{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:27:56Z","timestamp":1787027276079,"version":"build-2736575974"},"reference-count":172,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:00:00Z","timestamp":1677024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pesticides pose a risk for cancer development and progression. People are continuously exposed to such substances by several routes, including daily intake of contaminated food and water, especially in countries that are highly pesticide consumers and have very permissive legislation about pesticide contamination as Brazil. This work investigated the relationship among pesticides, food contamination, and dietary cancer risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Analyzed two social reports from the Brazilian Government: the Program for Analysis of Residues of Pesticides in Food (PARA) and The National Program for Control of Waste and Contaminants (PNCRC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results and discussion<\/jats:title>\n                    <jats:p>First, we characterized the main pesticide residues detected over the maximum limits allowed by legislation or those prohibited for use in food samples analyzed across the country. Based on this list, we estimated the dietary cancer risks for some of the selected pesticides. Finally, we searched for data about dietary cancer risks and carcinogenic mechanisms of each pesticide. We also provided a critical analysis concerning the pesticide scenario in Brazil, aiming to discuss the food contamination levels observed from a geographical, political, and public health perspective. Exposures to pesticides in Brazil violate a range of human rights when food and water for human consumption are contaminated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2023.1130893","type":"journal-article","created":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T04:18:46Z","timestamp":1677039526000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":21,"title":["Monitoring residues of pesticides in food in Brazil: A multiscale analysis of the main contaminants, dietary cancer risk estimative and mechanisms associated"],"prefix":"10.3389","volume":"11","author":[{"given":"Juliana Maria","family":"Bitencourt de Morais Valentim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiane Renata","family":"Fagundes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariane","family":"Okamoto Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e2mela","family":"Lonardoni Micheletti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geise Ellen","family":"Broto Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milena","family":"Cremer Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Geovana Leite Vacario","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana\u00edna Carla da","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thalita Basso","family":"Scandolara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaiane Carla","family":"Gaboardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano","family":"Zanetti Pessoa Candiotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Mara Serpeloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1bio","family":"Rodrigues Ferreira Seiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Panis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,2,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e0208546","DOI":"10.1371\/journal.pone.0208546","article-title":"Association of colorectal polyps and cancer with low-dose persistent organic pollutants: a case-control study","volume":"13","author":"Lee","year":"2018","journal-title":"PLoS ONE."},{"key":"B2","doi-asserted-by":"publisher","first-page":"584","DOI":"10.21577\/0100-4042.20170699","article-title":"A qu\u00edmica na avalia\u00e7\u00e3o do impacto \u00e0 sa\u00fade humana diante da exposi\u00e7\u00e3o aos pesticidas","volume":"44","author":"Medeiros","year":"2021","journal-title":"Qu"},{"key":"B3","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1590\/S1414-753X2004000200007","article-title":"Organoclorados: um problema de sa\u00fade p\u00fablica","author":"Flores","year":"2004","journal-title":"Artigos Ambient Soc."},{"key":"B4","doi-asserted-by":"publisher","first-page":"113972","DOI":"10.1016\/j.ecoenv.2022.113972","article-title":"Neurotoxicity of pesticides - a link to neurodegeneration","volume":"243","author":"Vellingiri","year":"2022","journal-title":"Ecotoxicol Environ Saf."},{"key":"B5","doi-asserted-by":"publisher","first-page":"194","DOI":"10.26444\/aaem\/121899","article-title":"Influence of pesticides on respiratory pathology \u2013 a literature review","volume":"27","author":"Tarmure","year":"2020","journal-title":"Ann Agric Environ Med"},{"key":"B6","doi-asserted-by":"publisher","first-page":"743","DOI":"10.3389\/fendo.2019.00743","article-title":"Pesticides with potential thyroid hormone-disrupting effects: A review of recent data","volume":"10","author":"Leemans","year":"2019","journal-title":"Front Endocrinol (Lausana)"},{"key":"B7","doi-asserted-by":"publisher","first-page":"6576","DOI":"10.3390\/ijerph18126576","article-title":"Reproductive health risks associated with occupational and environmental exposure to pesticides","volume":"18","author":"Fucic","year":"2021","journal-title":"Int J Environ Res Public Health."},{"key":"B8","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1001\/jamainternmed.2017.5092","article-title":"Pesticides and Human Reproduction","volume":"178","author":"Landrigan","year":"2018","journal-title":"JAMA Intern Med"},{"key":"B9","doi-asserted-by":"publisher","first-page":"17464","DOI":"10.1007\/s11356-021-17031-2","article-title":"Cancer and occupational exposure to pesticides: a bibliometric study of the past 10 years","volume":"29","author":"Pedroso","year":"2022","journal-title":"Environ Sci Pollut Res."},{"key":"B10","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/s12940-020-00670-2","article-title":"Environmental chemicals, breast cancer progression and drug resistance","volume":"19","author":"Koual","year":"2020","journal-title":"Environ Health."},{"key":"B11","unstructured":"2019"},{"key":"B12","unstructured":"2017"},{"key":"B13","unstructured":"2019"},{"key":"B14","doi-asserted-by":"publisher","first-page":"8072","DOI":"10.3390\/molecules27228072","article-title":"Pesticide residues in vegetables and fruits from farmer markets and associated dietary risks","volume":"27","author":"El-Sheikh","year":"2022","journal-title":"Molecules."