{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T06:39:35Z","timestamp":1791614375228,"version":"4.3.4"},"reference-count":67,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Public Health"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To construct a prediction model for the risk of depression in the obese population, aiming to facilitate the early identification of high-risk individuals and guide personalized preventive interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This study was based on the data from the China Health and Retirement Longitudinal Study (CHARLS 2015), the Center for Epidemiologic Studies Depression Scale-10 (CES-D10) to assess the depression of obese patients, Lasso regression and multivariable logistic regression were used to select predictors, the construction of a nomogram model, and the use of the random splitting method divided into a training set (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f974) and a validation set (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f418) by the 7:3 method, and the model was evaluated by the ROC curves and the AUC, the H-L goodness-of-fit test, the calibration graphs, and the clinical decision-making curve to assess the model.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 1,392 obese patients were finally included, with a prevalence of depression of 32.68%. Age, respiratory function, renal disease, digestive disease, grip strength, rheumatism and arthritis, and sleep duration were selected to construct the predictive nomogram model of depression risk in obese patients, and the AUCs of the training set and validation set were 0.715 (95% CI\u202f=\u202f0.681\u20130.749) and 0.716 (95% CI\u202f=\u202f0.665\u20130.767). This suggests that the model has moderate discriminatory power. Respectively, the H-L test was statistically insignificant (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;gt;\u202f0.05, H-L test;\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;gt;\u202f0.05). Goodness of fit, calibration curves showed significant agreement between the model and actual observations, and clinical decision curves indicated good model calibration and net benefit.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The model constructed in this study has good efficacy in predicting the occurrence of depression in the obese population and can be used for the early identification of high-risk groups and the adoption of targeted preventive measures to reduce the risk of depression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fpubh.2025.1574386","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:11:35Z","timestamp":1747181495000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Development and validation of a predictive model for depression risk in Chinese obese adults"],"prefix":"10.3389","volume":"13","author":[{"given":"Cong","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiamin","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenguang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ensi","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"406","DOI":"10.16506\/j.1009-6639.2024.04.004","article-title":"Epidemiological status and prevention of overweight and obesity in China","volume":"25","author":"Ll","year":"2024","journal-title":"Chinese J Prevent Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"619","DOI":"10.3760\/cma.j.cn112338-20220402-00253","article-title":"Expert consensus on obesity prevention and treatment in Chinese residents","volume":"43","year":"2022","journal-title":"J Xi\u2019an Jiaotong University (Med Sci)"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1016\/S2213-8587(21)00118-2","article-title":"Health policy and public health implications of obesity in China","volume":"9","author":"Wang","year":"2021","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.semcancer.2023.04.008","article-title":"Obesity-induced thymic involution and cancer risk","volume":"93","author":"Lagou","year":"2023","journal-title":"Semin Cancer Biol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1002\/1878-0261.12772","article-title":"Physical activity, obesity and sedentary behavior in cancer etiology: epidemiologic evidence and biologic mechanisms","volume":"15","author":"Friedenreich","year":"2021","journal-title":"Mol Oncol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1161\/Circresaha.120.316101","article-title":"Obesity phenotypes, diabetes, and cardiovascular diseases","volume":"126","author":"Pich\u00e9","year":"2020","journal-title":"Circ Res"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"3388","DOI":"10.1093\/eurheartj\/ehab454","article-title":"Association between adiposity and cardiovascular outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies","volume":"42","author":"Kim","year":"2021","journal-title":"Eur Heart J"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1038\/s41380-018-0017-5","article-title":"Depression and obesity: evidence of shared biological mechanisms","volume":"24","author":"Milaneschi","year":"2019","journal-title":"Mol Psychiatry"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1038\/ijo.2008.268","article-title":"Depression and anxiety among us adults: associations with body mass index","volume":"33","author":"Zhao","year":"2005","journal-title":"Int J Obes"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.neuropharm.2014.12.034","article-title":"Microglia in neuronal plasticity: influence of stress","volume":"96","author":"Delpech","year":"2015","journal-title":"Neuropharmacology"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"R193","DOI":"10.1186\/cc12887","article-title":"Critical