{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T22:31:46Z","timestamp":1771021906803,"version":"3.50.1"},"reference-count":44,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study investigated the prevalence of allergic diseases in Korean children aged 6 and below, focusing on the interplay between nutritional status, household income levels, and allergic disease occurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study used data from the 2019 Korea National Health and Nutrition Examination Survey, a nationwide comprehensive survey, and included a representative sample of 30,382 children under the age of 6 to investigate in detail the relationship between allergic diseases, nutritional intake, and socioeconomic factors. Logistic regression analysis was performed to identify factors associated with allergic diseases, including gender, BMI, eating habits, dietary supplement intake, and nutrient consumption. To predict childhood asthma, 14 machine learning models were compared using the \u2018pycaret\u2019 package in Python.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We discerned that 24.7% were diagnosed with allergic conditions like atopic dermatitis, asthma, and allergic rhinitis. Notably, household income exhibited a significant influence, with the lowest income quartile exhibiting higher prevalence rates of asthma, allergic rhinitis, and multiple allergic diseases. In contrast, the highest income quartile displayed lower rates of allergic rhinitis. Children diagnosed with allergic diseases demonstrated compromised intake of essential nutrients such as energy, dietary fiber, vitamin B1, sodium, potassium, and iron. Particularly noteworthy were the deficits in dietary fiber, vitamin A, niacin, and potassium intake among children aged 3\u20135 with allergies. Logistic regression analysis further elucidated that within low-income families, female children with higher BMIs, frequent dining out, dietary supplement usage, and altered consumption of vitamin B1 and iron faced an elevated risk of allergic disease diagnosis. Additionally, machine learning analysis pinpointed influential predictors for childhood asthma, encompassing BMI, household income, subjective health perception, height, and dietary habits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Our findings underscore the pronounced impact of income levels on the intricate nexus between allergic diseases and nutritional status. Furthermore, our machine learning insights illuminate the multifaceted determinants of childhood asthma, where physiological traits, socioeconomic circumstances, environmental factors, and dietary choices intertwine to shape disease prevalence. This study emphasizes the urgency of tailored nutritional interventions, particularly in socioeconomically disadvantaged populations, while also underscoring the necessity for comprehensive longitudinal investigations to unravel the intricate relationship between allergic diseases, nutritional factors, and socioeconomic strata.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2023.1287085","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T06:11:21Z","timestamp":1704694281000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Association between household income levels and nutritional intake of allergic children under 6\u2009years of age in Korea: 2019 Korea National Health and Nutrition Examination Survey and application of machine learning"],"prefix":"10.3389","volume":"11","author":[{"given":"Seungpil","family":"Jeong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yean Jung","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,1,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2481","DOI":"10.1016\/j.jaip.2019.04.013","article-title":"Association between allergic disease and developmental disorders in the National Health and nutrition examination survey","volume":"7","author":"Sohn","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"278","DOI":"10.3345\/cep.2019.01291","article-title":"Ten-year trends and prevalence of asthma, allergic rhinitis, and atopic dermatitis among the Korean population, 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Research Report1274KoreaMinistry of Health and Welfare2020"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"330","DOI":"10.4163\/jnh.2018.51.4.330","article-title":"Dietary status of young children in Korea based on the data of 2013~2015 Korea National Health and Nutrition Examination Survey","volume":"51","author":"Kim","year":"2018","journal-title":"J Nutr Health"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"3659","DOI":"10.1111\/all.15089","article-title":"Advances and highlights in biomarkers of allergic diseases","volume":"76","author":"Ogulur","year":"2021","journal-title":"Allergy"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1159\/000494931","article-title":"Recent advances in clinical allergy and immunology","volume":"177","author":"Simon","year":"2018","journal-title":"Int Arch Allergy Immunol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s40733-021-00077-x","article-title":"Treatment outcome clustering patterns correspond to discrete asthma phenotypes in children","volume":"7","author":"Bani\u0107","year":"2021","journal-title":"Asthma Res Pract"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"328","DOI":"10.3746\/jkfn.2018.47.3.328","article-title":"Analysis of consumption status of calcium with related factors in a Korean population: based on data from the 2013\u223c2015 Korean National Health and nutritional examination survey (KNHANES)","volume":"47","author":"Hur","year":"2018","journal-title":"J Korean Soc Food Sci Nutr"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"784","DOI":"10.3390\/nu9070784","article-title":"Can early omega-3 fatty acid exposure reduce risk of childhood allergic disease?","volume":"9","author":"Miles","year":"2017","journal-title":"Nutrients"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"e30","DOI":"10.3346\/jkms.2022.37.e30","article-title":"Clinical characteristics of atopic dermatitis in Korean school-aged children and adolescents according to onset age and severity","volume":"37","author":"Jeon","year":"2022","journal-title":"J Korean Med Sci"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"386","DOI":"10.2500\/aap.2008.29.3138","article-title":"Duration of breast-feeding and the risk of childhood allergic diseases in a developing country","volume":"29","author":"Ehlayel","year":"2008","journal-title":"Allergy Asthma Proc"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1186\/s12887-020-02158-x","article-title":"Late introduction of solids into infants\u2019 diets may increase the risk of food allergy development","volume":"20","author":"Hicke-Roberts","year":"2020","journal-title":"BMC Pediatr"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"492","DOI":"10.3390\/healthcare11040492","article-title":"Association between socioeconomic status and healthcare utilization for children with allergic diseases: Korean National Health and Nutritional Examination Survey (2015-2019)","volume":"11","author":"Kim","year":"2023","journal-title":"Healthcare"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"314","DOI":"10.4168\/aair.2017.9.4.314","article-title":"Allergic rhinitis in preschool children and the clinical utility of FeNO","volume":"9","author":"Yoon","year":"2017","journal-title":"Allergy Asthma Immunol Res"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1111\/j.1467-789X.2012.01055.x","article-title":"Gender difference of childhood overweight and obesity in predicting the risk of incident asthma: a systematic review and meta-analysis","volume":"14","author":"Chen","year":"2013","journal-title":"Obes Rev"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3200\/AEOH.61.1.5-10","article-title":"Respiratory health effects of air pollution gases: modification by education and income","volume":"61","author":"Cakmak","year":"2006","journal-title":"Arch Environ Occup Health"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"398","DOI":"10.3109\/02770903.2015.1126846","article-title":"Effects of poor asthma control, insomnia, anxiety and depression on quality of life in young asthmatics","volume":"53","author":"Sundbom","year":"2016","journal-title":"J Asthma"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1136\/thx.2010.134742","article-title":"Patterns of fetal and infant growth are related to atopy and wheezing disorders at age 3 years","volume":"65","author":"Pike","year":"2010","journal-title":"Thorax"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1136\/thoraxjnl-2012-202285","article-title":"Do fast foods cause asthma, rhinoconjunctivitis and eczema? 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