},{"key":"B15","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1093\/aje\/kwac007","article-title":"Pesticide residue intake from fruit and vegetable consumption and risk of glioma","volume":"191","author":"Cote","year":"2022","journal-title":"Am J Epidemiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"112253","DOI":"10.1016\/j.envres.2021.112253","article-title":"Carcinogenic and non-carcinogenic risk assessment induced by pesticide residues in commercially available ready-to-eat raisins of Iran based on Monte Carlo Simulation","volume":"206","author":"Mahdavi","year":"2021","journal-title":"Environ Res."},{"key":"B17","doi-asserted-by":"publisher","first-page":"111780","DOI":"10.1016\/j.envres.2021.111780","article-title":"Assessment of toxicity and potential health risk from persistent pesticides and heavy metals along the Delhi stretch of river Yamuna","volume":"202","author":"Parween","year":"2021","journal-title":"Environ Res."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1093\/ije\/dyab015","article-title":"Prospective association between dietary pesticide exposure profiles and postmenopausal breast-cancer risk in the NutriNet-Sant\u00e9 cohort","volume":"50","author":"Rebouillat","year":"2021","journal-title":"Int J Epidemiol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"33133","DOI":"10.1007\/s11356-021-12747-7","article-title":"Human health risk assessment of dichlorodiphenyltrichloroethane (DDT) and hexachlorocyclohexane (HCH) pesticide residues in fruits and vegetables in Nigeria","volume":"28","author":"Odewale","year":"2021","journal-title":"Environ Sci Pollut Res Int"},{"key":"B20","unstructured":"2021"},{"key":"B21","unstructured":"2020"},{"key":"B22","unstructured":"2019"},{"key":"B23","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s10646-017-1874-4","article-title":"Exposure to a sublethal concentration of imidacloprid and the side effects on target and nontarget organs of Apis mellifera (Hymenoptera, Apidae)","volume":"27","author":"Catae","year":"2018","journal-title":"Ecotoxicology."},{"key":"B24","doi-asserted-by":"publisher","first-page":"e05178","DOI":"10.2903\/j.efsa.2018.5178","article-title":"Peer review of the pesticide risk assessment for bees for the active substance imidacloprid considering the uses as seed treatments and granules","volume":"16","year":"2018","journal-title":"EFSA J."},{"key":"B25","doi-asserted-by":"publisher","first-page":"160","DOI":"10.48075\/amb.v4i1.28294","article-title":"Res\u00edduos de agrot\u00f3xicos em alimentos no Brasil: considera\u00e7\u00f5es acerca do monitoramento do PARA (2001-2018): pesticides residues in food products in Brazil: Considerations about PARA monitoring (2001-2018)","volume":"4","author":"Gaboardi","year":"2022","journal-title":"Ambientes Rev Geogr Ecol Pol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.toxlet.2008.06.004","article-title":"Cumulative risk assessment of pesticide residues in food","volume":"180","author":"Boobis","year":"2008","journal-title":"Toxicol Lett."},{"key":"B27","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.nut.2018.04.018","article-title":"Associa\u00e7\u00f5es entre \u00edndice inflamat\u00f3rio diet\u00e9tico e incid\u00eancia de c\u00e2ncer de mama e pr\u00f3stata: uma revis\u00e3o sistem\u00e1tica e meta-an\u00e1lise","author":"Moradi","year":"2018","journal-title":"Nutri\u00e7\u00e3o."},{"key":"B28","doi-asserted-by":"publisher","first-page":"36","DOI":"10.11606\/s1518-8787.2021055002197","article-title":"Estimativa de ingest\u00e3o cr\u00f4nica de res\u00edduos de agrot\u00f3xicos por meio da dieta","volume":"55","year":"2021","journal-title":"Rev Sa\u00fade Publica"},{"key":"B29","doi-asserted-by":"publisher","first-page":"114025","DOI":"10.1016\/j.ijheh.2022.114025","article-title":"Prenatal ambient pesticide exposure and childhood retinoblastoma","volume":"245","author":"Thompson","year":"2022","journal-title":"Int J Hyg Environ Health"},{"key":"B30","doi-asserted-by":"publisher","first-page":"113881","DOI":"10.1016\/j.ijheh.2021.113881","article-title":"Proximity to endocrine-disrupting pesticides and risk of testicular germ cell tumors (TGCT) among adolescents: a population-based case-control study in california","volume":"239","author":"Swartz","year":"2022","journal-title":"Int J Hyg Environ Health."},{"key":"B31","doi-asserted-by":"publisher","first-page":"112703","DOI":"10.1016\/j.envres.2022.112703","article-title":"Exposure to neonicotinoid insecticides and their characteristic metabolites: association with human liver cancer","volume":"208","author":"Zhang","year":"2022","journal-title":"Environ Res"},{"key":"B32","doi-asserted-by":"publisher","first-page":"116848","DOI":"10.1016\/j.envpol.2021.116848","article-title":"Pilot study on the urinary excretion of the glyphosate metabolite aminomethyphosphonic acid and breast cancer risk: the multiethnic cohort study","volume":"277","author":"Franke","year":"2021","journal-title":"Environ Pollut."},{"key":"B33","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1590\/0103-1104201811714","article-title":"Agrot\u00f3xicos e seus impactos na sa\u00fade humana e ambiental: uma revis\u00e3o sistem\u00e1tica","volume":"42","author":"Lopes","year":"2018","journal-title":"Sa\u00fade em Debate."},{"key":"B34","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1093\/carcin\/bgr258","article-title":"Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk","volume":"33","author":"Barry","year":"2012","journal-title":"Carcinogenesis."},{"key":"B35","doi-asserted-by":"publisher","first-page":"112327","DOI":"10.1016\/j.ecoenv.2021.112327","article-title":"Association between pesticide exposure and colorectal cancer risk and incidence: a systematic review","volume":"219","author":"Matich","year":"2021","journal-title":"Ecotoxicol Environ Saf"},{"key":"B36","doi-asserted-by":"publisher","first-page":"429","DOI":"10.3233\/CBM-190636","article-title":"Genetic susceptibility of CYP1A1 gene and risk of pesticide exposure in prostate cancer","volume":"29","author":"Abhishek","year":"2020","journal-title":"Cancer Biomark."