illness induces nutrient-independent adipogenesis and accumulation of alternatively activated tissue macrophages","volume":"17","author":"Marques","year":"2013","journal-title":"Crit Care"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"6613385","DOI":"10.1155\/2021\/6613385","article-title":"Structural brain changes associated with overweight and obesity","volume":"2021","author":"G\u00f3mez-Apo","year":"2021","journal-title":"J Obes"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1172\/Jci76308","article-title":"Emerging roles of gut microbiota and the immune system in the development of the enteric nervous system","volume":"125","author":"Kabouridis","year":"2015","journal-title":"J Clin Invest"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"2837","DOI":"10.2147\/Ndt.S177973","article-title":"Neuroprogression: the hidden mechanism of depression","volume":"14","author":"Ruiz","year":"2018","journal-title":"Neuropsychiatr Dis Treat"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/j.jagp.2023.06.001","article-title":"Neuroinflammation: a modifiable pathway linking obesity, Alzheimer\u2019s disease, and depression","volume":"31","author":"Ly","year":"2023","journal-title":"American J Geriatric Psychiatry: Official J American Association for Geriatric Psychiatry"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"96","DOI":"10.3758\/cabn.1.1.96","article-title":"Enhancement of serotonin uptake by cortisol: a possible link between stress and depression","volume":"1","author":"Tafet","year":"2001","journal-title":"Cogn Affect Behav Neurosci"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1186\/s12916-024-03681-9","article-title":"Dissecting shared genetic architecture between depression and body mass index","volume":"22","author":"Zhang","year":"2024","journal-title":"BMC Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/s11920-022-01326-3","article-title":"Moderators of cognitive behavioral treatment for insomnia on depression and anxiety outcomes","volume":"24","author":"Mirchandaney","year":"2022","journal-title":"Curr Psychiatry Rep"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1186\/s12888-024-06278-x","article-title":"Development and validation of a risk prediction model for cognitive impairment in breast cancer patients","volume":"24","author":"Zhang","year":"2024","journal-title":"BMC Psychiatry"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1038\/s41598-024-83568-0","article-title":"A risk prediction model for endometrial hyperplasia\/endometrial carcinoma in premenopausal women","volume":"15","author":"Li","year":"2025","journal-title":"Sci Rep"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1186\/s12889-018-5834-6","article-title":"Obesity and the onset of depressive symptoms among middle-aged and older adults in China: evidence from the Charls","volume":"18","author":"Luo","year":"2018","journal-title":"BMC Public Health"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1001\/jamapsychiatry.2014.1332","article-title":"Association of serum interleukin 6 and C-reactive protein in childhood with depression and psychosis in young adult life: a population-based longitudinal study","volume":"71","author":"Khandaker","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"3031","DOI":"10.1111\/dom.15630","article-title":"Depression and type 2 diabetes: a causal relationship and mechanistic pathway","volume":"26","author":"Khawagi","year":"2024","journal-title":"Diabetes Obes Metab"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1186\/s12889-023-16288-1","article-title":"Association between depression and blood pressure in community-dwelling older adults: focus on Bushehr elderly health (Beh) program","volume":"23","author":"Farhadi","year":"2023","journal-title":"BMC Public Health"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"101155","DOI":"10.1016\/j.esmoop.2023.101155","article-title":"Anxiety and depression in adult cancer patients: Esmo clinical practice guideline","volume":"8","author":"Grassi","year":"2023","journal-title":"Esmo open"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1016\/j.amjmed.2023.04.036","article-title":"Association of Depression and Cardiovascular Disease","volume":"136","author":"Krittanawong","year":"2023","journal-title":"Am J Med"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"2134","DOI":"10.1016\/j.mayocp.2020.02.035","article-title":"Grip strength and depression symptoms among middle-age and older adults","volume":"95","author":"Marques","year":"2020","journal-title":"Mayo Clin Proc"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1017689","DOI":"10.3389\/fpubh.2023.1017689","article-title":"Physical function, Adl, and depressive symptoms in Chinese elderly: evidence from the Charls","volume":"11","author":"Yan","year":"2023","journal-title":"Front Public Health"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1001\/jamapediatrics.2024.3039","article-title":"Anxiety and depression in youth with chronic pain: a systematic review and Meta-analysis","volume":"178","author":"Dudeney","year":"2024","journal-title":"JAMA Pediatr"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1001\/jama.279.21.1720","article-title":"Depressive symptoms and physical decline in community-dwelling older persons","volume":"279","author":"Penninx","year":"1998","journal-title":"JAMA"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.bbi.2022.04.024","article-title":"Association of depression and obesity with C-reactive protein in Germany: a large nationally representative study","volume":"103","author":"Chae","year":"2022","journal-title":"Brain