{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T20:53:25Z","timestamp":1784062405572,"version":"3.55.0"},"reference-count":74,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:p>Older adults residing in long-term care often experience declines in physical and cognitive functions despite the access to in-house physical activity (PA) programs. This study aimed to evaluate the associations of PA with physical function and global cognitive function in older adults living in long-term care, while examining potential sex differences. A cross-sectional analysis of baseline data from a two-arm cluster randomized controlled trial was conducted, involving 67 participants (34 men, 33 women). PA levels were assessed using tri-axial accelerometers. Physical function, including muscular strength, postural sway, and Short Physical Performance Battery (SPPB) and cognitive function were measured. Spearman correlation analysis revealed no significant associations between PA metrics and muscular strength, postural sway, or global cognitive function across the entire samples (<jats:italic>p<\/jats:italic> \u2265\u20090.091). Multiple linear regression models were developed for the entire sample, males, and females to examine the associations between PA and physical function measures and global cognitive function. After adjustments for confounders, light PA was significantly associated with higher SPPB sub-scores (gait: <jats:italic>\u03b2<\/jats:italic> =\u20090.600, <jats:italic>p<\/jats:italic> &amp;lt;\u20090.001; sit-to-stand: <jats:italic>\u03b2<\/jats:italic> =\u20090.574, <jats:italic>p<\/jats:italic> &amp;lt;\u20090.001), faster usual gait speed (<jats:italic>\u03b2<\/jats:italic> =\u20090.659, <jats:italic>p<\/jats:italic> =\u20090.012), and shorter sit-to-stand times (<jats:italic>\u03b2<\/jats:italic> =\u2009\u22120.305, <jats:italic>p<\/jats:italic> =\u20090.041) across the whole sample. Similar significant associations were observed in males between light PA and SPPB scores (total: <jats:italic>\u03b2<\/jats:italic> =\u20090.319, <jats:italic>p<\/jats:italic> =\u20090.040; gait: <jats:italic>\u03b2<\/jats:italic> =\u20090.532, <jats:italic>p<\/jats:italic> &amp;lt;\u20090.001; sit-to-stand: <jats:italic>\u03b2<\/jats:italic> =\u20090.417, <jats:italic>p<\/jats:italic> =\u20090.009), usual gait speed (<jats:italic>\u03b2<\/jats:italic> =\u20090.762, <jats:italic>p<\/jats:italic> =\u20090.017), and sit-to-stand times (<jats:italic>\u03b2<\/jats:italic> =\u2009\u22120.677, <jats:italic>p<\/jats:italic> &amp;lt;\u20090.001). In females, a significant association was found between light PA and global cognitive function (<jats:italic>\u03b2<\/jats:italic> =\u20090.319, <jats:italic>p<\/jats:italic> =\u20090.012) after adjusting for confounders. This study highlights sex differences in the association of accelerometer-determined PA with physical and cognitive function in older adults living in long-term care, with LPA showing beneficial effects, especially for physical function in males and for cognitive function in females.<\/jats:p>","DOI":"10.3389\/fpubh.2024.1446286","type":"journal-article","created":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T06:10:43Z","timestamp":1731305443000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Sex differences in the associations of accelerometer-determined physical activity with physical and cognitive function in older adults living in long-term care"],"prefix":"10.3389","volume":"12","author":[{"given":"Ziwei","family":"Zeng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun Liang","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberley Stefanie","family":"van Schooten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"4123","DOI":"10.3969\/j.issn.1005-9202.2022.16.071","article-title":"Development status, causes and countermeasures of population aging in China","volume":"42","author":"Liu","year":"2022","journal-title":"Chine J Gerontol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1093\/ageing\/afu189","article-title":"The challenges of human population ageing","volume":"44","author":"Sander","year":"2015","journal-title":"Age Ageing"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"e0183945","DOI":"10.1371\/journal.pone.0183945","article-title":"Individual and institutional factors associated with functional disability in nursing home residents: an observational study with multilevel analysis","volume":"12","author":"Serrano-Urrea","year":"2017","journal-title":"PLoS One"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.jamda.2008.01.008","article-title":"Nursing homes in China","volume":"9","author":"Chu","year":"2008","journal-title":"J Am Med Dir Assoc"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1093\/gerona\/59.3.m255","article-title":"Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care","volume":"59","author":"Fried","year":"2004","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"719","DOI":"10.2147\/CIA.S59448","article-title":"Falls