{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T10:59:09Z","timestamp":1793098749683,"version":"4.5.0"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Evidence of the association between change in depressive symptom scores and new-onset dual sensory impairment (DSI) remain underexplored. We aimed to investigate the relationship between depressive symptom scores and the risk of new-onset DSI in middle-aged and older adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included 3,237 participants. The Center for Epidemiologic Studies Depression Scale (CES-D-10) was used to assess depression symptoms. CES-D-10 scores were classified according to the K-means cluster analysis. Subsequently, the logistic regression analysis was used to determine the association between the change in CES-D-10 scores and DSI. Additionally, restricted cubic splines (RCS) were employed to examine whether there was a linear correlation between cumulative CES-D-10 scores and DSI. We also explored whether the association of CES-D-10 scores with DSI varies across different subgroups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One thousand and sixty one out of 3,237 participants had a new-onset DSI during 3 years. Compared to class 1 with the best control of depressive state, the OR for class 2 with good control was 1.54 (95% CI, 1.28, 1.85), the OR for class 3 with moderate control was 1.59 (95% CI, 1.22, 2.07), the OR for class 4 with worse control was 1.62 (95% CI, 1.31, 2.02), and the OR for class 5 with consistently high levels was 1.86 (95% CI, 1.34, 2.57).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Individuals exhibiting suboptimal management of depressive symptoms were more susceptible to developing new-onset DSI, underscoring the need for early depression screening and assessment in the preventative strategies for new-onset DSI.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2025.1520552","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T05:58:38Z","timestamp":1742968718000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Change in depressive 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