},{"key":"B37","doi-asserted-by":"publisher","first-page":"e070","DOI":"10.1097\/EE9.0000000000000070","article-title":"A case\u2013control study of breast cancer risk and ambient exposure to pesticides","volume":"3","author":"Tayour","year":"2019","journal-title":"Environ Epidemiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1781","DOI":"10.1093\/jnci\/djh324","article-title":"Cancer incidence among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study","volume":"96","author":"Lee","year":"2004","journal-title":"J Natl Cancer Inst."},{"key":"B39","doi-asserted-by":"publisher","first-page":"67011","DOI":"10.1289\/EHP6334","article-title":"Occupational Pesticide Use and Risk of Renal Cell Carcinoma in the Agricultural Health Study","volume":"128","author":"Andreotti","year":"2020","journal-title":"Environ Health Perspect"},{"key":"B40","doi-asserted-by":"publisher","first-page":"111078","DOI":"10.1016\/j.envres.2021.111078","article-title":"Residential proximity to pesticide application as a risk factor for childhood central nervous system tumors","volume":"197","author":"Lombardi","year":"2021","journal-title":"Environ Res."},{"key":"B41","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/s12940-020-00583-0","article-title":"Pesticide exposure and risk of aggressive prostate cancer among private pesticide applicators","volume":"19","author":"Pardo","year":"2020","journal-title":"Environ Health."},{"key":"B42","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1007\/s13193-022-01508-8","article-title":"an institution-based demographic study of urinary bladder cancer from North India","volume":"13","author":"Kumar","year":"2022","journal-title":"Indian J Surg Oncol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"113486","DOI":"10.1016\/j.ijheh.2020.113486","article-title":"Prenatal pesticide exposure and childhood leukemia- a california statewide case-control study","volume":"226","author":"Park","year":"2020","journal-title":"Int J Hyg Environ Health."},{"key":"B44","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1136\/oemed-2012-100845","article-title":"Lymphoma risk and occupational exposure to pesticides: results of the Epilymph study","volume":"70","author":"Cocco","year":"2013","journal-title":"Occup Environ Med."},{"key":"B45","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.mrrev.2019.02.001","article-title":"Exposure to glyphosate-based herbicides and risk for non-Hodgkin lymphoma: a meta-analysis and supporting evidence","volume":"781","author":"Zhang","year":"2019","journal-title":"Mutat Res Rev Mutat Res."},{"key":"B46","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1093\/jnci\/djx233","article-title":"Uso de glifosato e incid\u00eancia de c\u00e2ncer no estudo de sa\u00fade agr\u00edcola","volume":"110","author":"Andreotti","year":"2018","journal-title":"J Natl Cancer Inst."},{"key":"B47","doi-asserted-by":"publisher","first-page":"4449","DOI":"10.3390\/ijerph110404449","article-title":"Non-Hodgkin lymphoma and occupational exposure to agricultural pesticide chemical groups and active ingredients: a systematic review and meta-analysis","volume":"11","author":"Schinasi","year":"2014","journal-title":"Int J Environ Res Public Health"},{"key":"B48","doi-asserted-by":"publisher","first-page":"1010428317719782","DOI":"10.1177\/1010428317719782","article-title":"Changes in the expression of genes involved in cell cycle regulation and the relative telomere length in the process of canceration induced by omethoate","volume":"39","author":"Duan","year":"2017","journal-title":"Tumour Biol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1002\/jat.3638","article-title":"Low concentrations of permethrin and malathion induce numerical and structural abnormalities in KMT2A and IGH genes in vitro","volume":"38","author":"Navarrete-Meneses","year":"2018","journal-title":"J Appl Toxicol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"17003","DOI":"10.1289\/EHP6960","article-title":"Lifetime pesticide use and monoclonal gammopathy of undetermined significance in a prospective cohort of male farmers","volume":"129","author":"Hofmann","year":"2021","journal-title":"Environ Health Perspect."},{"key":"B51","doi-asserted-by":"publisher","first-page":"e109332","DOI":"10.1371\/journal.pone.0109332","article-title":"Non-hodgkin lymphoma risk and insecticide, fungicide and fumigant use in the agricultural health study","volume":"9","author":"Alavanja","year":"2014","journal-title":"PLoS ONE."},{"key":"B52","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1289\/ehp.1103942","article-title":"In utero pesticide exposure and leukemia in Brazilian children < 2 years of age","volume":"121","author":"Ferreira","year":"2012","journal-title":"Environ Health Perspect"},{"key":"B53","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1289\/ehp.1206432","article-title":"Lifetime pesticide use and telomere shortening among male pesticide applicators in the Agricultural Health Study","volume":"121","author":"Hou","year":"2013","journal-title":"Environ Health Perspect."},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2021.111501","article-title":"Residential exposure to carbamate, organophosphate, and pyrethroid insecticides in house dust and risk of childhood acute lymphoblastic leukemia","volume":"201","author":"Madrigal","year":"2021","journal-title":"Environ Res"},{"key":"B55","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1136\/oemed-2018-105559","article-title":"Longitudinal investigation of hematological alterations among permethrin-exposed pesticide applicators in the Biomarkers of Exposure and Effect in Agriculture study","volume":"76","author":"Shearer","year":"2019","journal-title":"Occup Environ Med."},{"key":"B56","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1002\/ijc.33740","article-title":"Occupational insecticide exposure and risk of non-hodgkin lymphoma: a pooled case-control study from the interlymph consortium","volume":"149","author":"De Roos","year":"2021","journal-title":"Int J Cancer."},{"key":"B57","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s12940-021-00696-0","article-title":"A tiered approach to prioritizing registered pesticides for potential cancer hazard evaluations: implications for decision making","volume":"20","author":"Schwingl","year":"2021","journal-title":"Environ Health"},{"key":"B58","doi-asserted-by":"publisher","first-page":"107568","DOI":"10.1016\/j.envint.2022.107568","article-title":"Neonicotinoid insecticides promote breast cancer progression via G protein-coupled estrogen receptor: in vivo, in vitro and in silico studies","volume":"170","author":"Li","year":"2022","journal-title":"Environ Int."