italic>Y. pestis<\/jats:italic> was isolated from his blood and lymphatic fluid. Hence, the patient was diagnosed with a confirmed case of bubonic plague. Later, his condition progressed to septicemic plague. Plague exposure through wounds and delays in appropriate treatment might have contributed to plague progression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case report reveals that excavating a hibernating marmot is a significant transmission route of plague. Plague prevention and control measures are priority needs during the marmot hibernation period.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2022.910872","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T05:09:00Z","timestamp":1653541740000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["First Case Report of Human Plague Caused by Excavation, Skinning, and Eating of a Hibernating Marmot (Marmota 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