{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:11:02Z","timestamp":1793412662293,"version":"4.5.0"},"reference-count":64,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Smoking poses a significant threat to global human health, making smoking cessation a controllable means of preventing mortality. Exercise, as a means of promoting a healthy lifestyle, offers substantial benefits to individuals attempting to quit smoking. However, due to variations in experimental populations and conditions, the specific effects and benefits of exercise on smoking cessation remain unclear. In this meta-analysis, we comprehensively evaluated the withdrawal effects of different intensities of exercise on tobacco-dependent individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Statistical analysis and graphing were performed using Stata 14 and Review Manager 5.4 software. A total of 47 literatures, encompassing 57 randomized controlled trials and involving 4,267 tobacco-dependent individuals, were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The meta-analysis results showed that long-term exercise had no significant difference or impact on the degree of tobacco dependence between the exercise and control groups. However, acute exercise was associated with increased tobacco craving (desire and intensity) and more pronounced withdrawal symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Acute aerobic exercise can significantly reduce craving and withdrawal symptoms among individuals attempting to quit smoking, demonstrating a certain role in smoking cessation. Acute aerobic exercise emerges as the most effective form of physical exercise for intervening in tobacco dependence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Systematic review registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link>https:\/\/www.crd.york.ac.uk\/PROSPERO\/<\/jats:ext-link>\n                      , CRD42024550014.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2025.1538833","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T06:11:31Z","timestamp":1739859091000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Effects of exercise intervention on tobacco dependence: a meta-analysis"],"prefix":"10.3389","volume":"13","author":[{"given":"Jinzhi","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zichao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhusheng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"ref1","first-page":"1","volume-title":"World health statistics 2023: monitoring health for the SDGs, sustainable development goals","year":"2023"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.biopha.2016.11.118","article-title":"Cigarette smoke and related risk factors in neurological disorders: an update","volume":"85","author":"G","year":"2017","journal-title":"Biomed Pharmacother"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"100","DOI":"10.3969\/j.issn.1672-5131.2024.05.032","article-title":"Study on the risk of coronary artery stenosis and smoking in patients with COVID-19 pneumonia infection","volume":"22","author":"Zhu","year":"2024","journal-title":"Chinese J CT MRI"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1093\/ntr\/nty029","article-title":"The role of cognitive control in the self-regulation and reinforcement of smoking behavior","volume":"21","author":"Evans","year":"2019","journal-title":"Nicotine Tob Res"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S0005-7894(87)80002-3","article-title":"Long-term effects of behavioral smoking cessation interventions","volume":"18","author":"Glasgow","year":"1987","journal-title":"Behav Ther"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1001\/archpsyc.59.10.930","article-title":"Psychological intervention and antidepressant treatment in smoking cessation","volume":"59","author":"Hall","year":"2002","journal-title":"Arch Gen Psychiatry"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2001.124","article-title":"Overeating: the health risks","volume":"9","author":"Prentice","year":"2001","journal-title":"Obes Res"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"69","DOI":"10.2217\/WHE.12.63","article-title":"Exercise-based smoking cessation interventions among women","volume":"9","author":"Linke","year":"2013","journal-title":"Women\u2019s Health (Lond Engl)"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1186\/s13104-017-2762-y","article-title":"Effect of exercise type on smoking cessation: a meta-analysis of randomized controlled trials","volume":"10","author":"Klinsophon","year":"2017","journal-title":"BMC Res Notes"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1149043","DOI":"10.1080\/2331205X.2016.1149043","article-title":"An initial investigation of smokers\u2019 urges to smoke and their exercise intensity preference: a mixed-methods approach","volume":"3","author":"Zourbanos","year":"2016","journal-title":"Cogent Med"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/j.amjmed.2008.01.015","article-title":"Neurobiology of nicotine addiction: implications for smoking cessation treatment","volume":"121","author":"Benowitz","year":"2008","journal-title":"Am J Med"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"S20","DOI":"10.2337\/dc15-S007","article-title":"4. 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