{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:55:25Z","timestamp":1790794525608,"version":"4.1.0"},"reference-count":90,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T00:00:00Z","timestamp":1691020800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Air pollution may impair male fertility, but it remains controversial whether air pollution affects semen quality until now.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We undertake a meta-analysis to explore potential impacts of six pollutants exposure during the entire window (0\u201390\u2009days prior to ejaculation) and critical windows (0\u20139, 10\u201314, and 70\u201390\u2009days prior to ejaculation) on semen quality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seven databases were retrieved for original studies on the effects of six pollutants exposure for 90\u2009days prior to ejaculation on semen quality. The search process does not limit the language and search date. We only included original studies that reported regression coefficients (<jats:italic>\u03b2<\/jats:italic>) with 95% confidence intervals (CIs). The <jats:italic>\u03b2<\/jats:italic> and 95% CIs were pooled using the DerSimonian-Laird random effect models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PM<jats:sub>2.5<\/jats:sub> exposure was related with decreased total sperm number (10\u201314 lag days) and total motility (10\u201314, 70\u201390, and 0\u201390 lag days). PM<jats:sub>10<\/jats:sub> exposure was related with reduced total sperm number (70\u201390 and 0\u201390 lag days) and total motility (0\u201390 lag days). NO<jats:sub>2<\/jats:sub> exposure was related with reduced total sperm number (70\u201390 and 0\u201390 lag days). SO<jats:sub>2<\/jats:sub> exposure was related with declined total motility (0\u20139, 10\u201314, 0\u201390 lag days) and total sperm number (0\u201390 lag days).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Air pollution affects semen quality making it necessary to limit exposure to air pollution for Chinese men. When implementing protective measures, it is necessary to consider the key period of sperm development.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2023.1219340","type":"journal-article","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T23:11:58Z","timestamp":1691104318000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":18,"title":["Does air pollution exposure affect semen quality? Evidence from a systematic review and meta-analysis of 93,996 Chinese 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