{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T14:30:46Z","timestamp":1792420246937,"version":"4.5.0"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T00:00:00Z","timestamp":1740355200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>AIDS is a severe medical condition caused by the human immunodeficiency virus (HIV) that primarily attacks the immune system, specifically CD4+ T lymphocytes (a type of white blood cell crucial for immune response), monocyte macrophages, and dendritic cells. This disease has significant health and socio-economic implications and is one of the primary causes of illness and death globally (UNAIDS, 2022). It presents significant challenges for public health and population well-being, both in developed and developing countries. By conducting a time series analysis, this research seeks to identify any significant changes in HIV rates over the next 4\u202fyears in the Kumba District Hospital and provide valuable insights to inform evidence-based decision-making and strategies for preventing and controlling HIV within the Kumba Health District.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A hospital-based retrospective study on HIV\/AIDS recorded cases was conducted at the Kumba District Hospital. Using data extraction form, hospital records from 2012 to 2022 were reviewed and data extracted and used to make predictions on the number of future incidence cases. Time series analysis using Auto-Regressive Integrated Moving Average (ARIMA) model was done using Statistical Package for the Social Sciences (SPSS) Version 26.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>According to the ARIMA parameter (p,d,q), the results for the Partial Autocorrelation Factor (p) was 1, differencing (d) was 0 and Autocorrelation Factor (q) was 0. Putting these values together, we had the ARIMA model (1,0,0) which predicted an overall increase in HIV incidence cases at the Kumba District Hospital for the upcoming Years (2023\u20132026).<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>The ARIMA model was found to be independent of errors and a perfect fit, with a high R-squared value of 0.764 and a <jats:italic>p<\/jats:italic>-value of 0.410, indicating that the model\u2019s predictions aligned well with the observed data. The model predicted an increase in the number of HIV incidence cases over the coming years (2023\u20132026), potentially suggesting a worsening situation. However, it is important to interpret these predictions with caution and consider other factors that may influence the incidence of HIV in reality.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpubh.2025.1526454","type":"journal-article","created":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T06:36:34Z","timestamp":1740378994000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Significance of the ARIMA epidemiological modeling to predict the rate of HIV and AIDS in the Kumba Health District of Cameroon"],"prefix":"10.3389","volume":"13","author":[{"given":"Arrey Emmanuel","family":"Besong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odette Dzemo","family":"Kibu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvis 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Shey","family":"Nsagha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,2,24]]},"reference":[{"key":"ref1","year":"2024"},{"key":"ref2","year":"2024"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1097\/COH.0000000000000008","article-title":"The 2013 WHO guidelines for antiretroviral therapy: evidence-based recommendations to face new epidemic realities","volume":"8","author":"Doherty","year":"2013","journal-title":"Curr Opin HIV AIDS"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e0269252","DOI":"10.1371\/journal.pone.0269252","article-title":"Adherence barriers and interventions to improve ART adherence in sub-Saharan African countries: a systematic review protocol","volume":"17","author":"Buh","year":"2022","journal-title":"PLoS 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