and cognitive decline in Mexican Americans 75 years and older","volume":"9","author":"Padubidri","year":"2014","journal-title":"Clin Interv Aging"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1109\/TBME.2011.2181844","article-title":"Assessment of cognitive decline through quantitative analysis of the timed up and go test","volume":"59","author":"Greene","year":"2011","journal-title":"IEEE Trans Biomed Eng"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1093\/gerona\/glx003","article-title":"Gait speed and grip strength reflect cognitive impairment and are modestly related to incident cognitive decline in memory clinic patients with subjective cognitive decline and mild cognitive impairment: findings from the 4C study","volume":"72","author":"Hooghiemstra","year":"2017","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1111\/j.1532-5415.2008.01819.x","article-title":"At the tipping point: predicting severe mobility difficulty in vulnerable older women","volume":"56","author":"Rivera","year":"2008","journal-title":"J Am Geriatr Soc"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"M294","DOI":"10.1093\/gerona\/57.5.m294","article-title":"Performance tests and disability: developing an objective index of mobility-related limitation in older populations","volume":"57","author":"Lan","year":"2002","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1056\/NEJMoa0909087","article-title":"Trajectories of disability in the last year of life","volume":"362","author":"Gill","year":"2010","journal-title":"N Engl J Med"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1159\/000505741","article-title":"Global mapping of interventions to improve quality of life of patients with Alzheimer\u2019s disease during 1990-2018","volume":"48","author":"Hoang","year":"2019","journal-title":"Dement Geriatr Cogn Disord"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"958","DOI":"10.1007\/s11606-015-3206-9","article-title":"Cognitive function and health literacy decline in a cohort of aging English adults","volume":"30","author":"Kobayashi","year":"2015","journal-title":"J Gen Intern Med"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1016\/j.cger.2013.07.003","article-title":"Classification and epidemiology of MCI","volume":"29","author":"Roberts","year":"2013","journal-title":"Clin Geriatr Med"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1249\/MSS.0b013e3181a0c95c","article-title":"American College of Sports Medicine position stand. Exercise and physical activity for older adults","volume":"41","author":"Chodzko-Zajko","year":"2009","journal-title":"Med Sci Sports Exerc"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"888851","DOI":"10.3389\/fpsyg.2022.888851","article-title":"Effects of chronic physical exercise or multicomponent exercise programs on the mental health and cognition of older adults living in a nursing home: a systematic review of studies from the past 10 years","volume":"13","author":"Da Silva","year":"2022","journal-title":"Front Psychol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1016\/j.apmr.2022.11.002","article-title":"Efficacy of therapeutic exercise on activities of daily living and cognitive function among older residents in long-term care facilities: a systematic review and meta-analysis of randomized controlled trials","volume":"104","author":"Okamae","year":"2023","journal-title":"Arch Phys Med Rehabil"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"CD004294","DOI":"10.1002\/14651858.CD004294.pub3","article-title":"Physical rehabilitation for older people in long-term care","volume":"2","author":"Crocker","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1177\/0733464815570667","article-title":"\u201cAre you sure?\u201d lapses in self-reported activities among healthy older adults reporting online","volume":"35","author":"Wild","year":"2016","journal-title":"J Appl Gerontol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1249\/MSS.0000000000000517","article-title":"Definition, measurement, and health risks associated with sedentary behavior","volume":"47","author":"Gibbs","year":"2015","journal-title":"Med Sci Sports Exerc"},{"key":"ref21","volume-title":"Global recommendations on physical activity for health","year":"2010"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.maturitas.2014.11.010","article-title":"The association between sedentary behaviour, moderate\u2013vigorous physical activity and frailty in NHANES cohorts","volume":"80","author":"Blodgett","year":"2015","journal-title":"Maturitas"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1007\/s12170-016-0485-6","article-title":"Sedentary behavior and cardiovascular risk in older adults: a scoping review","volume":"10","author":"Hajduk","year":"2016","journal-title":"Curr Cardiovasc Risk Rep"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s11556-011-0081-1","article-title":"Impact