{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T20:58:50Z","timestamp":1775509130180,"version":"3.50.1"},"reference-count":58,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T00:00:00Z","timestamp":1685059200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the otologic symptoms that present in patients with COVID-19 infection and investigate the pathogenic characteristics during the period of the pandemic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>This cross-sectional descriptive study included participants with COVID-19 infection. COVID-19 infection was verified in these patients by nucleic acid test or antigen test. An online questionnaire was developed to analyze the association between the COVID-19 pandemic and the characteristics of otologic symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 2,247 participants, of which nearly half had one or more otologic symptoms. The presents of otologic symptoms were associated with gender (OR = 1.575, <jats:italic>p<\/jats:italic> &amp;lt; 0.0001), age (OR = 0.972, <jats:italic>p<\/jats:italic> &amp;lt; 0.0001), and occupation (healthcare worker: <jats:italic>p<\/jats:italic> &amp;lt; 0.0001; personnel of enterprises or institutions: OR = 1.792, <jats:italic>p<\/jats:italic> &amp;lt; 0.0001; student: OR = 0.712, <jats:italic>p<\/jats:italic> &amp;lt; 0.044). The otologic symptoms following COVID-19 infection in order were vertigo (25.95%), tinnitus (19.05%), otalgia (19.00%), aural fullness (17.18%), hearing loss (11.62%), otorrhea (1.25%), and facial paralysis (0.27%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study shows that otologic symptoms are common among the COVID-19 infected participants and that these symptoms mostly recover spontaneously. During the corona-virus pandemic, the involvement of the cochleovestibular system and facial nerve should not be overlooked while treating the COVID-19 infected individuals.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2023.1184262","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T04:36:50Z","timestamp":1685075810000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["An online survey on clinical characteristics of otologic symptoms linked to COVID-19 infection"],"prefix":"10.3389","volume":"11","author":[{"given":"Linsui","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyi","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yufeng","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Pu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shixun","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,5,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.4102\/sajcd.v69i2.899","article-title":"Cochleovestibular findings linked to COVID-19: a scoping review for clinical care planning in South Africa","volume":"69","author":"Khoza-Shangase","year":"2022","journal-title":"S Afr J Commun Disord"},{"key":"B2","doi-asserted-by":"publisher","first-page":"3","DOI":"10.3233\/jad-200581","article-title":"Neurobiology of COVID-19","volume":"76","author":"Fotuhi","year":"2020","journal-title":"J Alzheimer's Dis JAD."},{"key":"B3","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1111\/joim.13089","article-title":"Clinical and epidemiological characteristics of 1420 European patients with mild-to-moderate coronavirus disease 2019","volume":"288","author":"Lechien","year":"2020","journal-title":"J Intern Med."},{"key":"B4","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1080\/14992027.2020.1798519","article-title":"Persistent self-reported changes in hearing and tinnitus in post-hospitalisation COVID-19 cases","volume":"59","author":"Munro","year":"2020","journal-title":"Int J Audiol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.1007\/s00405-021-06951-x","article-title":"COVID-19 caused hearing loss","volume":"279","author":"Dusan","year":"2022","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"956515","DOI":"10.3389\/fneur.2022.956515","article-title":"Vestibular disorders in patients after COVID-19 infection","volume":"13","author":"Pazdro-Zastawny","year":"2022","journal-title":"Front Neurol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"8808","DOI":"10.12998\/wjcc.v10.i25.8808","article-title":"Ear, nose, and throat manifestations of COVID-19 and its vaccines","volume":"10","author":"Al-Ani","year":"2022","journal-title":"World J Clin Cases."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1087896","DOI":"10.3389\/fneur.2022.1087896","article-title":"Editorial: neurotological consequences of long COVID","volume":"13","author":"Haider","year":"2022","journal-title":"Front Neurol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"707207","DOI":"10.3389\/fneur.2021.707207","article-title":"Auditory disturbances and SARS-CoV-2 infection: brain inflammation or cochlear affection? 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