},{"key":"B59","doi-asserted-by":"publisher","first-page":"77003","DOI":"10.1289\/EHP8608","article-title":"Application of an in vitro assay to identify chemicals that increase estradiol and progesterone synthesis and are potential breast cancer risk factors","volume":"129","author":"Cardona","year":"2021","journal-title":"Environ Health Perspect."},{"key":"B60","doi-asserted-by":"publisher","first-page":"331","DOI":"10.5487\/TR.2015.31.4.331","article-title":"Treatment of BG-1 ovarian cancer cells expressing estrogen receptors with lambda-cyhalothrin and cypermethrin caused a partial estrogenicity via an estrogen receptor-dependent pathway","volume":"31","author":"Kim","year":"2015","journal-title":"Toxicol Res."},{"key":"B61","doi-asserted-by":"publisher","first-page":"126426","DOI":"10.1016\/j.chemosphere.2020.126426","article-title":"Chlorpyrifos-induced cell proliferation in human breast cancer cell lines differentially mediated by estrogen and aryl hydrocarbon receptors and KIAA1363 enzyme after 24 h and 14 days exposure","volume":"251","author":"Moyano","year":"2020","journal-title":"Chemosphere."},{"key":"B62","doi-asserted-by":"publisher","first-page":"115093","DOI":"10.1016\/j.taap.2020.115093","article-title":"Angiogenesis signaling in breast cancer models is induced by hexachlorobenzene and chlorpyrifos, pesticide ligands of the aryl hydrocarbon receptor","volume":"401","author":"Z\u00e1rate","year":"2020","journal-title":"Toxicol Appl Pharmacol."},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2021.111989","article-title":"Endocrine disruptor chlorpyrifos promotes migration, invasion, and stemness phenotype in 3D cultures of breast cancer cells and induces a wide range of pathways involved in cancer progression","volume":"204","author":"Lasagna","year":"2022","journal-title":"Environ Res"},{"key":"B64","doi-asserted-by":"publisher","first-page":"e22640","DOI":"10.1002\/jbt.22640","article-title":"Organophosphate-pesticides induced survival mechanisms and APE1-mediated Nrf2 regulation in non-small-cell lung cancer cells","volume":"35","author":"Thakur","year":"2020","journal-title":"J Biochem Mol Toxicol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"114777","DOI":"10.1016\/j.taap.2019.114777","article-title":"Growth and neurite stimulating effects of the neonicotinoid pesticide clothianidin on human neuroblastoma SH-SY5Y cells","volume":"383","author":"Hirano","year":"2019","journal-title":"Toxicol Appl Pharmacol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.fct.2013.05.057","article-title":"Glyphosate induces human breast cancer cells growth via estrogen receptors","volume":"59","author":"Thongprakaisang","year":"2013","journal-title":"Food Chem Toxicol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"e0219610","DOI":"10.1371\/journal.pone.0219610","article-title":"Glyphosate-based herbicides at low doses affect canonical pathways in estrogen positive and negative breast cancer cell lines","volume":"14","author":"Stur","year":"2019","journal-title":"PLoS ONE."},{"key":"B68","doi-asserted-by":"publisher","first-page":"047014","DOI":"10.1289\/EHP2698","article-title":"Effects of neonicotinoid pesticides on promoter-specific aromatase (CYP19) expression in Hs578t breast cancer cells and the role of the VEGF pathway","volume":"126","author":"Caron-Beaudoin","year":"2018","journal-title":"Environ Health Perspect."},{"key":"B69","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1093\/toxsci\/kfab143","article-title":"Comparative toxicogenomics of glyphosate and roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in sprague-dawley rats","volume":"186","author":"Mesnage","year":"2022","journal-title":"Toxicol Sci."},{"key":"B70","doi-asserted-by":"publisher","first-page":"152298","DOI":"10.1016\/j.tox.2019.152298","article-title":"Omethoate induces pharyngeal cancer cell proliferation and G1\/S cell cycle progression by activation of Akt\/GSK-3\u03b2\/cyclin D1 signaling pathway","volume":"427","author":"Huo","year":"2019","journal-title":"Toxicology."},{"key":"B71","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.tiv.2017.06.013","article-title":"\u201cExposure to the insecticides permethrin and malathion induces leukemia and lymphoma-associated gene aberrations in vitro\u201d","volume":"44","author":"Navarrete-Meneses","year":"2017","journal-title":"Toxicol In Vitro."},{"key":"B72","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1093\/toxsci\/kfv220","article-title":"Effects of neonicotinoids on promoter-specific expression and activity of aromatase (CYP19) in human adrenocortical carcinoma (H295R) and primary umbilical vein endothelial (HUVEC) cells","volume":"149","author":"Caron-Beaudoin","year":"2022","journal-title":"Toxicol Sci"},{"key":"B73","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.taap.2017.07.018","article-title":"The use of a unique co-culture model of fetoplacental steroidogenesis as a screening tool for endocrine disruptors: the effects of neonicotinoids on aromatase activity and hormone production","volume":"332","author":"Caron-Beaudoin","year":"2017","journal-title":"Toxicol Appl Pharmacol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1016\/j.neuro.2022.06.002","article-title":"Neurotoxicity assessment of QoI strobilurin fungicides azoxystrobin and trifloxystrobin in human SH-SY5Y neuroblastoma cells: insights from lipidomics and mitochondrial bioenergetics","volume":"91","author":"Nguyen","year":"2022","journal-title":"Neurotoxicology."},{"key":"B75","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1080\/15376516.2020.1758981","article-title":"Triflumuron induces genotoxicity in both mice bone marrow cells and human Colon cancer cell line","volume":"30","author":"Timoumi","year":"2020","journal-title":"Toxicol Mech Methods."},{"key":"B76","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.chemosphere.2018.05.014","article-title":"Chitin synthesis inhibitors promote liver cancer cell metastasis via interfering with hypoxia-inducible factor 1\u03b1","volume":"206","author":"Ning","year":"2018","journal-title":"Chemosphere."},{"key":"B77","unstructured":"2006"},{"key":"B78","unstructured":""},{"key":"B79","unstructured":"2022"},{"key":"B80","doi-asserted-by":"publisher","first-page":"128619","DOI":"10.1016\/j.chemosphere.2020.128619","article-title":"Glyphosate and the key characteristics of an endocrine disruptor: a review","volume":"270","author":"Mu\u00f1oz","year":"2021","journal-title":"Chemosphere."