Behav Immun"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1223015","DOI":"10.3389\/fnagi.2023.1223015","article-title":"Serum uric acid and prognosis in acute ischemic stroke: a dose-response meta-analysis of cohort studies","volume":"15","author":"Zhang","year":"2023","journal-title":"Front Aging Neurosci"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1038\/ki.2013.77","article-title":"Prevalence of depression in chronic kidney disease: systematic review and meta-analysis of observational studies","volume":"84","author":"Palmer","year":"2013","journal-title":"Kidney Int"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"112615","DOI":"10.1016\/j.jep.2020.112615","article-title":"Anti-depressive effects of Kai-Xin-san on lipid metabolism in depressed patients and Cums rats using metabolomic analysis","volume":"252","author":"Zhou","year":"2020","journal-title":"J Ethnopharmacol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1186\/s12888-024-05885-y","article-title":"Association between depressive symptoms and sarcopenia among middle-aged and elderly individuals in China: the mediation effect of activities of daily living (Adl) disability","volume":"24","author":"Li","year":"2024","journal-title":"BMC Psychiatry"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1016\/j.cjca.2020.11.010","article-title":"Missing data in clinical research: a tutorial on multiple imputation","volume":"37","author":"Austin","year":"2021","journal-title":"Can J Cardiol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1016\/S2215-0366(21)00251-0","article-title":"Prevalence of depressive disorders and treatment in China: a cross-sectional epidemiological study","volume":"8","author":"Lu","year":"2021","journal-title":"Lancet Psychiatry"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.bbi.2023.02.009","article-title":"Lung function and risk of incident dementia: a prospective cohort study of 431,834 individuals","volume":"109","author":"Ma","year":"2023","journal-title":"Brain Behav Immun"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/j.jad.2022.04.141","article-title":"Relationships of persistent depressive symptoms with subsequent lung function trajectory and respiratory disease mortality","volume":"309","author":"Han","year":"2022","journal-title":"J Affect Disord"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1016\/j.jad.2019.07.088","article-title":"The association between cardiorespiratory fitness and the incidence of common mental health disorders: a systematic review and meta-analysis","volume":"257","author":"Kandola","year":"2019","journal-title":"J Affect Disord"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"585597","DOI":"10.3389\/fpsyg.2021.585597","article-title":"Chronic lung diseases and the risk of depressive symptoms based on the China health and retirement longitudinal study: a prospective cohort study","volume":"12","author":"Ren","year":"2021","journal-title":"Front Psychol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1097\/Psy.0b013e3181c2ca39","article-title":"Low respiratory function increases the risk of depressive symptoms in later life in men","volume":"72","author":"Giltay","year":"2010","journal-title":"Psychosom Med"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1080\/13685538.2019.1567703","article-title":"Investigation of the effect of kinesiotaping on the respiratory function and depression in male patients with chronic obstructive pulmonary disease: a prospective, randomized, controlled, and single-blind study","volume":"23","author":"Metin \u00d6kmen","year":"2020","journal-title":"Aging Male: Official J Int Society Study Aging Male"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1136\/thx.2006.076430","article-title":"Integrated breathing and relaxation training (the Papworth method) for adults with asthma in primary care: a randomised controlled trial","volume":"62","author":"Holloway","year":"2007","journal-title":"Thorax"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.3390\/healthcare11081071","article-title":"Effectiveness of respiratory rehabilitation in Covid-19\u2019s post-acute phase: a systematic review","volume":"11","author":"Tamburlani","year":"2023","journal-title":"Healthcare (Basel)"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1007\/s12603-018-1041-5","article-title":"Depression and handgrip strength among U.S. adults aged 60 years and older from Nhanes 2011-2014","volume":"22","author":"Brooks","year":"2018","journal-title":"J Nutr Health Aging"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"109537","DOI":"10.1016\/j.jnutbio.2023.109537","article-title":"Solanum melongena extract supplementation protected skeletal muscle and brain damage by regulation of Bdnf\/Pgc1\u03b1\/irisin pathway via brain function-related myokines in high-fat diet induced obese mice","volume":"124","author":"Lee","year":"2024","journal-title":"J Nutr Biochem"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1016\/j.neubiorev.2016.09.026","article-title":"Does intensity or youth affect the neurobiological effect of exercise on major depressive disorder?","volume":"84","author":"Budde","year":"2018","journal-title":"Neurosci Biobehav Rev"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"8323","DOI":"10.1007\/s12035-019-01670-1","article-title":"Physical exercise and Neuroinflammation in major depressive disorder","volume":"56","author":"Ign\u00e1cio","year":"2019","journal-title":"Mol Neurobiol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.1002\/jcsm.12963","article-title":"Muscle strength and incidence of depression and anxiety: findings from