{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T20:57:39Z","timestamp":1789765059116,"version":"4.0.1"},"reference-count":34,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T00:00:00Z","timestamp":1698364800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:p>This paper summarizes and analyzes the clinical data of a patient with Occupational hydrogen sulfide poisoning admitted to our hospital on March 4, 2023. On the morning of March 2, 2023, the patient worked at an environmental energy company (waste treatment plant) in Shandong Province for the first time, The job was to flush the sludge from the walls of the sludge treatment tank (anaerobic tank) with a water gun, which can release hydrogen sulfide gas. When the patient was about to start work after entering the tank for about 1\u2009min, he suddenly smelled a harsh and pungent odor, felt dizzy and weak, and then the patient suddenly fainted. After hearing the sound of the patient fainting, the workman waiting at the entrance of the tank immediately called someone to go into the tank and quickly pull the patient out, and sent to the local hospital. In the local hospital, the patient was confused, accompanied by irritability, convulsion and other manifestations, and was treated with sedation and nutritional support. Two days later, the patient\u2019s condition did not improve. For further diagnosis and treatment, the patient was transferred to the Department of Poisoning and Occupational Diseases in our hospital. After comprehensive treatment in our hospital, the patient got better and was discharged. Subsequent reexamination and follow-up showed that the patient recovered well. The work unit of the patient did not provide any personal protective equipment. According to the field investigation after the accident, the pipeline around the sludge treatment tank was blocked by sludge, resulting in a large amount of high concentration of H<jats:sub>2<\/jats:sub>S accumulated in the tank, causing the patient to faint soon after entering the tank, and his worker should be in the tank for a short time, and no health abnormalities were found. Hydrogen sulfide has a strong irritation to the human body, which can lead to asphyxia or even death in severe cases. The safety prevention and prevention knowledge of hydrogen sulfide poisoning should be popularized among enterprises and workers to reduce the occurrence of such incidents.<\/jats:p>","DOI":"10.3389\/fpubh.2023.1226282","type":"journal-article","created":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T11:53:55Z","timestamp":1698494035000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Case report: Analysis of a case of hydrogen sulfide poisoning in a waste treatment plant"],"prefix":"10.3389","volume":"11","author":[{"given":"Aerbusili","family":"Genjiafu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengdi","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangxing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangdong","family":"Jian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,10,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.f.Orsciint2010.09.008","article-title":"Toxicological analysis of 17 autopsy cases of hydrogen sulfide poisoning resulting from the inhalation of intentionally generated hydrogen sulfide gas","volume":"207","author":"Maebashi","year":"2011","journal-title":"Forensic Sci Int"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1146\/annurevpa.32.040192.000545","article-title":"Toxicology of hydrogen sulfide","volume":"32","author":"Reiffenstein","year":"1992","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"9638","DOI":"10.1038\/s41598-017-09960-1","article-title":"A rapid evaluation of acute hydrogen sulfide poisoning in blood based on DNA-cu\/ag nanocluster fluorescence probe","volume":"7","author":"Ding","year":"2017","journal-title":"Sci Rep"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2454","DOI":"10.1021\/ic2024082","article-title":"A retrievable and highly selective fluorescent probe for monitoring sulfide and imaging in living cells","volume":"51","author":"Zeng","year":"2012","journal-title":"Inorg Chem"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"9672","DOI":"10.1002\/anie.201104236","article-title":"A fluorescent probe for fast and quantitative detection of hydrogen sulfide in blood","volume":"50","author":"Peng","year":"2011","journal-title":"Angew Chem Int Ed Eng"},{"key":"ref6","first-page":"1277","article-title":"Hydrogen sulfide poisoning: review of 5 years' experience","volume":"117","author":"Burnett","year":"1977","journal-title":"Can Med Assoc J"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1097\/00043764-198505000-00018","article-title":"Health implication of occupational exposures to hydrogen sulfide","volume":"27","author":"Arnold","year":"1985","journal-title":"J Occup Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"e4","DOI":"10.1016\/j.forsciint.2019.04.026","article-title":"Toxicological investigations in a fatal and non-fatal accident due to hydrogen sulphide (H2S) poisoning","volume":"300","author":"Ventura Spagnolo","year":"2019","journal-title":"Forensic Sci Int"},{"key":"ref9","author":"Strickland","year":"2003"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"20831","DOI":"10.1038\/srep20831","article-title":"Hydrogen sulfide--mechanisms of toxicity and development of an antidote","volume":"6","author":"Jiang","year":"2016","journal-title":"Sci Rep"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"104474","DOI":"10.1016\/j.bd2019.05.013","article-title":"Hydrogen sulfide intoxication induced brain injury and methylene blue","volume":"133","author":"Haouzi","year":"2020","journal-title":"Neurobiol Dis"},{"key":"ref12","year":"2002"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1093\/occmed\/46.5.367","article-title":"Hydrogen