},{"key":"B81","doi-asserted-by":"publisher","first-page":"652","DOI":"10.4067\/S0718-58392010000400017","article-title":"Glyphosate use in forest plantations","volume":"70","author":"Kogan","year":"2010","journal-title":"Chilean J Agric Res."},{"key":"B82","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1093\/carcin\/bgy105","article-title":"Glyphosate-based herbicides and cancer risk: a post-IARC decision review of potential mechanisms, policy and avenues of research","volume":"39","author":"Davoren","year":"2018","journal-title":"Carcinogenesis."},{"key":"B83","doi-asserted-by":"publisher","first-page":"627210","DOI":"10.3389\/fendo.2021.627210","article-title":"Controversies on endocrine and reproductive effects of glyphosate and glyphosate-based herbicides: a mini-review","volume":"12","author":"Ara\u00fajo-Ramosa","year":"2021","journal-title":"Front Endocrinol"},{"key":"B84","doi-asserted-by":"publisher","first-page":"671991","DOI":"10.3389\/fendo.2021.671991","article-title":"Epigenetic changes associated with exposure to glyphosate-based herbicides in mammales","volume":"12","author":"Rossetti","year":"2021","journal-title":"Front Endocrinol"},{"key":"B85","unstructured":"2022"},{"key":"B86","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1124\/jpet.108.143537","article-title":"Carbendazim inhibits cancer cell proliferation by suppressing microtubule dynamics","volume":"328","author":"Yenjerla","year":"2008","journal-title":"J Pharmacol Exp Ther."},{"key":"B87","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.yrtph.0.2014.05.016","article-title":"Reproductive and possible hormonal effects of carbendazim","volume":"69","author":"Rama","year":"2014","journal-title":"Regul Toxicol Pharmacol."},{"key":"B88","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.ntt.2011.08.014","article-title":"Neurobehavioral function and organophosphate insecticide use among pesticide applicators in the Agricultural Health Study","volume":"34","author":"Starks","year":"2012","journal-title":"Neurotoxicol Teratol."},{"key":"B89","unstructured":""},{"key":"B90","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.foodcont.2011.07.001","article-title":"Degradation of acephate and its metabolite methamidophos in rice during processing and storage","volume":"23","author":"Kong","year":"2012","journal-title":"Food Control."},{"key":"B91","unstructured":"ViennaR Foundation for Statistical Computing2021"},{"key":"B92","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1016\/j.joi.2017.08.007","article-title":"Bibliometrix: an R-tool for comprehensive science mapping analysis","volume":"11","author":"Aria","year":"2017","journal-title":"J Informetr."},{"key":"B93","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.ecoenv.2019.04.030","article-title":"Organochlorine and organophosphorous pesticides may induce colorectal cancer; a case-control study","volume":"178","author":"Abolhassani","year":"2019","journal-title":"Ecotoxicol Environ Saf."},{"key":"B94","doi-asserted-by":"publisher","first-page":"179","DOI":"10.5123\/S1679-49742007000400006","article-title":"Aedes aegypti: inseticidas, mecanismos de a\u00e7\u00e3o e resist\u00eancia","volume":"16","author":"Braga","year":"2007","journal-title":"Epidemiol Serv Sa\u00fade Bras"},{"key":"B95","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.cois.2018.09.009","article-title":"Neonicotinoids: molecular mechanisms of action, insights into resistance and impact on pollinators","volume":"30","author":"Ihara","year":"2018","journal-title":"Curr Opin Insect Sci."},{"key":"B96","doi-asserted-by":"publisher","first-page":"708","DOI":"10.3978\/j.issn.2223-4292.2015.06.01","article-title":"Mammalian models of chemically induced primary malignancies exploitable for imaging-based preclinical theragnostic research","volume":"5","author":"Liu","year":"2015","journal-title":"Quant Imaging Med Surg."},{"key":"B97","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1093\/carcin\/bgp252","article-title":"Basic properties and molecular mechanisms of exogenous chemical carcinogens","volume":"31","author":"Irigaray","year":"2010","journal-title":"Carcinogenesis."},{"key":"B98","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1191\/096032700701546442","article-title":"Epigenetic mechanisms of chemical carcinogenesis","author":"Klaunig","year":"2000","journal-title":"Hum Exp Toxicol."},{"key":"B99","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1590\/S0001-37652007000400004","article-title":"Chemical carcinogenesis","volume":"79","author":"Oliveira","year":"2007","journal-title":"Proc Braz Acad Sci."},{"key":"B100","doi-asserted-by":"publisher","first-page":"116280","DOI":"10.1016\/j.taap.2022.116280","article-title":"A systematic review of mechanistic studies on the relationship between pesticide exposure and cancer induction","volume":"456","author":"Ataei","year":"2022","journal-title":"Toxicol Appl Pharmacol."},{"key":"B101","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.envint.2017.05.018","article-title":"Residential exposure to pesticides as risk factor for childhood and young adult brain tumors: a systematic review and meta-analysis","volume":"106","author":"Van Maele-Fabry","year":"2017","journal-title":"Environ Int."},{"key":"B102","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1186\/s12885-020-07319-w","article-title":"Parental occupational exposure to pesticides and risk of childhood cancer in Switzerland: a census-based cohort study","volume":"20","author":"Coste","year":"2020","journal-title":"BMC Cancer."},{"key":"B103","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1515\/reveh-2020-0011","article-title":"Impact of pesticide exposure in childhood","volume":"35","author":"Pascale","year":"2020","journal-title":"Rev Environ Health."},{"key":"B104","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.biopha.2009.04.043","article-title":"Why pesticides could be a common cause of prostate and breast cancers in the French Caribbean Island, Martinique. An overview on key mechanisms of pesticide-induced cancer","volume":"63","author":"Landau-Ossondo","year":"2009","journal-title":"Biomed Pharmacother."