{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T20:10:54Z","timestamp":1788379854295,"version":"build-2803163510"},"reference-count":48,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The <jats:italic>Eidolon helvum<\/jats:italic> fruit bat is one of the most widely distributed fruit bats in Africa and known to be a reservoir for several pathogenic viruses that can cause disease in animals and humans. To assess the risk of zoonotic spillover, we conducted a serological survey of 304 serum samples from <jats:italic>E. helvum<\/jats:italic> bats that were captured for human consumption in Makurdi, Nigeria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using pseudotyped viruses, we screened 304 serum samples for neutralizing antibodies against viruses from the <jats:italic>Coronaviridae, Filoviridae, Orthomyxoviridae<\/jats:italic> and <jats:italic>Paramyxoviridae<\/jats:italic> families.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We report the presence of neutralizing antibodies against henipavirus lineage GH-M74a virus (odds ratio 6.23; <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001), Nipah virus (odds ratio 4.04; <jats:italic>p<\/jats:italic>\u2009=\u20090.00031), bat influenza H17N10 virus (odds ratio 7.25; <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001) and no significant association with Ebola virus (odds ratio 0.56; <jats:italic>p<\/jats:italic>\u2009=\u20090.375) in this bat cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The data suggest a potential risk of zoonotic spillover including the possible circulation of highly pathogenic viruses in <jats:italic>E. helvum<\/jats:italic> populations. These findings highlight the importance of maintaining sero-surveillance of <jats:italic>E. helvum,<\/jats:italic> and the necessity for further, more comprehensive investigations to monitor changes in virus prevalence, distribution over time, and across different geographic locations.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2023.1283113","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T06:32:41Z","timestamp":1701066761000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["Serological evidence of virus infection in Eidolon helvum fruit bats: implications for bushmeat consumption in Nigeria"],"prefix":"10.3389","volume":"11","author":[{"given":"Diego","family":"Cantoni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Mayora-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariliza","family":"Derveni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Del Rosario","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica O.","family":"Ameh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude 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