{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T13:12:36Z","timestamp":1782306756097,"version":"3.54.5"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T00:00:00Z","timestamp":1734307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Socially isolated individuals tend to have less access to cognitively stimulating activities, which could adversely impact their cognitive health. The Internet-Based Conversational Engagement Clinical Trial (I-CONECT) intervention was designed to deliver online conversation sessions to socially isolated older old adults to prevent cognitive decline. The current study examined the intervention efficacy on participants\u2019 weekly time spent out-of-home and their social interaction with family and friends.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The intervention group engaged in frequent conversations with trained interviewers via the Internet. Both intervention and control group participants received 10-min weekly phone check-in calls over 48\u202fweeks, during which they were asked to self-report their time (in hours) spent out of home and whether they had contacted family or friends during this week (yes\/no). Linear mixed-effect models for repeated measures were run for time spent out-of-home, and mixed-effect models with a logistic link for contact with family and friends. The intervention effect was modeled by including an interaction term of time (measured in weeks) and group assignments (intervention vs. control). We ran subgroup analyses for participants with normal cognition (NC) and mild cognitive impairment (MCI). All models controlled for age, sex, race, education, and the historical event of COVID-19.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>5,495 weekly records were included in the analysis. The main effect of time was statistically significant (<jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.001), suggesting participants spent more time out of home over time. Among the participants with NC, the intervention group had a steeper increase in their time spent out-of-home (<jats:italic>p<\/jats:italic>\u202f=\u202f0.016) compared with the control group. Among the participants with MCI, the intervention group had an increased likelihood of contacting friends over time (<jats:italic>p<\/jats:italic>\u202f=\u202f0.001) than the control group. The intervention effect on contact with family was not significant for either the NC or MCI group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The I-CONECT intervention enhanced social activities among socially isolated older old participants, which could provide additional cognitive stimulation and prevent cognitive decline.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2024.1429331","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T06:19:30Z","timestamp":1734329970000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["I-CONECT intervention effects on weekly time spent outside of home and social contacts among socially isolated older adults"],"prefix":"10.3389","volume":"12","author":[{"given":"Kexin","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao-Yi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa C.","family":"Silbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A.","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko H.","family":"Dodge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.tics.2009.06.005","article-title":"Perceived social isolation and cognition","volume":"13","author":"Cacioppo","year":"2009","journal-title":"Trends Cogn Sci"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3389\/fnagi.2022.896218","article-title":"Feelings of loneliness and isolation: social brain and social cognition in the elderly and Alzheimer\u2019s disease","volume":"14","author":"Morese","year":"2022","journal-title":"Front Aging Neurosci"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1017\/S1041610221000776","article-title":"Effects of restriction of activities and social isolation on risk of dementia in the community","volume":"33","author":"Goldberg","year":"2021","journal-title":"Int Psychogeriatr"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1017\/S1041610221001113","article-title":"Restriction of activities, social isolation, and dementia","volume":"33","author":"Sachdev","year":"2021","journal-title":"Int Psychogeriatr"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/S0140-6736(20)30367-6","article-title":"Dementia prevention, intervention, and care: 2020 report of the lancet commission","volume":"396","author":"Livingston","year":"2020","journal-title":"Lancet"},{"key":"ref6","volume-title":"Addressing the impact of COVID-19 on social isolation and loneliness","author":"Berg-Weger","year":"2024"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1177\/0956797613499592","article-title":"The impact of sustained engagement on cognitive function in older adults: the synapse project","volume":"25","author":"Park","year":"2014","journal-title":"Psychol Sci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"66","DOI":"10.3389\/fncel.2019.00066","article-title":"The impact of studying brain plasticity","volume":"13","author":"Mateos-Aparicio","year":"2019","journal-title":"Front Cell Neurosci"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"2417","DOI":"10.1007\/s11064-020-03102-2","article-title":"Enriched environment and social isolation affect cognition ability via altering excitatory and inhibitory synaptic density in mice Hippocampus","volume":"45","author":"Wang","year":"2020","journal-title":"Neurochem Res"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"gnad147","DOI":"10.1093\/geront\/gnad147","article-title":"Internet-based conversational engagement randomized controlled clinical trial (I-CONECT) among socially isolated adults 75+ years old with normal cognition or MCI: topline results","volume":"64","author":"Dodge","year":"2023","journal-title":"The Gerontologist"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"714813","DOI":"10.3389\/fdgth.2021.714813","article-title":"The internet-based conversational engagement clinical trial (I-CONECT) in socially isolated adults 75+ years old: randomized controlled trial protocol and COVID-19 related study modifications","volume":"3","author":"Yu","year":"2021","journal-title":"Front Digit Health"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.cpr.2010.04.001","article-title":"What is behavioral activation? 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