of physical activity and sedentary behaviour on fall risks in older people: a systematic review and meta-analysis of observational studies","volume":"9","author":"Thibaud","year":"2012","journal-title":"Eur Rev Aging Phys Act"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.2105\/AJPH.2014.302540","article-title":"Sedentary behavior as a risk factor for physical frailty independent of moderate activity: results from the osteoarthritis initiative","volume":"105","author":"Song","year":"2015","journal-title":"Am J Public Health"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2458-14-333","article-title":"Sedentary behavior and health outcomes among older adults: a systematic review","volume":"14","author":"Rezende","year":"2014","journal-title":"BMC Public Health"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.trci.2017.04.001","article-title":"Sedentary behavior as a risk factor for cognitive decline? A focus on the influence of glycemic control in brain health","volume":"3","author":"Wheeler","year":"2017","journal-title":"Alzheimers Dement (N Y)"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1093\/aje\/kwm390","article-title":"Amount of time spent in sedentary behaviors in the United States, 2003-2004","volume":"167","author":"Matthews","year":"2008","journal-title":"Am J Epidemiol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1093\/eurheartj\/ehq451","article-title":"Sedentary time and cardio-metabolic biomarkers in US adults: NHANES 2003-06","volume":"32","author":"Healy","year":"2011","journal-title":"Eur Heart J"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"9160504","DOI":"10.1155\/2017\/9160504","article-title":"Association between sedentary behaviour and physical, cognitive, and psychosocial status among older adults in assisted living","volume":"2017","author":"Leung","year":"2017","journal-title":"Biomed Res Int"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.archger.2014.08.010","article-title":"Differences in body composition and physical functions associated with sarcopenia in Chinese elderly: reference values and prevalence","volume":"60","author":"Zeng","year":"2015","journal-title":"Arch Gerontol Geriatr"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"213","DOI":"10.3390\/healthcare12020213","article-title":"Functional fitness norms of community-dwelling older adults in southern rural Taiwan: a cross-sectional study","volume":"12","author":"Wang","year":"2024","journal-title":"Healthcare (Basel)"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1111\/jnu.12132","article-title":"Gender differences in the predictors of physical activity among assisted living residents","volume":"47","author":"Chen","year":"2015","journal-title":"J Nurs Scholarsh"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"e082403","DOI":"10.1136\/bmjopen-2023-082403","article-title":"Effects of a multicomponent physical activity programme, mobility-fit, compared with a standard care lower limb strengthening programme, to promote safe mobility among older adults in care facilities: protocol for a cluster randomised controlled trial","volume":"14","author":"Yang","year":"2024","journal-title":"BMJ Open"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3390\/ijerph18073577","article-title":"Normative data of objectively measured physical activity and sedentary time in community-dwelling older Japanese","volume":"18","author":"Yatsugi","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1123\/jpah.2015-0090","article-title":"Associations of sedentary time and breaks in sedentary time with disability in instrumental activities of daily living in community-dwelling older adults","volume":"13","author":"Chen","year":"2016","journal-title":"J Phys Act Health"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2458-14-1307","article-title":"Identifying associations between sedentary time and cardio-metabolic risk factors in working adults using objective and subjective measures: a cross-sectional analysis","volume":"14","author":"Honda","year":"2014","journal-title":"BMC Public Health"},{"key":"ref38","first-page":"507","article-title":"Tri-axial accelerometer-determined daily physical activity and sedentary behavior of suburban community-dwelling older Japanese adults","volume":"14","author":"Chen","year":"2015","journal-title":"J Sports Sci Med"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"S531","DOI":"10.1249\/01.mss.0000185657.86065.98","article-title":"Conducting accelerometer-based activity assessments in field-based research","volume":"37","author":"Trost","year":"2005","journal-title":"Med Sci Sports Exerc"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1123\/jpah.10.5.742","article-title":"How many hours are enough? Accelerometer wear time may provide bias in daily activity estimates","volume":"10","author":"Herrmann","year":"2013","journal-title":"J Phys Act Health"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1479-5868-8-62","article-title":"How