{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T04:12:27Z","timestamp":1788754347453,"version":"build-2803163510"},"reference-count":49,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T00:00:00Z","timestamp":1727827200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>This study aimed to examine the knowledge, attitude, and practice (KAP) of women in Beijing regarding cervical precancerous lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This web-based, cross-sectional study included women at Dongzhimen Hospital of Beijing University of Chinese Medicine between March 13, 2024 and April 9, 2024. A self-administered questionnaire was developed to collect participants\u2019 demographic information and KAP scores toward cervical precancerous lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 951 valid questionnaires, with a mean age of 40.0\u2009years. The mean knowledge, attitude, and practice scores were 12.55\u2009\u00b1\u20096.23 (possible range: 0\u201326), 50.66\u2009\u00b1\u20097.48 (possible range: 13\u201365), and 26.13\u2009\u00b1\u20094.98 (possible range: 7\u201335), respectively. The knowledge score (OR\u2009=\u20091.071, 95%CI: 1.040\u20131.103, <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001), currently married (OR\u2009=\u20090.548, 95%CI: 0.304\u20130.985, <jats:italic>p<\/jats:italic>\u2009=\u20090.045), and with a history of HPV infection (OR\u2009=\u20092.302, 95%CI: 1.062\u20134.990, <jats:italic>p<\/jats:italic>\u2009=\u20090.035) were independently associated with the attitude score. The knowledge score (OR\u2009=\u20091.155, 95%CI: 1.119\u20131.192, <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001), monthly income &amp;gt;20,000 (OR\u2009=\u20092.793, 95%CI: 1.249\u20136.248, <jats:italic>p<\/jats:italic>\u2009=\u20090.012), a history of HPV infection (OR\u2009=\u20090.380, 95%CI: 0.222\u20130.650, <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001), unknown HPV infection status (OR\u2009=\u20090.289, OR\u2009=\u20090.177\u20130.473, p\u2009&amp;lt;\u20090.001), vaccinated against HPV (OR\u2009=\u20091.752, 95%CI: 1.221\u20132.514, <jats:italic>p<\/jats:italic>\u2009=\u20090.002), giving birth to one child (OR\u2009=\u20091.991, 95%CI: 1.186\u20133.341, <jats:italic>p<\/jats:italic>\u2009=\u20090.009), and giving birth to two or more children (OR\u2009=\u20092.160, 95%CI: 1.240\u20133.763, <jats:italic>p<\/jats:italic>\u2009=\u20090.007) were independently associated with the practice score. The structured equation model showed that knowledge directly influenced attitude (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.237, <jats:italic>p<\/jats:italic>\u2009=\u20090.004) and practice (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.490, <jats:italic>p<\/jats:italic>\u2009=\u20090.010). Attitude directly influenced practice (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.193, <jats:italic>p<\/jats:italic>\u2009=\u20090.009).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study revealed inadequate knowledge, moderate attitude, and practice toward cervical precancerous lesions among women in Beijing. Educational interventions should be developed to enhance knowledge in this regard.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2024.1433718","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T10:15:11Z","timestamp":1727864111000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Women\u2019s knowledge, attitude, and practice regarding cervical precancerous lesions: a cross-sectional study in Beijing, China"],"prefix":"10.3389","volume":"12","author":[{"given":"Lingyan","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,10,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"200238","DOI":"10.1016\/j.tvr.2022.200238","article-title":"Cervical cancer therapies: current challenges and future perspectives","volume":"13","author":"Burmeister","year":"2022","journal-title":"Tumour Virus Res"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/s0140-6736(18)32470-x","article-title":"Cervical cancer","volume":"393","author":"Cohen","year":"2019","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1093\/eurpub\/ckae084","article-title":"Analysis of the global burden of cervical cancer in young women aged 15-44 years old","volume":"34","author":"Zhang","year":"2024","journal-title":"Eur J Pub Health"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1001\/jama.2023.13174","article-title":"Cervical Cancer screening: a review","volume":"330","author":"Perkins","year":"2023","journal-title":"JAMA"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"2404","DOI":"10.1002\/cncr.30667","article-title":"Cervical cancer: a global health crisis","volume":"123","author":"Small","year":"2017","journal-title":"Cancer"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1097\/LGT.0000000000000525","article-title":"2019 ASCCP risk-based management consensus guidelines for abnormal cervical Cancer screening tests and Cancer precursors","volume":"24","author":"Perkins","year":"2020","journal-title":"J Low Genit Tract Dis"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.currproblcancer.2018.01.010","article-title":"Management of cervical premalignant lesions","volume":"42","author":"Basu","year":"2018","journal-title":"Curr Probl Cancer"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1804","DOI":"10.1245\/s10434-023-14737-0","article-title":"Laparoscopic-assisted vaginal Trachelectomy with prophylactic Cerclage: a safe fertility-sparing treatment for early stage cervical Cancer","volume":"31","author":"Pavone","year":"2024","journal-title":"Ann Surg Oncol"},{"key":"ref9","volume-title":"NCCN clinical practice guidelines in oncology (NCCN guidelines). 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