},{"key":"B105","doi-asserted-by":"publisher","first-page":"282","DOI":"10.3892\/br.2016.575","article-title":"Occupational exposure and risk of breast cancer (review)","volume":"4","author":"Fenga","year":"2015","journal-title":"Biomedical Reports."},{"key":"B106","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.mrgentox.2018.12.004","article-title":"Early prediction of liver carcinogenicity due to occupational exposure to pesticides","volume":"838","author":"Saad-Hussein","year":"2018","journal-title":"Mut Res Genet Toxicol Environ Mutagen."},{"key":"B107","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.envpol.2017.08.028","article-title":"The association between non-Hodgkin lymphoma and organophosphate pesticides exposure: a meta-analysis","volume":"231","author":"Hu","year":"2017","journal-title":"Environ Pollut."},{"key":"B108","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1080\/10599240902773140","article-title":"Pesticides, chromosomal aberrations, and non-Hodgkin's lymphoma","volume":"14","author":"Chiu","year":"2009","journal-title":"Agromedicine."},{"key":"B109","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1289\/ehp.11318","article-title":"Cancer incidence among pesticide applicators exposed to permethrin in the Agricultural Health Study","author":"Rusiecki","year":"2009","journal-title":"Environ Health Perspect."},{"key":"B110","doi-asserted-by":"publisher","first-page":"461","DOI":"10.3390\/ijms17040461","article-title":"Linking pesticide exposure with pediatric leukemia: potential underlying mechanisms","volume":"17","author":"Hernandez","year":"2016","journal-title":"Int J Mol Sci."},{"key":"B111","doi-asserted-by":"publisher","first-page":"239","DOI":"10.7314\/APJCP.2015.16.1.239","article-title":"Relationship between exposure to pesticides and occurrence of acute leukemia in Iran","volume":"16","author":"Maryam","year":"2015","journal-title":"Asian Pac J Cancer Prev."},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0133382","article-title":"Pesticide use and relative leukocyte telomere length in the agricultural health study","volume":"10","author":"Andreotti","year":"2015","journal-title":"PLoS ONE."},{"key":"B113","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1093\/toxsci\/kfy039","article-title":"Cypermethrin promotes lung cancer metastasis via modulation of macrophage polarization by targeting microRNA-155\/Bcl6","volume":"163","author":"Huang","year":"2018","journal-title":"Toxicol Sci."},{"key":"B114","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1093\/toxsci\/kfs086","article-title":"The hepatocarcinogenic conazoles: cyproconazole, epoxiconazole, and propiconazole induce a common set of toxicological and transcriptional responses","volume":"127","author":"Hester","year":"2012","journal-title":"Toxicol Sci."},{"key":"B115","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.fct.2015.01.021","article-title":"Involvement of constitutive androstane receptor in liver hypertrophy and liver tumor development induced by triazole fungicides","volume":"78","author":"Tamura","year":"2015","journal-title":"Food Chem Toxicol."},{"key":"B116","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/s13045-019-0767-9","article-title":"Glyphosate induces benign monoclonal gammopathy and promotes multiple myeloma progression in mice","volume":"12","author":"Wang","year":"2019","journal-title":"J Hematol Oncol."},{"key":"B117","doi-asserted-by":"publisher","first-page":"443","DOI":"10.2131\/jts.43.443","article-title":"Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR","volume":"43","author":"Yoshimaru","year":"2018","journal-title":"J Toxicol Sci."},{"key":"B118","doi-asserted-by":"publisher","first-page":"153046","DOI":"10.1016\/j.tox.2021.153046","article-title":"Genomic comparisons between hepatocarcinogenic and non-hepatocarcinogenic organophosphate insecticides in the mouse liver","volume":"465","author":"Rooney","year":"2022","journal-title":"Toxicology."},{"key":"B119","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1177\/0192623318809304","article-title":"Reevaluation of hepatocellular neoplasms in CD-1 Mice from a 2-year oral carcinogenicity study with permethrin","volume":"47","author":"Quist","year":"2019","journal-title":"Toxicol Pathol."},{"key":"B120","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1016\/j.envpol.2019.07.081","article-title":"Mitochondrial dysfunction, apoptosis and transcriptomic alterations induced by four strobilurins in zebrafish (Danio rerio) early life stages","volume":"253","author":"Jiang","year":"2019","journal-title":"Environ Pollut."},{"key":"B121","doi-asserted-by":"publisher","first-page":"6414","DOI":"10.21203\/rs.3.rs-920465\/v2","article-title":"Resveratrol alleviates pyraclostrobin induced-lipidperoxidation, oxidative stress, and DNA damage in rats","volume":"3","author":"Navruz","year":"2022","journal-title":"Environ Sci Pollut Res."},{"key":"B122","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.canlet.2012.11.003","article-title":"Mini-review Integration of toxicological approaches with \u201c\u2018omic\u201d' and related technologies to elucidate mechanisms of carcinogenic action: propiconazole, an example","volume":"334","author":"Nesnow","year":"2013","journal-title":"Cancer Lett."},{"key":"B123","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.tox.2014.03.003","article-title":"Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action NIH Public Access","volume":"321","author":"Currie","year":"2014","journal-title":"Toxicology."},{"key":"B124","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.aquatox.2015.11.014","article-title":"Early life exposure to a rodent carcinogen propiconazole fungicide induces oxidative stress and hepatocarcinogenesis in medaka fish","volume":"170","author":"Tu","year":"2016","journal-title":"Aquatic Toxicol."},{"key":"B125","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1093\/toxsci\/kft182","article-title":"Concordance of transcriptional and apical benchmark dose levels for conazole-induced liver effects in mice","volume":"136","author":"Bhat","year":"2013","journal-title":"Toxicol Sci."},{"key":"B126","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1093\/mutage\/ges017","article-title":"Quantitative changes in endogenous DNA adducts correlate with conazole in vivo mutagenicity and tumorigenicity","volume":"27","author":"Roos","year":"2012","journal-title":"Mutagenesis."