{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:27:40Z","timestamp":1791894460136,"version":"4.3.4"},"reference-count":52,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Previous studies on the association of adolescent obesity with comorbid diseases in Israel were conducted predominantly in the Israeli Jewish population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Goal<\/jats:title><jats:p>To compare associations of adolescent obesity with Hypertension (HTN), Diabetes Mellitus type 2 (DM2), and Polycystic ovaries (PCO), singly or in combination, between Arabs and Jews in Israel.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross-sectional study of 313,936 Arab adolescents aged 14\u201319\u202fyears between the years 2007\u20132022, and 289,616 adolescents in a matched Jewish comparison group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The crude prevalence of comorbidities increased consistently from the \u2018underweight\u2019 to the \u2018class 3 obesity\u2019 category (from 0.24 to 6.41%, from 0.32 to 4.59%, and from 0.49 to 5.35% for HTN, DM2 and PCO, respectively). Compared to the reference \u2018normal weight\u2019 category, an incremental increase of aOR was observed by increasing weight category. The aORs for the \u2018class 3 obesity\u2019 category (95% CIs) were 26.00 (21.62\u201331.10), 10.82 (8.83\u201313.14), and 6.06 (95% CI 4.57\u20137.87) for HTN, DM2, and PCO, respectively. In the Jewish comparison group, lower aORs for HTN and DM2 were observed in the \u2018class 3 obesity\u2019 category. The increase in aORs with the increase in weight categories was more striking in cases of multiple comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The finding of a strong association of obesity severity with major cardiometabolic consequences in adolescence, as well as the unique ethnic features of these associations, can help focus national health initiatives on vulnerable adolescent groups.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2024.1443756","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T05:11:32Z","timestamp":1733980292000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Associations of adolescent obesity with hypertension, diabetes mellitus and polycystic ovaries in Arabs and Jews in Israel\u2014a nationwide study"],"prefix":"10.3389","volume":"12","author":[{"given":"Yulia","family":"Treister-Goltzman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Nemet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idan","family":"Menashe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/s12933-020-01052-1","article-title":"Cardiovascular morbidity, diabetes and cancer risk among children and adolescents with severe obesity","volume":"19","author":"Bendor","year":"2020","journal-title":"Cardiovasc Diabetol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1097675","DOI":"10.3389\/fpubh.2023.1097675","article-title":"Cardiometabolic risk factors among children who are affected by overweight, obesity and severe obesity","volume":"11","author":"Nur Zati Iwani","year":"2023","journal-title":"Front Public Health"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"3051","DOI":"10.1210\/clinem\/dgad361","article-title":"Childhood obesity, diabetes. 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