the Uk biobank prospective cohort study","volume":"13","author":"Cabanas-S\u00e1nchez","year":"2022","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.jad.2020.01.154","article-title":"Obesity increases the risk of depression in children and adolescents: results from a systematic review and meta-analysis","volume":"267","author":"Rao","year":"2020","journal-title":"J Affect Disord"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1111\/obr.12535","article-title":"Exploring the association between childhood and adolescent obesity and depression: a meta-analysis","volume":"18","author":"Quek","year":"2017","journal-title":"Obes Rev"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"45637","DOI":"10.1038\/srep45637","article-title":"Obesity and depressive symptoms among Chinese people aged 45 and over","volume":"7","author":"Qian","year":"2017","journal-title":"Sci Rep"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"1249208","DOI":"10.3389\/fpubh.2023.1249208","article-title":"Association between activities of daily living and depressive symptoms among older adults in China: evidence from the Charls","volume":"11","author":"Liu","year":"2023","journal-title":"Front Public Health"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.puhe.2021.06.023","article-title":"The relationship between depressive symptoms and activity of daily living disability among the elderly: results from the China health and retirement longitudinal study (Charls)","volume":"198","author":"Feng","year":"2021","journal-title":"Public Health"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1080\/00981389.2017.1397588","article-title":"Depression among older Japanese Americans: the impact of functional (Adl & Iadl) and cognitive status","volume":"57","author":"Kim","year":"2018","journal-title":"Soc Work Health Care"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.jad.2024.06.036","article-title":"Development and validation of a nomogram to predict the depressive symptoms among older adults: a national survey in China","volume":"361","author":"Rong","year":"2024","journal-title":"J Affect Disord"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.jad.2020.12.160","article-title":"Use of machine learning approach to predict depression in the elderly in China: a longitudinal study","volume":"282","author":"Su","year":"2021","journal-title":"J Affect Disord"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"764806","DOI":"10.3389\/fpsyt.2021.764806","article-title":"Comparison of regression and machine learning methods in depression forecasting among home-based elderly Chinese: a community based study","volume":"12","author":"Lin","year":"2021","journal-title":"Front Psychol"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1002\/art.24615","article-title":"Factors associated with depression and suicidal ideation among individuals with arthritis or rheumatism: findings from a representative community survey","volume":"61","author":"Fuller-Thomson","year":"2009","journal-title":"Arthritis Rheum"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"326","DOI":"10.3390\/toxins16070326","article-title":"Urea level and depression in patients with chronic kidney disease","volume":"16","author":"Levassort","year":"2024","journal-title":"Toxins (Basel)"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"2455","DOI":"10.1007\/s40620-024-01998-5","article-title":"Global prevalence of depression in chronic kidney disease: a systematic review and meta-analysis","volume":"37","author":"Adejumo","year":"2024","journal-title":"J Nephrol"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.jad.2022.05.104","article-title":"Bidirectional relations between depression symptoms and chronic kidney disease","volume":"311","author":"Liu","year":"2022","journal-title":"J Affect Disord"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"219","DOI":"10.13479\/j.cnki.jip.2024.01.063","article-title":"Anxiety and depression in patients with different stages of chronic kidney disease","volume":"51","author":"Liu","year":"2024","journal-title":"Int J Psychiatry"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.jad.2024.08.200","article-title":"Associations between sleep duration, depression status, and cognitive function among Chinese elderly: a community-based study","volume":"366","author":"Ding","year":"2024","journal-title":"J Affect Disord"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1002\/da.22386","article-title":"Sleep duration and depression among adults: a Meta-analysis of prospective studies","volume":"32","author":"Zhai","year":"2015","journal-title":"Depress Anxiety"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.copsyc.2019.12.002","article-title":"Depression and sleep: what has the treatment research revealed and could the Hpa axis be a potential mechanism?","volume":"34","author":"Asarnow","year":"2020","journal-title":"Curr Opin Psychol"}],"updated-by":[{"DOI":"10.3389\/fpubh.2025.1735400","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000}}],"container-title":["Frontiers in Public Health"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2025.1574386\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T18:01:59Z","timestamp":1763402519000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpubh.2025.1574386\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,14]]},"references-count":67,"alternative-id":["10.3389\/fpubh.2025.1574386"],"URL":"https:\/\/doi.org\/10.3389\/fpubh.2025.1574386","relation":{},"ISSN":["2296-2565"],"issn-type":[{"value":"2296-2565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,14]]},"article-number":"1574386"}}