many days of monitoring predict physical activity and sedentary behaviour in older adults?","volume":"8","author":"Hart","year":"2011","journal-title":"Int J Behav Nutr Phys Act"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/1479-5868-9-40","article-title":"Measured and perceived environmental characteristics are related to accelerometer defined physical activity in older adults","volume":"9","author":"Strath","year":"2012","journal-title":"Int J Behav Nutr Phys Act"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"S512","DOI":"10.1249\/01.mss.0000185659.11982.3d","article-title":"Calibration of accelerometer output for adults","volume":"37","author":"Matthew","year":"2005","journal-title":"Med Sci Sports Exerc"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1249\/mss.0b013e3180616b27","article-title":"Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association","volume":"39","author":"Haskell","year":"2007","journal-title":"Med Sci Sports Exerc"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.physio.2004.08.005","article-title":"A comparison of two portable dynamometers in the assessment of shoulder and elbow strength","volume":"91","author":"Vermeulen","year":"2005","journal-title":"Physiotherapy"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"e0140822","DOI":"10.1371\/journal.pone.0140822","article-title":"Assessment of lower limb muscle strength and power using hand-held and fixed dynamometry: a reliability and validity study","volume":"10","author":"Mentiplay","year":"2015","journal-title":"PLoS One"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1136\/jech-2013-203611","article-title":"Midlife and late-life handgrip strength and risk of cause-specific death in a general Japanese population: the Hisayama study","volume":"68","author":"Kishimoto","year":"2014","journal-title":"J Epidemiol Community Health"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1093\/ptj\/83.3.237","article-title":"A physiological profile approach to falls risk assessment and prevention","volume":"83","author":"Lord","year":"2003","journal-title":"Phys Ther"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"M221","DOI":"10.1093\/gerona\/55.4.m221","article-title":"Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery","volume":"55","author":"Guralnik","year":"2000","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"M85","DOI":"10.1093\/geronj\/49.2.m85","article-title":"A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission","volume":"49","author":"Guralnik","year":"1994","journal-title":"J Gerontol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"2681","DOI":"10.2147\/NDT.S269243","article-title":"Montreal cognitive assessment\u2014single cutoff achieves screening purpose","volume":"16","author":"Yeung","year":"2020","journal-title":"Neuropsychiatr Dis Treat"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"504","DOI":"10.12809\/hkmj144219","article-title":"A validation study of the Hong Kong version of Montreal cognitive assessment (HK-MoCA) in Chinese older adults in Hong Kong","volume":"20","author":"Yeung","year":"2014","journal-title":"Hong Kong Med J"},{"key":"ref53","volume-title":"Straightforward statistics for the behavioral sciences","author":"Evans","year":"1996"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3390\/ijerph192315655","article-title":"Relationships of physical activity, depression, and sleep with cognitive function in community-dwelling older adults","volume":"19","author":"Kim","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"2725","DOI":"10.1038\/s41598-022-06725-3","article-title":"Relationship between physical activity and cognitive functioning among older Indian adults","volume":"12","author":"Kumar","year":"2022","journal-title":"Sci Rep"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1002\/jcsm.12065","article-title":"Accelerometer-determined physical activity, muscle mass, and leg strength in community-dwelling older adults","volume":"7","author":"Foong","year":"2016","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.amepre.2004.12.008","article-title":"Prospective study of physical activity and physical function in early old age","volume":"28","author":"Hillsdon","year":"2005","journal-title":"Am J Prev Med"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.amepre.2011.06.035","article-title":"Physical activity across adulthood and physical performance in midlife: findings from a British birth cohort","volume":"41","author":"Cooper","year":"2011","journal-title":"Am J Prev Med"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/1477-7525-9-47","article-title":"Longitudinal association of physical activity and sedentary behavior during leisure time with health-related quality of life in community-dwelling older adults","volume":"9","author":"Balboa-Castillo","year":"2011","journal-title":"Health Qual Life