{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:30:37Z","timestamp":1753893037417,"version":"3.41.2"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:p>Sendero Health Plans, an Affordable Care Act (ACA) health insurance company, conducted a cross-sectional survey in December 2020 to assess individual perceptions of the COVID-19 vaccine development and approval processes and their plan to obtain the COVID-19 vaccine in Central Texas at the time of initial availability. A logistic regression model was developed to identify factors associated with individual plans to obtain a vaccine when it became available. A total of 500 (77.25%) of the 645 respondents in this analysis planned to obtain a COVID-19 vaccine when it became available. The logistic regression model was statistically significant [\u03c7<jats:sup>2<\/jats:sup>(19)\u202f=\u202f314.41, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.001]. Plans to obtain a COVID-19 vaccine were significantly associated with perceptions of vaccine safety (POR: 23.45, <jats:italic>p<\/jats:italic>\u202f=\u202f0.001, 95% CI: 3.10, 58.34), vaccine protectiveness (POR: 15.55, <jats:italic>p<\/jats:italic>\u202f&amp;lt;\u202f0.001, 95% CI: 3.55, 68.06), and transparency of the authorization process (POR: 1.33, <jats:italic>p<\/jats:italic>\u202f=\u202f0.024, 95% CI: 1.15, 7.15). Perceptions regarding the safety, protectiveness, and authorization process of the COVID-19 vaccines are associated with individual plans to obtain the vaccines. This study provides insights into factors that influence vaccination intent and key barriers affecting vaccine hesitancy during a public health crisis.<\/jats:p>","DOI":"10.3389\/fpubh.2025.1446984","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T05:22:07Z","timestamp":1750742527000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Perceptions of the safety, development, and approval process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines among individuals with Affordable Care Act health insurance in Central Texas at the time of initial vaccine availability"],"prefix":"10.3389","volume":"13","author":[{"given":"Carlos","family":"Lopez Bray","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomi","family":"Tamez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wesley","family":"Durkalski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R.","family":"Litaker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"year":"2019","key":"ref1"},{"year":"2020","key":"ref2"},{"year":"2020","key":"ref3"},{"volume-title":"U.S. Food and Drug Administration (FDA). Authorization of Emergency Use of Two Biological Products During COVID-19 Pandemic, 86 FR 5200","year":"2021","key":"ref4"},{"volume-title":"Representative Greg Walden. An act to amend the Federal Food, Drug, and cosmetic act to authorize additional emergency uses for medical products to reduce deaths and severity of injuries caused by agents of war, and for other purposes, HR 4374, 115th congress","year":"2017","key":"ref5"},{"year":"2017","key":"ref6"},{"year":"2020","key":"ref7"},{"year":"2020","key":"ref8"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1177\/0890117121998141","article-title":"Extent of and reasons for vaccine hesitancy in adults at high-risk for pneumococcal disease","volume":"35","author":"Gatwood","year":"2021","journal-title":"Am J Health Promot"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1763","DOI":"10.4161\/hv.24657","article-title":"Vaccine hesitancy: an overview","volume":"9","author":"Dub\u00e9","year":"2013","journal-title":"Hum Vaccin Immunother"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1089\/hs.2021.0079","article-title":"Assessing determinants of COVID-19 vaccine hesitancy in Nevada","volume":"19","author":"Coughenour","year":"2021","journal-title":"Health Secur"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"368","DOI":"10.3390\/ijerph19010368","article-title":"Sociodemographic factors associated with vaccine hesitancy in Central Texas immediately prior to COVID-19 vaccine availability","volume":"19","author":"Litaker","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/21645515.2021.1950504","article-title":"COVID-19 vaccine hesitancy: misinformation and perceptions of vaccine safety","volume":"18","author":"Kricorian","year":"2021","journal-title":"Hum Vaccin Immunother"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"582","DOI":"10.3390\/vaccines8040582","article-title":"Influences on attitudes regarding potential COVID-19 vaccination in the United States","volume":"8","author":"Pogue","year":"2020","journal-title":"Vaccine"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.3390\/vaccines10101739","article-title":"COVID-19 vaccine acceptors, refusers, and the moveable middle: a qualitative study from Central Texas","volume":"10","author":"Litaker","year":"2022","journal-title":"Vaccine"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1093\/aje\/kwac029","article-title":"Factors associated with willingness to receive a COVID-19 vaccine among 23, 819 adults aged 50 years or older: an analysis of the Canadian longitudinal study on aging","volume":"191","author":"Basta","year":"2022","journal-title":"Am J Epidemiol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"215013272110407","DOI":"10.1177\/21501327211040746","article-title":"Sociodemographic determinants of COVID-19 vaccine hesitancy, fear of infection, and protection self-efficacy","volume":"12","author":"McElfish","year":"2021","journal-title":"J Prim Care Community Health"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"352","DOI":"10.3390\/vaccines10030352","article-title":"COVID-19 vaccine hesitancy: the role of socioeconomic factors and spatial effects","volume":"10","author":"Lee","year":"2022","journal-title":"Vaccine"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.vaccine.2021.11.040","article-title":"Disparities in national and state estimates of COVID-19 vaccination receipt and intent to vaccinate by race\/ethnicity, income, and age group among adults \u2265 18 years, United States","volume":"40","author":"Nguyen","year":"2021","journal-title":"Vaccine"},{"year":"2021","author":"Sullender","key":"ref20"},{"year":"2024","key":"ref21"},{"year":"2020","key":"ref22"}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2025.1446984\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T05:22:09Z","timestamp":1750742529000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2025.1446984\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,24]]},"references-count":22,"alternative-id":["10.3389\/fpubh.2025.1446984"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2025.1446984","relation":{},"ISSN":["2296-2565"],"issn-type":[{"type":"electronic","value":"2296-2565"}],"subject":[],"published":{"date-parts":[[2025,6,24]]},"article-number":"1446984"}}