{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T01:42:31Z","timestamp":1793497351849,"version":"4.5.0"},"reference-count":23,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"Background<\/jats:title>Placental abruption is a critical obstetric condition characterized by the premature separation of the placenta from the uterus, leading to severe maternal and fetal complications. In Ethiopia, the maternal and perinatal morbidity and mortality rates are alarmingly high, and placental abruption significantly contributes to these adverse outcomes. Despite its severity, there is a lack of comprehensive data on the burden, risk factors, and outcomes associated with placental abruption in the Ethiopian context. Thus, the study aimed to investigate the adverse perinatal outcomes of placental abruption and the factors associated with these outcomes among pregnant women admitted to the University of Gondar Comprehensive Specialized Hospital in Ethiopia.<\/jats:p><\/jats:sec>Method<\/jats:title>An institution-based retrospective cross-sectional study was conducted among 367 pregnant women who were admitted and managed for placental abruption from January 1, 2021, to January 1, 2023, at the University of Gondar Comprehensive Specialized Hospital. A simple random sample method was employed to choose the medical records. Data was collected using a checklist prepared with the KOBO collect tool and then exported to SPSS version 25.0. Variables having a p<\/jats:italic>-value of less than 0.05 were deemed significant in the multivariable logistic regression analysis that was done. The adjusted odds ratio with a 95% confidence interval was reported.<\/jats:p><\/jats:sec>Result<\/jats:title>The prevalence of adverse perinatal outcome of placental abruption was 39.2, 95% CI: 34.3\u201344.1. The most common adverse outcomes were prematurity (25.6%), low birth weight (25.6%), and NICU admission (13.9%). Severe placental abruption [AOR (CI)\u202f=\u202f8.82 (4.48\u201317.31)] and abruption at preterm gestation [AOR (CI)\u202f=\u202f18.71 (9.59\u201336.42)] were significant predictors of adverse perinatal outcomes.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The adverse perinatal outcomes of pregnancies complicated by placental abruption in this study were higher compared to other studies in Ethiopia. The degree of placental abruption and gestational age at diagnosis were significant associates of adverse perinatal outcomes. The study highlights the critical need for patient-centered counseling on antenatal bleeding to encourage early healthcare-seeking behavior, close follow up for those undergoing expectant management and the early detection and management of placental abruption to improve perinatal outcomes.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2024.1453117","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T05:29:14Z","timestamp":1736227754000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Perinatal outcomes and predictors of placental abruption: a retrospective study in an Ethiopian tertiary care center"],"prefix":"10.3389","volume":"12","author":[{"given":"Mesfin","family":"Tadese","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gebresenbet","family":"Getachew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tirusew Nigussie","family":"Kebede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toyba Ebrahim","family":"Yesuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saba Desta","family":"Tessema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wogene Asefa","family":"Damesa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gebeyehu Shumet","family":"Solomon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"S1313","DOI":"10.1016\/j.ajog.2022.06.059","article-title":"Placental abruption at near-term and term gestations: pathophysiology, epidemiology, diagnosis, and management","volume":"228","author":"Brandt","year":"2023","journal-title":"Am J Obstet Gynecol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1111\/aogs.12030","article-title":"Decreasing perinatal mortality in placental abruption","volume":"92","author":"Tikkanen","year":"2013","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"2321485","DOI":"10.1080\/14767058.2024.2321485","article-title":"Potential prevention of stillbirth caused by placental abruption: a regional population-based study in 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