Outcomes"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1093\/oxfordjournals.aje.a116747","article-title":"Maintaining mobility in late life. II. Smoking, alcohol consumption, physical activity, and body mass index","volume":"137","author":"LaCroix","year":"1993","journal-title":"Am J Epidemiol"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"e62","DOI":"10.2105\/AJPH.2012.301008","article-title":"Adopting an active lifestyle during adulthood and health-related quality of life: the Doetinchem cohort study","volume":"102","author":"van Oostrom","year":"2012","journal-title":"Am J Public Health"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"E306","DOI":"10.9778\/cmajo.20180097","article-title":"Trends in site of death and health care utilization at the end of life: a population-based cohort study","volume":"7","author":"Hill","year":"2019","journal-title":"CMAJ Open"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1016\/j.jamda.2015.06.004","article-title":"Hospitalization and mortality rates in long-term care facilities: does for-profit status matter?","volume":"16","author":"Tanuseputro","year":"2015","journal-title":"J Am Med Dir Assoc"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"1769","DOI":"10.1007\/s40279-017-0724-0","article-title":"Health benefits of light-intensity physical activity: a systematic review of accelerometer data of the national health and nutrition examination survey (NHANES)","volume":"47","author":"Fuezeki","year":"2017","journal-title":"Sports Med"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1037\/0278-6133.21.5.452","article-title":"Adherence to exercise prescriptions: effects of prescribing moderate versus higher levels of intensity and frequency","volume":"21","author":"Perri","year":"2002","journal-title":"Health Psychol"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"1282482","DOI":"10.3389\/fspor.2023.1282482","article-title":"Moving beyond moderate-to-vigorous physical activity: the role of light physical activity during adolescence","volume":"5","author":"Telford","year":"2023","journal-title":"Front Sports Act Living"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1093\/gerona\/61.10.1059","article-title":"The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study","volume":"61","author":"Goodpaster","year":"2006","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"e034645","DOI":"10.1136\/bmjopen-2019-034645","article-title":"Objectively assessed physical activity patterns and physical function in community-dwelling older adults: a cross-sectional study in Taiwan","volume":"10","author":"Hsueh","year":"2020","journal-title":"BMJ Open"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"2258","DOI":"10.3390\/s21072258","article-title":"Association between self-reported and accelerometer-based estimates of physical activity in Portuguese older adults","volume":"21","author":"Domingos","year":"2021","journal-title":"Sensors"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"2243","DOI":"10.1016\/j.neubiorev.2013.04.005","article-title":"Beneficial effects of physical exercise on neuroplasticity and cognition","volume":"37","author":"H\u00f6tting","year":"2013","journal-title":"Neurosci Biobehav Rev"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1002\/cncr.30987","article-title":"Randomized controlled trial of increasing physical activity on objectively measured and self-reported cognitive functioning among breast cancer survivors: the memory & motion study","volume":"124","author":"Hartman","year":"2018","journal-title":"Cancer"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"3472","DOI":"10.1038\/s41598-020-59458-6","article-title":"Physical fitness and physical activity association with cognitive function and quality of life: baseline cross-sectional analysis of the PREDIMED-plus trial","volume":"10","author":"Daimiel","year":"2020","journal-title":"Sci Rep"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1007\/s00421-010-1424-8","article-title":"Yearlong physical activity and sarcopenia in older adults: the Nakanojo study","volume":"109","author":"Park","year":"2010","journal-title":"Eur J Appl Physiol"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1111\/j.1532-5415.1997.tb03193.x","article-title":"Physical activity and the changes in maximal isometric strength in men and women from the age of 75 to 80 years","volume":"45","author":"Rantanen","year":"1997","journal-title":"J Am Geriatr Soc"}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2024.1446286\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T06:10:48Z","timestamp":1731305448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2024.1446286\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,11]]},"references-count":74,"alternative-id":["10.3389\/fpubh.2024.1446286"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2024.1446286","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,11]]},"article-number":"1446286"}}