{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:18:34Z","timestamp":1780319914220,"version":"3.54.1"},"reference-count":50,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:00:00Z","timestamp":1715817600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The rise in e-cigarette use among youth is a significant global public health issue. It is important to identify those at increased risk and implement effective strategies to reduce e-cigarette popularity among the youth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aims to identify predictors of e-cigarette uptake in youths with no prior tobacco use, considering individual, familial and the broader societal environmental factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>For this investigation, a group of 2,487 tobacco-free youths was selected from 15 high schools in Shenzhen, China. Susceptibility to e-cigarettes was determined by assessing the possibility of future use and the openness to trying e-cigarettes if presented by friends. Both chi-square tests and logistic regression were applied to identify factors linked to susceptibility to e-cigarette use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the respondents, 5.5% (<jats:italic>n<\/jats:italic>\u2009=\u2009136) were found to be susceptible to e-cigarette use. The analysis revealed factors tied to this risk: perceptions of e-cigarettes, the impact of vaping peers, paternal parenting styles, the extent of social support, exposure to messages both for and against e-cigarettes use, and secondhand smoke (SHS) exposure. Youths who downplayed the addictive nature of e-cigarettes (aOR\u2009=\u20092.01; 95% CI: 1.14\u20133.55; <jats:italic>p<\/jats:italic>\u2009=\u20090.016), those with friends who engaged in vaping (aOR\u2009=\u20093.43\u20137.64; 95%CI: 2.36\u201320.42; <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001), those experiencing over-protective or rejective maternal parenting (aOR\u2009=\u20091.68\u20133.01; 95%CI: 1.11\u20135.77; <jats:italic>p<\/jats:italic>\u2009=\u20090.001\u20130.014) or rejective paternal parenting (aOR\u2009=\u20093.63; 95%CI: 1.99\u20136.59; <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001), those aware of e-cigarette advertisements (aOR\u2009=\u20091.82; 95%CI: 1.28\u20132.60; <jats:italic>p<\/jats:italic>\u2009=\u20090.001), and those exposed to SHS at home (aOR\u2009=\u20091.68; 95%CI: 1.17\u20132.41; <jats:italic>p<\/jats:italic>\u2009=\u20090.005) or at public places (aOR\u2009=\u20091.72\u20131.79; 95%CI: 1.21\u20132.57; <jats:italic>p<\/jats:italic>\u2009=\u20090.002\u20130.003) were more prone to e-cigarettes. In contrast, youths who believed using e-cigarettes reduces one\u2019s attractiveness (aOR\u2009=\u20090.34; 95%CI: 0.16\u20130.72; <jats:italic>p<\/jats:italic>\u2009=\u20090.005) or perceived that vaping made social interactions less enjoyable (aOR\u2009=\u20090.26; 95%CI: 0.12\u20130.58; <jats:italic>p<\/jats:italic>\u2009=\u20090.001), those who benefited from high social support (aOR\u2009=\u20090.30\u20130.60; 95%CI: 0.17\u20130.97; <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001), and those who noticed message about e-cigarettes\u2019 adverse consequence (aOR\u2009=\u20090.54; 95%CI: 0.38\u20130.77; <jats:italic>p<\/jats:italic>\u2009=\u20090.001) were less likely to be inclined toward e-cigarette use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The propensity of the youth to e-cigarette usage is shaped by a multiple element. An all-encompassing strategy that addresses the individual, familial, and the broader societal aspects is imperative for the effective prevention of e-cigarette initiation among youth.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2024.1320863","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T04:33:25Z","timestamp":1715834005000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Susceptibility to e-cigarette adoption among tobacco-na\u00efve youths: a cross-sectional study in Shenzhen, China"],"prefix":"10.3389","volume":"12","author":[{"given":"Ruilin","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanrou","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongzheng","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,5,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.15585\/mmwr.mm6745a5","article-title":"Notes 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