{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:11:53Z","timestamp":1779883913533,"version":"3.53.1"},"reference-count":55,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:00:00Z","timestamp":1678320000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Previous epidemiological studies have shown that both long-term and short-term exposure to fine particulate matters (PM<jats:sub>2.5<\/jats:sub>) were associated with the morbidity and mortality of circulatory system diseases (CSD). However, the impact of PM<jats:sub>2.5<\/jats:sub> on CSD remains inconclusive. This study aimed to investigate the associations between PM<jats:sub>2.5<\/jats:sub> and circulatory system diseases in Ganzhou.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted this time series study to explore the association between ambient PM<jats:sub>2.5<\/jats:sub> exposure and daily hospital admissions for CSD from 2016 to 2020 in Ganzhou by using generalized additive models (GAMs). Stratified analyses were also performed by gender, age, and season.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Based on 201,799 hospitalized cases, significant and positive associations were found between short-term PM2.5 exposure and hospital admissions for CSD, including total CSD, hypertension, coronary heart disease (CHD), cerebrovascular disease (CEVD), heart failure (HF), and arrhythmia. Each 10 \u03bcg\/m<jats:sup>3<\/jats:sup> increase in PM<jats:sub>2.5<\/jats:sub> concentrations was associated with a 2.588% (95% confidence interval [CI], 1.161%\u20134.035%), 2.773% (95% CI, 1.246%\u20134.324%), 2.865% (95% CI, 0.786%\u20134.893%), 1.691% (95% CI, 0.239%\u20133.165%), 4.173% (95% CI, 1.988%\u20136.404%) and 1.496% (95% CI, 0.030%\u20132.983%) increment in hospitalizations for total CSD, hypertension, CHD, CEVD, HF, and arrhythmia, respectively. As PM<jats:sub>2.5<\/jats:sub> concentrations rise, the hospitalizations for arrhythmia showed a slow upward trend, while other CSD increased sharply at high PM<jats:sub>2.5<\/jats:sub> levels. In subgroup analyses, the impacts of PM<jats:sub>2.5<\/jats:sub> on hospitalizations for CSD were not materially changed, although the females had higher risks of hypertension, HF, and arrhythmia. The relationships between PM<jats:sub>2.5<\/jats:sub> exposure and hospitalizations for CSD were more significant among individuals aged \u226465 years, except for arrhythmia. PM<jats:sub>2.5<\/jats:sub> had stronger effects on total CSD, hypertension, CEVD, HF, and arrhythmia during cold seasons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PM<jats:sub>2.5<\/jats:sub> exposure was positively associated with daily hospital admissions for CSD, which might provide informative insight on adverse effects of PM<jats:sub>2.5<\/jats:sub>.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2023.1134516","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T06:52:47Z","timestamp":1678344767000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":19,"title":["Associations between short-term PM2.5 exposure and daily hospital admissions for circulatory system diseases in Ganzhou, China: A time series 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