sulphide","volume":"46","author":"Guidotti","year":"1996","journal-title":"Occup Med (Lond)"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/s0735-6757(99)90102-x","article-title":"Bronchial injury and pulmonary edema caused by hydrogen sulfide poisoning","volume":"17","author":"Tanaka","year":"1999","journal-title":"Am J Emerg Med"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/s0736-4679(00)00301-2","article-title":"Twenty-foot fall averts fatality from massive hydrogen sulfide exposure","volume":"20","author":"Gabbay","year":"2001","journal-title":"J Emerg Med"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/0735-6757(95)90094-2","article-title":"Occupational fatality and persistent neurological sequelae after mass exposure to hydrogen sulfide","volume":"13","author":"Snyder","year":"1995","journal-title":"Am J Emerg Med"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1007\/s004140050071","article-title":"The usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning: three cases","volume":"110","author":"Kage","year":"1997","journal-title":"Int J Legal Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.l.Egalmed2004.04.004","article-title":"Fatal hydrogen sulfide poisoning at a dye works","volume":"6","author":"Kage","year":"2004","journal-title":"Leg Med"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1097\/01.paf.0000163834.87968.08","article-title":"Death by sewer gas: case report of a double fatality and review of the literature","volume":"26","author":"Knight","year":"2005","journal-title":"Am J Forensic Med Pathol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1093\/jat\/15.3.148","article-title":"Determination of thiosulfate in body fluids by GC and GC\/MS","volume":"15","author":"Kage","year":"1991","journal-title":"J Anal Toxicol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1007\/BF01224772","article-title":"How to diagnose polysulphide poisoning from tissue samples","volume":"106","author":"Nagata","year":"1994","journal-title":"Int J Legal Med"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.l.Egalmed2007.11.005","article-title":"Two fatalities by hydrogen sulfide poisoning: variation of pathological and toxicological findings","volume":"10","author":"Ago","year":"2008","journal-title":"Leg Med"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s13181-019-00710-5","article-title":"Hydrogen sulfide toxicity: mechanism of action, clinical presentation, and countermeasure development","volume":"15","author":"Ng","year":"2019","journal-title":"J Med Toxicol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1093\/toxsci\/kfu140","article-title":"In vivo interactions between cobalt or ferric compounds and the pools of sulphide in the blood during and after H2S poisoning","volume":"141","author":"Haouzi","year":"2014","journal-title":"Toxicol Sci"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1111\/nyas.13015","article-title":"Developing effective countermeasures against acute hydrogen sulfide intoxication: challenges and limitations","volume":"1374","author":"Haouzi","year":"2016","journal-title":"Ann NY Acad Sci"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.tox.2004.05.020","article-title":"H2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial depolarisation","volume":"203","author":"Eghbal","year":"2004","journal-title":"Toxicology"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"209393","DOI":"10.1155\/2014\/209393","article-title":"The effects of acute hydrogen sulfide poisoning on cytochrome P450 isoforms activity in rats","volume":"2014","author":"Wang","year":"2014","journal-title":"Biomed Res Int"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s13181-017-0650-4","article-title":"Midazolam efficacy against acute hydrogen sulfide-induced mortality and neurotoxicity","volume":"14","author":"Anantharam","year":"2018","journal-title":"J Med Toxicol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/B978-0-444-62627-1.00008-1","article-title":"Hydrogen sulfide intoxication","volume":"131","author":"Guidotti","year":"2015","journal-title":"Handb Clin Neurol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1186\/s12883-022-02956-z","article-title":"Analysis of CT and MR imaging features of the brain in patients with hydrogen sulfide poisoning based on clinical symptom grading","volume":"22","author":"Tang","year":"2022","journal-title":"BMC Neurol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1097\/PAF.0000000000000055","article-title":"A fatal work-related poisoning by hydrogen sulfide: report on a case","volume":"34","author":"Lancia","year":"2013","journal-title":"Am J Forensic Med Pathol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"e01144","DOI":"10.1002\/rcr2.1144","article-title":"Fatal sequelae of hydrogen sulphide poisoning","volume":"11","author":"Goolam","year":"2023","journal-title":"Respirol Case Rep"},{"key":"ref33","first-page":"1097","article-title":"Hydrogen sulfide gas poisoning in fish garbage room: a report of a fisherman","volume":"67","author":"Sheikh","year":"2017","journal-title":"J Pak Med Assoc"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"292","DOI":"10.3760\/cma.j.cn121094-20210125-00045","article-title":"Analysis on incidence of occupational diseases in Guangzhou from 2010 to 2020","volume":"40","author":"Guo","year":"2022","journal-title":"Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi"}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2023.1226282\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T11:53:59Z","timestamp":1698494039000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2023.1226282\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,27]]},"references-count":34,"alternative-id":["10.3389\/fpubh.2023.1226282"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2023.1226282","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,27]]},"article-number":"1226282"}}