{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:00:47Z","timestamp":1779915647839,"version":"3.53.1"},"reference-count":16,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Alcohol consumption has been associated with the occurrence of many health conditions. We analyzed UK Biobank data to explore associations of various conditions to type and amount of alcohol consumed. UK Biobank is a large biomedical database providing information from UK participants, including lifestyle questionnaires and diagnosis data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using UK Biobank, we examined the relationship between weekly alcohol consumption, alcohol type and the incidence of eight select conditions. We calculated counts of individuals consuming each type diagnosed with these conditions. To assess the effect of alcohol consumption on each condition\u2019s prevalence, we used log-logistic regression models to generate dose\u2013response models for each alcohol type.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The alcohol consumed included: red wine (228,439 participants), white wine (188811), beer (182648), spirits (129418), and fortified wine (34598). We observed increased condition prevalence with increasing amounts of alcohol. This was especially seen for chronic obstructive lung disease, cirrhosis of liver, hypertension, gastritis, and type 2 diabetes. Beer consumers showed higher prevalence for most conditions while fortified wine had the largest increases in incidence rates. Only white wine showed decreased incidence for acute myocardial infarction. In general, the prevalence of many conditions was higher among alcohol consumers, particularly for hypertension, 33.8%, compared to 28.6% for non-drinkers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although many conditions were already prevalent among non-drinkers, participants consuming increasing amounts of alcohol had increased incidence rates for many of the studied conditions. This was especially true for consumers of beer and fortified wine, but also true to a lesser extent for consumers of spirits, red and white wine.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2024.1294492","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T04:48:43Z","timestamp":1716353323000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Alcohol consumption and its correlation with medical conditions: a UK Biobank study"],"prefix":"10.3389","volume":"12","author":[{"given":"Craig S.","family":"Mayer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Fontelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,5,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e236185","DOI":"10.1001\/jamanetworkopen.2023.6185","article-title":"Association between daily alcohol intake and risk of all-cause mortality: a systematic review and Meta-analyses","volume":"6","author":"Zhao","year":"2023","journal-title":"JAMA Netw Open"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1016\/j.jacep.2021.05.013","article-title":"Risk thresholds for Total and beverage-specific alcohol consumption and incident atrial fibrillation","volume":"7","author":"Tu","year":"2021","journal-title":"JACC"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"195","DOI":"10.4067\/S0716-97602004000200004","article-title":"Intake of beer, wine and spirits and risk of heavy drinking and alcoholic cirrhosis","volume":"37","author":"Gr\u00f8nb\u00e6k","year":"2004","journal-title":"Biol Res"},{"key":"ref4","first-page":"e204687","article-title":"Associations between medical conditions and alcohol consumption levels in an adult primary care population","volume-title":"JAMA Netw. Open.","author":"Sterling","year":"2020"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"4941","DOI":"10.3390\/ijerph19094941","article-title":"Risk of hypertension and type 2 diabetes in relation to changes in alcohol consumption: a Nationwide cohort study","volume":"19","author":"Choi","year":"2022","journal-title":"IJERPH"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.3390\/molecules23071684","article-title":"Contribution of red wine consumption to human health protection","volume":"23","author":"Snopek","year":"2018","journal-title":"Molecules"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"108","DOI":"10.3390\/nu12010108","article-title":"Benefits and risks of moderate alcohol consumption on cardiovascular disease: current findings and controversies","volume":"12","author":"Chiva-Blanch","year":"2019","journal-title":"Nutrients"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1017\/S0029665112000171","article-title":"Potential health benefits of moderate alcohol consumption: current perspectives in research","volume":"71","author":"Nova","year":"2012","journal-title":"Proc Nutr Soc"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e1001779","DOI":"10.1371\/journal.pmed.1001779","article-title":"UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age","volume":"12","author":"Sudlow","year":"2015","journal-title":"PLoS Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1002\/osp4.598","article-title":"Beer, wine, and spirits differentially influence body composition in older white adults\u2013a United Kingdom biobank study","volume":"8","author":"Larsen","year":"2022","journal-title":"Obes Sci Pract"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"e2019006","DOI":"10.4178\/epih.e2019006","article-title":"Dose-response meta-analysis: application and practice using the R software","volume":"41","author":"Shim","year":"2019","journal-title":"Epidemiol Health"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.tjem.2018.08.001","article-title":"User's guide to correlation coefficients","volume":"18","author":"Akoglu","year":"2018","journal-title":"Turk J Emerg Med"},{"key":"ref13","volume-title":"National Health Survey for England, 2021 part 2","year":"2023"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1097\/MCG.0000000000001192","article-title":"Gender differences among patients hospitalized with cirrhosis in the United States","volume":"54","author":"Rubin","year":"2020","journal-title":"J Clin Gastroenterol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/s11906-022-01183-8","article-title":"Sex differences in the prevalence, outcomes and Management of Hypertension","volume":"24","author":"Connelly","year":"2022","journal-title":"Curr Hypertens Rep"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"100132","DOI":"10.1016\/j.dadr.2023.100132","article-title":"Liquor consumption is associated with other medical conditions in females who consume alcohol","volume":"6","author":"Verplaetse","year":"2023","journal-title":"Drug Alcohol Depend Rep"}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2024.1294492\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T04:48:45Z","timestamp":1716353325000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2024.1294492\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,22]]},"references-count":16,"alternative-id":["10.3389\/fpubh.2024.1294492"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2024.1294492","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,22]]},"article-number":"1294492"}}