},{"key":"B127","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1621\/nrs.13002","article-title":"Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium","volume":"13","author":"Oshida","year":"2015","journal-title":"Nucl Recept Signal."},{"key":"B128","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.chemosphere.2017.08.108","article-title":"Potencial mutag\u00eanico, recombinog\u00eanico e carcinog\u00eanico do inseticida tiametoxam e produto formulado em c\u00e9lulas som\u00e1ticas de Drosophila melanogaster","volume":"187","author":"De Morais","year":"2017","journal-title":"Quimiosfera."},{"key":"B129","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.crimmu.2021.09.002","article-title":"Impact of the induction phase chemotherapy on cytokines and oxidative markers in peripheral and bone marrow plasma of children with acute lymphocytic leukemia","volume":"2","author":"Broto","year":"2021","journal-title":"Curr Res Immunol"},{"key":"B130","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1093\/carcin\/bgaa039","article-title":"NRF2 as a regulator of cell metabolism and inflammation in cancer","volume":"41","author":"He","year":"2020","journal-title":"Carcinogenesis."},{"key":"B131","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1177\/1091581813517906","article-title":"Glyphosate commercial formulation causes cytotoxicity, oxidative effects, and apoptosis on human cells: differences with its active ingredient","volume":"33","author":"Chaufan","year":"2014","journal-title":"Int J Toxicol."},{"key":"B132","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.envres.2020.109131","article-title":"Malathion induced cancer-linked gene expression in human lymphocytes","author":"Anjitha","year":"2020","journal-title":"Environ Res."},{"key":"B133","unstructured":"2022"},{"key":"B134","unstructured":"2022"},{"key":"B135","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1590\/0103-1104201711205","article-title":"Exposi\u00e7\u00e3o ambiental e ocupacional a agrot\u00f3xicos e o linfoma n\u00e3o Hodgkin","volume":"41","author":"Costa","year":"2017","journal-title":"Sa\u00fade em Debate."},{"key":"B136","first-page":"39","article-title":"Agrot\u00f3xicos, seus mitos e implica\u00e7\u00f5es","author":"Melgarejo","year":"2019","journal-title":"Sa\u00fade do Campo e Agrot\u00f3xicos: vulnerabilidades socioambientais, pol\u00edtico-institucionais e te\u00f3rico-metodol\u00f3gicas Recife: Ed UFPE. Ci\u00eanc. sa\u00fade coletiva"},{"key":"B137","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1590\/0103-11042022e220","article-title":"Toxicologia cr\u00edtica aplicada aos agrot\u00f3xicos \u2013 perspectivas em defesa da vida","volume":"46","author":"Friedrich","year":"2022","journal-title":"Sa\u00fade em Debate"},{"key":"B138","doi-asserted-by":"publisher","first-page":"358","DOI":"10.3390\/ijerph16030358","article-title":"Are our farm workers in danger? Genetic damage in farmers exposed to pesticides","volume":"16","author":"Marcelino","year":"2019","journal-title":"Int J Environ Res Public Health."},{"key":"B139","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.etap.2018.08.018","article-title":"Hazardous effects of chemical pesticides on human health-Cancer and other associated disorders","volume":"63","author":"Sabarwal","year":"2018","journal-title":"Environ Toxicol Pharmacol."},{"key":"B140","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1002\/ijc.32388","article-title":"Parental occupational exposure to pesticides, animals and organic dust and risk of childhood leukemia and central nervous system tumors: findings from the International Childhood Cancer Cohort Consortium (I4C)","volume":"146","author":"Patel","year":"2020","journal-title":"Int J Cancer."},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.1101\/2021.08.16.21259798","article-title":"Diagnostic evaluation of the presence of residues of glyphosate-AMPA and 2.4D pesticides in urine samples from people living in a rural Brazilian Community","author":"Candiotto","year":"2021","journal-title":"medRxiv."},{"key":"B142","doi-asserted-by":"publisher","first-page":"107321","DOI":"10.1016\/j.envint.2022.107321","article-title":"Widespread pesticide contamination of drinking water and impact on cancer risk in Brazil","volume":"165","author":"Panis","year":"2022","journal-title":"Environ Int."},{"key":"B143","article-title":"Decreto n\u00b0 4.074, de 4 de janeiro de 2002. Regulamenta a Lei n o 7.802, de 11 de julho de 1989, que disp\u00f5e sobre a pesquisa, a experimenta\u00e7\u00e3o, a produ\u00e7\u00e3o, a embalagem e rotulagem, o transporte, o armazenamento, a comercializa\u00e7\u00e3o, a propaganda comercial, a utiliza\u00e7\u00e3o, a importa\u00e7\u00e3o, a exporta\u00e7\u00e3o, o destino final dos res\u00edduos e embalagens, o registro, a classifica\u00e7\u00e3o, o controle, a inspe\u00e7\u00e3o e a fiscaliza\u00e7\u00e3o de agrot\u00f3xicos, seus componentes e afins, e d\u00e1 outras provid\u00eancias. Di\u00e1rio Oficial da Uni\u00e3o","year":"2002"},{"key":"B144","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1590\/1809-4422ASOC143673V1932016","article-title":"Constructing the politi - cal agenda of control over pesticides in Brazil","volume":"1","author":"Franco","year":"2016","journal-title":"Ambiente Sociedade."},{"key":"B145","unstructured":"2005"},{"key":"B146","unstructured":"CarneiroFF\n            AugustoLGS\n            RigottoRM\n            FriedrichK\n            B\u00fargioAC\n          Dossi\u00ea ABRASCO: um alerta sobre os impactos dos agrot\u00f3xicos na sa\u00fade. Rio de Janeiro: EPSJV"},{"key":"B147","doi-asserted-by":"publisher","first-page":"787438","DOI":"10.3389\/fpubh.2021.787438","article-title":"Evidence on human exposure to pesticides and the occurrence of health hazards in the Brazilian population: a systematic review","volume":"9","author":"Panis","year":"2022","journal-title":"Front Public Health."},{"key":"B148","unstructured":"1988"},{"key":"B149","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1590\/0102-311X00061820","article-title":"International regulatory situation of pesticides authorized for use in Brazil: potential for damage to health and environmental impacts","volume":"4","author":"Friedrich","year":"2021","journal-title":"Cad Sa\u00fade P\u00fablica S\u00e3o Paulo."},{"key":"B150","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1289\/ehp.6667","article-title":"Biomonitoramento de glifosato para agricultores e suas fam\u00edlias: resultados do estudo de exposi\u00e7\u00e3o familiar agr\u00edcola","volume":"112","author":"Acquavella","year":"2004","journal-title":"Perspect Sa\u00fade Ambiental."},{"key":"B151","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s12940-018-0435-5","article-title":"A evid\u00eancia da exposi\u00e7\u00e3o humana ao glifosato: uma revis\u00e3o","volume":"18","author":"Gillezeau","year":"2019","journal-title":"Sa\u00fade Ambiental"},{"key":"B152","doi-asserted-by":"publisher","first-page":"926434","DOI":"10.3389\/fenvs.2022.926434","article-title":"Permissiveness of Brazilian legislation, widespread contamination by pesticides in food and water, and risks to the population's Health","volume":"10","author":"Panis","year":"2022","journal-title":"Front Environ Sci"},{"key":"B153","unstructured":"2008"},{"key":"B154","volume-title":"Doubt is Their Product: How Industry's Assault on Science Threatens Your Health","author":"Michaels","year":"2008"},{"key":"B155","volume-title":"O uso de agrot\u00f3xicos no Sudoeste do Paran\u00e1 a partir de uma perspectiva geogr\u00e1fica multiescalar","author":"Gaboardi","year":"2021"},{"key":"B156","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1006\/rtph.1999.1371","article-title":"Safety evaluation and risk assessment of the herbicide Roundup and its active ingredient, glyphosate, for humans","volume":"31","author":"Williams","year":"2000","journal-title":"Regul Toxicol Pharmacol"},{"key":"B157","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1093\/annweh\/wxy104","article-title":"Avaliando as rotas de exposi\u00e7\u00e3o ao glifosato e sua contribui\u00e7\u00e3o para a carga corporal total: um estudo entre horticultores de amenidades","volume":"63","author":"Connolly","year":"2019","journal-title":"Ann Work Expo Sa\u00fade."},{"key":"B158","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1080\/1547691X.2020.1804492","article-title":"O impacto e a toxicidade do glifosato e de herbicidas \u00e0 base de glifosato na sa\u00fade e na imunidade","volume":"17","author":"Peillex","year":"2020","journal-title":"J Imunotoxicol."},{"key":"B159","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1289\/ehp.1409149","article-title":"IARC monographs: 40 years of evaluating carcinogenic hazards to humans","volume":"123","author":"Pearce","year":"2015","journal-title":"Environ Health Perspect."},{"key":"B160","unstructured":"2017"},{"key":"B161","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/S1470-2045(15)70134-8","article-title":"Carcinogenicity of tetrachlorvinphos, parathion, malathion, diazinon, and glyphosate","volume":"16","author":"Guyton","year":"2015","journal-title":"Lancet Oncol."},{"key":"B162","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2903\/j.efsa.2015.4302","article-title":"Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate","volume":"13","year":"2015","journal-title":"EFSA J."},{"key":"B163","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1080\/10408444.2016.1214681","article-title":"Glyphosate epidemiology expert panel review: a weight of evidence systematic review of the relationship between glyphosate exposure and non-Hodgkin's lymphoma or multiple myeloma","volume":"46","author":"Acquavella","year":"2016","journal-title":"Crit Rev Toxicol."},{"key":"B164","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1080\/10408444.2016.1214680","article-title":"Genotoxicity Expert Panel review: weight of evidence evaluation of the genotoxicity of glyphosate, glyphosate-based formulations, and aminomethylphosphonic acid","volume":"46","author":"Brusick","year":"2016","journal-title":"Crit Rev Toxicol."},{"key":"B165","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1080\/03601234.2016.1142748","article-title":"Systematic review and meta-analysis of glyphosate exposure and risk of lymphohematopoietic cancers","volume":"51","author":"Chang","year":"2016","journal-title":"J Environ Sci Health B."},{"key":"B166","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1080\/10408444.2016.1214678","article-title":"Glyphosate in the general population and in applicators: a critical review of studies on exposures","volume":"46","author":"Solomon","year":"2016","journal-title":"Crit Rev Toxicol."},{"key":"B167","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1080\/10408444.2016.1214677","article-title":"A review of the carcinogenic potential of glyphosate by four independent expert panels and comparison to the IARC assessment","volume":"46","author":"Williams","year":"2016","journal-title":"Crit Rev Toxicol."},{"key":"B168","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1080\/10408444.2016.1214679","article-title":"Glyphosate rodent carcinogenicity bioassay expert panel review","volume":"46","author":"Williams","year":"2016","journal-title":"Crit Rev Toxicol."},{"key":"B169","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1097\/CEJ.0000000000000289","article-title":"On the International Agency for Research on Cancer classification of glyphosate as a probable human carcinogen","volume":"27","author":"Tarone","year":"2018","journal-title":"Eur J Cancer Prev."},{"key":"B170","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1590\/S1415-47572007000300026","article-title":"Avalia\u00e7\u00e3o de dano ao DNA em uma popula\u00e7\u00e3o equatoriana exposta ao glifosato","volume":"30","author":"Paz-Y-Mi\u00f1o","year":"2007","journal-title":"Genet Mol Biol"},{"key":"B171","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1080\/15287390902929741","article-title":"Biomonitoramento do risco genot\u00f3xico em trabalhadores agr\u00edcolas de cinco regi\u00f5es colombianas: associa\u00e7\u00e3o \u00e0 exposi\u00e7\u00e3o ocupacional ao glifosato","volume":"72","author":"Bolognesi","year":"2009","journal-title":"J Toxicol Environ Health A."},{"key":"B172","unstructured":"2016"}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2023.1130893\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T04:19:11Z","timestamp":1677039551000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2023.1130893\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,22]]},"references-count":172,"alternative-id":["10.3389\/fpubh.2023.1130893"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2023.1130893","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,22]]},"article-number":"1130893"}}